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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-AUG-2013

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_00202 [new locus tag: HMPREF1038_RS00980 ]
  • pan locus tag?: PNEUPAN000806000
  • symbol: HMPREF1038_00202
  • pan gene symbol?: —
  • synonym:
  • product: IS1193, transposase, ISL3 family

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_00202 [new locus tag: HMPREF1038_RS00980 ]
  • symbol: HMPREF1038_00202
  • product: IS1193, transposase, ISL3 family
  • replicon: chromosome
  • strand: -
  • coordinates: 166498..167532
  • length: 1035
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001845 (166498..167532) NCBI
  • BioCyc: see HMPREF1038_RS00980
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    GTGGGTAATCCCACCCCAGGAATTATAGGGTCGTTTCTTGTAGAAAAAAAGCCCCATATG
    ACCTATAATGAAAAGCGTCTAACCAACTCATTAGAAAGGGTTCATATGGAACAACTTAAG
    AATACCACAGATTTGCTCGGATTGGAAGACAAAAATATCAAAATCTTGTCTGTTCTGAAA
    TACCAAACCCATCTAGTCGTTCAGGCAAAGTTGGATTCCCCCGCTCCTCCTTGTCCTCAT
    TGTCAAGGGAAGATGATCAAATACGACTTCCAGAAAGCCTCTAAAATTCCGCTTCTCGAC
    TGTCAGGGTTTACCCACGGTACTGCATCTCAAAAAGCGCCGCTTTCAGTGCAAGAATTGC
    CTTAAGGTGGTCGTTTCTCAAACATCCATTGTCAAGAAAAATTGCCAGATTTCCAACATG
    GTGAGACAAAAAATCGCTCAGCTCCTCCTTGAAAAGCAGTCTATGACTGAGATTGCCCAC
    AGATTGGCGGGCTCAACTTCCACCGTCATCCGAAAACTGAGGGAATTTAAGTTTGAAACC
    GATTGGACCAAGTTGCCAAAAGTTATGAGTTGGGATGAGTATAGCTTCAAAAAGAGCAAA
    ATGAGCTTCATTGCCCAAGATTTTGAGTCCAAATCCATCCTCGCAATTTTAGACGGACGA
    ACTCATGCGGTGATTCGAAACCATTTCCAACGCTATCAGAGAGAGGTTCGGGAGCTGGTC
    GAGGTCATCACCATGGACATGTACAGCCCTTATTATCGGCTCGCTAAGCAACTCTTTCCA
    AAGGCGAAGATTGTTCTTGACCGCTTCCACATTGTCCAACATCTGAGCCGAGCTATGAAC
    CGAGTACGAATCCAAATCATGAACCAATTTGACCGAAAATCCTTGGAGTATCGGGCGCTC
    AAGCGCTTTTGGAACCCTCGCTTTTTCGTTTCTAGGCTCGGGCTAAATCAGTCCACTGGA
    CTGATTTACTACACCAGGATAGCTTCAAGCTCTGTCAGAAACGATTCTATCAGCCCACGT
    TTCGAATGCACTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1035

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF1038_00202 [new locus tag: HMPREF1038_RS00980 ]
  • symbol: HMPREF1038_00202
  • description: IS1193, transposase, ISL3 family
  • length: 344
  • theoretical pI: 10.6262
  • theoretical MW: 40247
  • GRAVY: -0.397093

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Sporulation and germination RNA polymerase sigma-H factor (TIGR02859; HMM-score: 12.8)
    Genetic information processing Transcription Transcription factors RNA polymerase sigma-H factor (TIGR02859; HMM-score: 12.8)
    Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 11.3)
  • TheSEED  :
    • Mobile element protein
  • PFAM:
    RNase_H (CL0219) DDE_Tnp_ISL3; Transposase (PF01610; HMM-score: 94.8)
    and 12 more
    Zn_Beta_Ribbon (CL0167) zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 41.6)
    HTH (CL0123) HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 37.2)
    HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 20)
    HTH_50; Helix-turn-helix domain (PF18024; HMM-score: 19.4)
    Zn_Beta_Ribbon (CL0167) Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 15.7)
    HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 15.7)
    l-integrase_N (CL0469) Phage_int_SAM_2; Phage integrase, N-terminal (PF12834; HMM-score: 14.1)
    Zn_Beta_Ribbon (CL0167) Ogr_Delta; Ogr/Delta-like zinc finger (PF04606; HMM-score: 12.7)
    CDA (CL0109) Pput2613-deam; Pput_2613-like deaminase (PF14427; HMM-score: 12.7)
    Peroxisome (CL0484) Reticulon; Reticulon (PF02453; HMM-score: 12.1)
    Zn_Beta_Ribbon (CL0167) Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 12.1)
    Beta-tent (CL0080) Yippee-Mis18; Yippee zinc-binding/DNA-binding /Mis18, centromere assembly (PF03226; HMM-score: 10.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8142
    • Cytoplasmic Membrane Score: 0.0189
    • Cell wall & surface Score: 0.0227
    • Extracellular Score: 0.1443
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004595
    • TAT(Tat/SPI): 0.000188
    • LIPO(Sec/SPII): 0.000779
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFS42283 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGNPTPGIIGSFLVEKKPHMTYNEKRLTNSLERVHMEQLKNTTDLLGLEDKNIKILSVLKYQTHLVVQAKLDSPAPPCPHCQGKMIKYDFQKASKIPLLDCQGLPTVLHLKKRRFQCKNCLKVVVSQTSIVKKNCQISNMVRQKIAQLLLEKQSMTEIAHRLAGSTSTVIRKLREFKFETDWTKLPKVMSWDEYSFKKSKMSFIAQDFESKSILAILDGRTHAVIRNHFQRYQREVRELVEVITMDMYSPYYRLAKQLFPKAKIVLDRFHIVQHLSRAMNRVRIQIMNQFDRKSLEYRALKRFWNPRFFVSRLGLNQSTGLIYYTRIASSSVRNDSISPRFECT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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