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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_RS08385 [old locus tag: HMPREF0837_11754 ]
  • pan locus tag?: PNEUPAN002803000
  • symbol: HMPREF0837_RS08385
  • pan gene symbol?: —
  • synonym:
  • product: GNAT family N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_RS08385 [old locus tag: HMPREF0837_11754 ]
  • symbol: HMPREF0837_RS08385
  • product: GNAT family N-acetyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1605704..1606168
  • length: 465
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014251 (1605704..1606168) NCBI
  • BioCyc: HMPREF0837_RS08385 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1348 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGAAATTCCAATTAAGATCATTCAGGCAAGCAAGTTTGATTTGCCTGAGATAGGGGCA
    CTTCAGACCTCGTCTTTTCCAGCTGAAAAGCAGCAACTTTCCCATATTTTAGAAGAAAGT
    ATCCGTAAGTGTGCGGATACCTTTCTTCTAGCTAGGGATGAAAATCAACTTTTAGGCTAT
    ATTTTATCAAGTCCCCAGTCAGACAATCCGCAATGTCTAAAAGTACATTCTTTAGTCATC
    GAGTCTGACCATCAGAGACAGGGCCTGGGAACACTTCTTCTTGCAGCCTTGAAAGAGGTG
    GCAGTTGAGCTGGATTACAAAGGGATTCGTTTGGAGAGTCCTGATGAGCTGCTTTCCTAT
    TTTGAAATGAACGGTTTTGTTGATGAAGAAGAAACTTTGCTCTATGCAACTAGCCAGGGC
    TATAGTATGATTTGGTTTAATCCCTTTTATCTGGAGGAACAATGA
    60
    120
    180
    240
    300
    360
    420
    465

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_RS08385 [old locus tag: HMPREF0837_11754 ]
  • symbol: HMPREF0837_RS08385
  • description: GNAT family N-acetyltransferase
  • length: 154
  • theoretical pI: 4.15672
  • theoretical MW: 17514.8
  • GRAVY: -0.181169

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.1.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 35.3)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 13.8)
    Cellular processes Cellular processes Adaptations to atypical conditions diaminobutyrate acetyltransferase (TIGR02406; EC 2.3.1.178; HMM-score: 13.1)
  • TheSEED: see HMPREF0837_11754
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 49.5)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 40.7)
    and 3 more
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 29.1)
    FR47; FR47-like protein (PF08445; HMM-score: 12.8)
    PH (CL0266) hSac2; Inositol phosphatase (PF12456; HMM-score: 11.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9712
    • Cytoplasmic Membrane Score: 0.0094
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0192
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003306
    • TAT(Tat/SPI): 0.0004
    • LIPO(Sec/SPII): 0.000574
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000405268 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKCADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAVELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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