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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 28-AUG-2013

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_12092 [new locus tag: HMPREF0837_RS10030 ]
  • pan locus tag?: PNEUPAN003390000
  • symbol: HMPREF0837_12092
  • pan gene symbol?: galE_3
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_12092 [new locus tag: HMPREF0837_RS10030 ]
  • symbol: HMPREF0837_12092
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1917170..1917364
  • length: 195
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP001993 (1917170..1917364) NCBI
  • BioCyc: see HMPREF0837_RS10030
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGAACTACCTATTTCAAGAAGACAGTTCTTCTCAAATCTTTAACTTAGGAACTAAAAAA
    GGCTATACTATCAAAGAAATCTTTAACTTAGGAACTAAAAAAGGCTATACTATCAAAGAA
    ATCTTTAACTTAGGAACTAAAAAAGGCTATACTATCAAAGAAATCTTTAAAACTGCTGAA
    GAATTACTAAATTAA
    60
    120
    180
    195

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: HMPREF0837_12092 [new locus tag: HMPREF0837_RS10030 ]
  • symbol: HMPREF0837_12092
  • description: hypothetical protein
  • length: 64
  • theoretical pI: 9.75327
  • theoretical MW: 7389.47
  • GRAVY: -0.482812

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Sugars UDP-glucose 4-epimerase GalE (TIGR01179; EC 5.1.3.2; HMM-score: 26)
  • TheSEED  :
    • UDP-glucose 4-epimerase (EC 5.1.3.2)
    Carbohydrates Di- and oligosaccharides Lactose and Galactose Uptake and Utilization  UDP-glucose 4-epimerase (EC 5.1.3.2)
    and 2 more
    Cell Wall and Capsule Capsular and extracellular polysacchrides Rhamnose containing glycans  UDP-glucose 4-epimerase (EC 5.1.3.2)
    Protein Metabolism Protein processing and modification N-linked Glycosylation in Bacteria  UDP-glucose 4-epimerase (EC 5.1.3.2)
  • PFAM:
    no clan defined RPAP1_C; RPAP1-like, C-terminal (PF08620; HMM-score: 28.6)
    and 5 more
    ExoX-like_C; Exodeoxyribonuclease X-like C-terminal (PF20600; HMM-score: 17.8)
    DUF1413; Domain of unknown function (DUF1413) (PF07205; HMM-score: 13.3)
    DUF5338; Family of unknown function (DUF5338) (PF17273; HMM-score: 13.3)
    KH (CL0007) KH_1; KH domain (PF00013; HMM-score: 13.1)
    no clan defined DUF6199; Family of unknown function (DUF6199) (PF19701; HMM-score: 12)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.24
    • Cytoplasmic Membrane Score: 0.05
    • Cellwall Score: 0.8
    • Extracellular Score: 8.91
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.4954
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.504
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.055892
    • TAT(Tat/SPI): 0.000969
    • LIPO(Sec/SPII): 0.004686
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADI70320 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNYLFQEDSSSQIFNLGTKKGYTIKEIFNLGTKKGYTIKEIFNLGTKKGYTIKEIFKTAEELLN

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]