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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_RS06565 [old locus tag: HMPREF1038_01343 ]
  • pan locus tag?: PNEUPAN002698000
  • symbol: HMPREF1038_RS06565
  • pan gene symbol?: trzA
  • synonym:
  • product: TRZ/ATZ family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_RS06565 [old locus tag: HMPREF1038_01343 ]
  • symbol: HMPREF1038_RS06565
  • product: TRZ/ATZ family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1237046..1238305
  • length: 1260
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018630 (1237046..1238305) NCBI
  • BioCyc: HMPREF1038_RS06565 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1190 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAAGTCTTTCAGCATGTAAATATCGTGACTTGTGATCAAAATTTCCATGTTTATCTT
    GATGGAATCTTAGCAGTCAAGGATTCTCAAATCGTCTATGTCGGTCAAGATAAGCCAGCG
    TTTTTAGAACAAGCTGAGCAGATTGTAGACTATCAGGGAGCTTGGATTATGCCTGGTTTG
    GTCAATTGTCACACCCATTCTGCAATGACAGGTCTGAGAGGGATCCGAGATGACAGCAAT
    CTCCATGAATGGCTCAATGACTATATCTGGCCAGCAGAATCTGAGTTTACTCCCGACATG
    ACTACCAATGCGGTCAAAGAAGCCTTGACAGAGATGCTCCAGTCAGGAACAACAACCTTT
    AACGATATGTATAATCCCAGTGGTGTGGATATCCAGCAAATTTATCAGGTGGTGAAAACT
    TCCAAGATGCGTTGTTATTTTTCTCCGACTCTCTTTTCTTCAGAGACAGAAACAACTGCT
    GAGACTATAAGCAGAACTCGATCCATCATAGATGAAATCTTAAAATATAAAAATCCAAAT
    TTCAAGGTTATGGTAGCACCTCATTCTCCGTATAGCTGCAGTAGAGACTTGCTGGAAGCG
    AGTTTGGAAATGGCAAAAGAGCTAAATATTCCGCTCCATGTCCATGTGGCGGAGACCAAG
    GAGGAGTCAGGAATTATCCTCAAACGATACGGCAAACGCCCCCTTGCTTTTCTTGAAGAA
    CTGGGTTATTTAGATCATCCGTCCGTATTTGCTCACGGGGTCGAATTAAACGAGAGAGAA
    ATTGAACGCTTGGCATCTTCTCAAGTGGCTATCGCCCACAATCCTATCAGTAACCTCAAA
    CTGGCATCAGGAATTGCTCCAATTATCCAGCTCCAAAAAGCGGGAGTAGCAGTCGGAATT
    GCGACTGACTCGGTTGCTTCCAATAACAATCTAGATATGTTTGAGGAAGGAAGGACTGCA
    GCTCTTCTTCAGAAGATGAAAAGTGGGGATGCCAGCCAGTTTCCAATCGAAACAGCTCTC
    AAGGTACTGACAATCGAAGGGGCTAAGGCCCTTGGAATGGAAAATCAGATAGGAAGTCTG
    GAAGTCGGCAAGCAAGCAGATTTTCTGGTCATTCAACCACAAGGGAAAATTCATCTCCAA
    CCTCAGGAAAATATGCTGTCTCACCTGGTTTATGCAGTTAAATCTAGTGATGTAGATGAT
    GTTTATATCGCCGGAGAACAGGTTGTTAAGCAAGGTCAAGTCCTGACAGTAGAACTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF1038_RS06565 [old locus tag: HMPREF1038_01343 ]
  • symbol: HMPREF1038_RS06565
  • description: TRZ/ATZ family protein
  • length: 419
  • theoretical pI: 4.90108
  • theoretical MW: 46466.6
  • GRAVY: -0.154654

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other guanine deaminase (TIGR02967; EC 3.5.4.3; HMM-score: 192)
    and 14 more
    putative selenium metabolism protein SsnA (TIGR03314; HMM-score: 151.6)
    Metabolism Energy metabolism Amino acids and amines formiminoglutamate deiminase (TIGR02022; EC 3.5.3.13; HMM-score: 139.5)
    Metabolism Energy metabolism Amino acids and amines imidazolonepropionase (TIGR01224; EC 3.5.2.7; HMM-score: 72.5)
    allantoinase (TIGR03178; EC 3.5.2.5; HMM-score: 44.2)
    Metabolism Energy metabolism Other phosphonate metabolism protein PhnM (TIGR02318; HMM-score: 40.1)
    dihydropyrimidinase (TIGR02033; EC 3.5.2.2; HMM-score: 33.9)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine deaminase (TIGR01178; EC 3.5.4.2; HMM-score: 27)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis dihydroorotase, multifunctional complex type (TIGR00857; EC 3.5.2.3; HMM-score: 25.6)
    Metabolism Central intermediary metabolism Amino sugars N-acetylglucosamine-6-phosphate deacetylase (TIGR00221; EC 3.5.1.25; HMM-score: 25.5)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides beta-aspartyl peptidase (TIGR01975; EC 3.4.19.5; HMM-score: 23.8)
    formylmethanofuran dehydrogenase subunit A (TIGR03121; EC 1.2.99.5; HMM-score: 23.8)
    Metabolism Central intermediary metabolism Nitrogen metabolism urease, alpha subunit (TIGR01792; EC 3.5.1.5; HMM-score: 19.1)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions conjugative transfer region lipoprotein, TIGR03751 family (TIGR03751; HMM-score: 13.1)
    adenosine deaminase (TIGR01430; EC 3.5.4.4; HMM-score: 12.2)
  • TheSEED: see HMPREF1038_01343
  • PFAM:
    Amidohydrolase (CL0034) Amidohydro_1; Amidohydrolase family (PF01979; HMM-score: 231.4)
    and 2 more
    Amidohydro_3; Amidohydrolase family (PF07969; HMM-score: 83.1)
    TatD_DNase; TatD related DNase (PF01026; HMM-score: 21.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006132
    • TAT(Tat/SPI): 0.000147
    • LIPO(Sec/SPII): 0.000595
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_078150112 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQAEQIVDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTTNAVKEALTEMLQSGTTTFNDMYNPSGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTAETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAETKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPISNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQFPIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYAVKSSDVDDVYIAGEQVVKQGQVLTVEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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