PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 04-FEB-2016

⊟Summary

• organism: Streptococcus pneumoniae INV104
• locus tag: INV104_09850 [new locus tag: INV104_RS05710 ]
• pan locus tag^?: PNEUPAN002276000
• symbol: INV104_09850
• pan gene symbol^?: —
• synonym:
• product: Phage replication protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: INV104_09850 [new locus tag: INV104_RS05710 ]
• symbol: INV104_09850
• product: Phage replication protein
• replicon: chromosome
• strand: +
• coordinates: 1075692..1076477
• length: 786
• essential: unknown

⊟Accession numbers

• Location: FQ312030 (1075692..1076477) NCBI
• BioCyc: see INV104_RS05710
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  
  GTGGGGTGGAATGAGAACGGAGAGGTAATAAAAGAAGTTCGCTGTATCCCACCCTATTGT
  GAACAATGCCAAGAAGAACAGAAAAAGCAAGATGAAGAAGATGCGATTGCTGATAATTTG
  AATGCTAAACTATATCTGCAAACTTATAATGTGTTGATGAGCAATAAGAGCTATGTAGCA
  GATGAGTTTAAAACTAAAACTTTTGATGATTTTAATGCTGTAACATCAGAAGAAAAGCGA
  TTTTTAGAATTTGCAAAAGGTCAGGTACAAAAATATCTTGATGGCATGAGGGGAAATACG
  CTTATCACAGGAGGTACAGGGATTGGAAAAACACTTTTATCAGTTGCTATTGCCAAAGGT
  ATAAATGAGGGGTATAAGACAAAAGGAGAACCTAAGAGTGTGCTTTTTGTAAGCCTAACC
  GAAATGATCAAACAAATTAAAGAGGGGTGGAATTATGGTAAAGGTGCAACACTTACAGAG
  TTTGAAGCTACTGAACTCATGAAGTCTGTTGATTACTTAATTATTGATGATTTAGGTGCA
  AAAAATGCTGTTATTAAACCTAAGAGCGATTGGGAGCAGGATTTACTTTTTGATGTACTG
  AATAATCGAGAAAATACTATATTTAATACAAATCTTGATAGCGATGAACTCAAGATAGTA
  TACAACGAGCGGAATTATAGCCGTATTCTAAAAGGTCTTGAGGGTAACACTTTTAAGGCT
  TTCACAATCAAAGATAAGCGATACTCAATTAATCAGTTAAAAAATAAGGTAAAGCAGTTG
  AAGTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  786
  

⊟Protein

⊟General

• locus tag: INV104_09850 [new locus tag: INV104_RS05710 ]
• symbol: INV104_09850
• description: Phage replication protein
• length: 261
• theoretical pI: 5.31214
• theoretical MW: 29811.7
• GRAVY: -0.605364

⊟Function

• TIGRFAM:
  Genetic information processing DNA metabolism DNA replication, recombination, and repair chromosomal replication initiator protein DnaA (TIGR00362; HMM-score: 29.7)
  and 4 more
  Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides ATP-dependent Clp protease, ATP-binding subunit ClpX (TIGR00382; HMM-score: 12.7)
  Genetic information processing Protein fate Protein folding and stabilization ATP-dependent Clp protease, ATP-binding subunit ClpX (TIGR00382; HMM-score: 12.7)
  Cellular processes Cellular processes Conjugation P-type conjugative transfer ATPase TrbB (TIGR02782; HMM-score: 12.2)
  helicase/secretion neighborhood ATPase (TIGR03819; HMM-score: 10.5)
• TheSEED  :
  • DNA replication protein DnaC
  DNA Metabolism DNA replication DNA-replication  DNA replication protein DnaC
• PFAM:
  P-loop_NTPase (CL0023) IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 37.5)
  and 11 more
  Bac_DnaA; Bacterial dnaA protein (PF00308; HMM-score: 22.4)
  ATPase; KaiC (PF06745; HMM-score: 21.8)
  T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 19.7)
  ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 18.3)
  DEAD; DEAD/DEAH box helicase (PF00270; HMM-score: 17.5)
  NACHT; NACHT domain (PF05729; HMM-score: 17.3)
  AAA_22; AAA domain (PF13401; HMM-score: 16)
  no clan defined DUF6447; Family of unknown function (DUF6447) (PF20045; HMM-score: 14.5)
  P-loop_NTPase (CL0023) AAA_19; AAA domain (PF13245; HMM-score: 14.4)
  DUF2075; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 13.2)
  RNA_helicase; RNA helicase (PF00910; HMM-score: 12.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.8353
  • Cytoplasmic Membrane Score: 0.0625
  • Cell wall & surface Score: 0.0009
  • Extracellular Score: 0.1014
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005161
  • TAT(Tat/SPI): 0.000288
  • LIPO(Sec/SPII): 0.001875
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: CBW36667 NCBI
• UniProt:

⊟Protein sequence

• MGWNENGEVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKTKTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINEGYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAKNAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFKAFTIKDKRYSINQLKNKVKQLK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications