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serotype 4
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serotype 2
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serotype 19A
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serotype 6B
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70585
serotype 5
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serotype 19F
A66
serotype 3
AP200
serotype 11A
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serotype 19F
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serotype 23F
BM6001
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HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-AUG-2013

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_01726 [new locus tag: HMPREF1038_RS08475 ]
  • pan locus tag?: PNEUPAN003178000
  • symbol: HMPREF1038_01726
  • pan gene symbol?: yhbY
  • synonym:
  • product: conserved hypothetical RNA-binding protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_01726 [new locus tag: HMPREF1038_RS08475 ]
  • symbol: HMPREF1038_01726
  • product: conserved hypothetical RNA-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1594362..1594673
  • length: 312
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGTCATTAACATCAAAACAACGTGCCTTCCTCAACAGCCAGGCACACACCCTCAAACCT
    ATCATCCAAATCGGGAAAAATGGACTCAACGACCAAATCAAAACCAGCGTCCGTCAAGCT
    CTTGATGCGCGTGAATTAATCAAGGTTACTCTCTTACAAAACACAGATGAAAATATCCAC
    GAAGTAGCTGAAATTTTGGAAGAAGAAATCGGTGTGGATACAGTCCAAAAAATAGGACGC
    ATCTTGATTTTGTTTAAACAATCTAGCAAGAAAGAAAATCGCAAGATTTCTAAGAAAGTC
    AAAGAAATCTAA
    60
    120
    180
    240
    300
    312

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: HMPREF1038_01726 [new locus tag: HMPREF1038_RS08475 ]
  • symbol: HMPREF1038_01726
  • description: conserved hypothetical RNA-binding protein
  • length: 103
  • theoretical pI: 10.4432
  • theoretical MW: 11704.5
  • GRAVY: -0.437864

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General putative RNA-binding protein, YhbY family (TIGR00253; HMM-score: 86.8)
  • TheSEED  :
    • RNA-binding protein YhbY
  • PFAM:
    no clan defined CRS1_YhbY; CRS1 / YhbY (CRM) domain (PF01985; HMM-score: 74.8)
    and 4 more
    GME (CL0197) PAD; Protein-arginine deiminase (PAD) (PF03068; HMM-score: 17.8)
    ACT (CL0070) NikR_C; NikR C terminal nickel binding domain (PF08753; HMM-score: 15.4)
    no clan defined CytochromB561_N; Cytochrome B561, N terminal (PF09786; HMM-score: 14.5)
    HTH (CL0123) Fe_dep_repr_C; Iron dependent repressor, metal binding and dimerisation domain (PF02742; HMM-score: 13.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.93
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0695
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001337
    • TAT(Tat/SPI): 0.000694
    • LIPO(Sec/SPII): 0.000237
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFS43750 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDARELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKEI

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]