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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
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A66
serotype 3
AP200
serotype 11A
ASP0581
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ATCC 49619
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ATCC 700669
serotype 23F
BM6001
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BVJ1JL
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CGSP14
serotype 14
G54
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HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-AUG-2013

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_01585 [new locus tag: HMPREF1038_RS07750 ]
  • pan locus tag?: PNEUPAN003001000
  • symbol: HMPREF1038_01585
  • pan gene symbol?: MFS
  • synonym:
  • product: major facilitator superfamily transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_01585 [new locus tag: HMPREF1038_RS07750 ]
  • symbol: HMPREF1038_01585
  • product: major facilitator superfamily transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 1453263..1454327
  • length: 1065
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGTTTGACTATTATCAGGGTTATTCTAAGGAACAAATTGAGCTCTTGGTGAGCTTGCCT
    TCCTTTGGAATCATGATGATGTTACTGCTAAATGGTTTCTTAGAAAAAATATTTCCTGAG
    CGCTTACAGATTAGTTTGGGCTTGCTGATTTTATCATTGAGCGGTACAGCTCCCTTCTGG
    TACCAAGCCTATCCCTTTGTCTTTGGAACACGGCTTCTCTTTGGTTTGGGTCTTGGGATG
    ATCAATGCCAAGGCCATTTCTATTATCAGTGAACGCTACCAAGGAAAAAGGCGAATTCAG
    ATGTTAGGGCTACGCGCTTCTGCAGAGGTCGTTGGAGCTTCTCTCATTACCTTGGCCGTC
    GGTCAGTTGTTGGCCTTTGGTTGGACAGCTATCTTTCTAGCCTATAGTGCTGGATTTTTG
    GTGCTGCCCCTTTATCTGCTCTTTGTCCCTTATGGAAAATCAAAGAAAGAAGTCAAGAAA
    AGAGCGAAGGAAGCAAGTCGTTTAACTCGAGAAATGAAAGGCTTGATTTTTACCTTAGCT
    ATCGAAGCGGCAGTTGTAGTTTGTACCAATACAGCTATTACCATCCGTATTCCAAGTTTG
    ATGGTGGAAAGAGGATTGGGGGATGCCCAGTTATCTAGTTTTGTTCTTAGTATCATGCAG
    TTGATCGGGATTGTGGCTGGGGTGAGTTTTTCTTTCTTGATTTCTATCTTTAAAGAGAAA
    CTGCTCCTCTGGTCTGGTATTACCTTTGGCTTGGGGCAAATCGTGATTGCCTTGTCTTCA
    TCCTTGTGGGTGGTAGTAGCAGGAAGTGTTCTGGCTGGATTTGCCTATAGTGTAGTCTTG
    ACGACGGTCTTTCAACTTGTCTCTGAACGAATTCCAGCTAAACTCCTCAATCAAGCAACT
    TCATTTGCTGTATTAGGCTGTAGTTTCGGAGCCTTTACGACCCCATTCGTTCTAGGTGCA
    ATTGGCTTACTAACTCACAATGGGATGTTGGTCTTTAGTATCTTAGGAGGTTGGTTGATT
    GTAATCTCTATCTTTGTCATGTACCTACTTCAGAAGAGAGCTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1065

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF1038_01585 [new locus tag: HMPREF1038_RS07750 ]
  • symbol: HMPREF1038_01585
  • description: major facilitator superfamily transporter
  • length: 354
  • theoretical pI: 10.2698
  • theoretical MW: 38607.1
  • GRAVY: 0.893503

⊟Function[edit | edit source]

  • TIGRFAM:
    multidrug resistance protein (TIGR00880; HMM-score: 37.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 32.5)
    and 7 more
    Metabolism Transport and binding proteins Anions Na(+)-dependent inorganic phosphate cotransporter (TIGR00894; HMM-score: 25.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 23.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, sugar porter (SP) family (TIGR00879; HMM-score: 19.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids monocarboxylate transporter (TIGR00892; HMM-score: 16.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 10.5)
    Cellular processes Cellular processes Toxin production and resistance drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 3)
    Metabolism Transport and binding proteins Other drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 3)
  • TheSEED  :
    • Uncharacterized MFS-type transporter
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 87)
    and 1 more
    no clan defined DUF1440; Protein of unknown function (DUF1440) (PF07274; HMM-score: 11.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003289
    • TAT(Tat/SPI): 0.000205
    • LIPO(Sec/SPII): 0.003814
  • predicted transmembrane helices (TMHMM): 11

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFS43610 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFDYYQGYSKEQIELLVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLLFGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAIFLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCTNTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGITFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVLGCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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