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serotype 1
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serotype 14
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TCH8431/19A
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Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-FEB-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV104
  • locus tag: INV104_10980 [new locus tag: INV104_RS06320 ]
  • pan locus tag?: PNEUPAN002529000
  • symbol: carA
  • pan gene symbol?: carA
  • synonym:
  • product: carbamoyl-phosphate synthase small chain

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: INV104_10980 [new locus tag: INV104_RS06320 ]
  • symbol: carA
  • product: carbamoyl-phosphate synthase small chain
  • replicon: chromosome
  • strand: -
  • coordinates: 1210176..1211255
  • length: 1080
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGACAAAAAGAATTCTAGTATTAGAAGATGGCACAGTTTTTGAAGGCAAGGCCTTCGGA
    GCAGATATTGATGTAACAGGCGAAATCGTCTTTAATACAGGGATGACCGGCTACCAAGAA
    TCCATTACAGACCAGTCTTATAATGGACAAATCTTGACCTTTACTTATCCTTTGGTAGGA
    AATTATGGTATTAATCGTGATGATTATGAATCCATTATTCCAACTTGTAAGGGAGTCGTT
    GTTTTTGAAGAAGCGCGTAGAGCTAGCAACTGGCGCAACCAAATGACCTTGGATGAATTT
    TTGAAAGCCAAGAAAATTCCAGGGATTTCAGGAATTGATACGCGTGCTCTTACCAAGATT
    ATCCGTAAGCATGGTACTATGCGTGCAACCTTGACCCATGTTGGGGACAGTATGGACCAT
    GTGACGGACCAGCTCCAAGCAACAGTTTTACCGACAGACAATATCAAACAGGTTTCTACT
    AAAACGTCTTATCCAGCTCCAGGAGTTGGTTTGAGCGTGGTGCTAGTGGACTTTGGTCTC
    AAGCACTCAATCCTACGTGAACTTTCTAAACGCAACTGTAACGTGACAGTTGTTCCTTAT
    TCGACAACGGCTGAAGAAATTCTCCATCTCAATCCTGATGGAGTTATGTTGTCAAATGGT
    CCAGGTAACCCAGAAGACGTTCCACAAGCACTCGACATGATTCGCGGTGTACAAGGAAAA
    ATTCCAATCTTTGGTATTTGTATGGGACACCAACTCTTTGCAATGGCAAACGGGGCTAAG
    ACCTATAAGATGAAGTTTGGCCACCGTGGATTCAACCATGCGGTACGTGAAATCGCAACA
    GGACGAGTAGACTTCACCAGCCAGAACCATGGTTATGCAGTCAGCCGCGAGGATTTGCCA
    GAGCACTTGATTATTACCCACGAAGAAATCAATGACAAGTCAGTGGAAGGTGTGCGCCAC
    AGATACCAACCTGCTTTCTCTGTTCAATACCACCCAGATGCAGCTCCTGGGCCACACGAC
    GCTAGCTACCTATTTGACGAGTTTATCGAGATGATGGAAGTTTTTAAACAATCAAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: INV104_10980 [new locus tag: INV104_RS06320 ]
  • symbol: CarA
  • description: carbamoyl-phosphate synthase small chain
  • length: 359
  • theoretical pI: 6.39342
  • theoretical MW: 39863
  • GRAVY: -0.295543

⊟Function[edit | edit source]

  • reaction:
    EC 6.3.5.5?  ExPASy
    Carbamoyl-phosphate synthase (glutamine-hydrolyzing) 2 ATP + L-glutamine + HCO3(-) + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate
  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis carbamoyl-phosphate synthase, small subunit (TIGR01368; EC 6.3.5.5; HMM-score: 483)
    and 5 more
    glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase (TIGR00566; HMM-score: 74.9)
    Metabolism Amino acid biosynthesis Aromatic amino acid family anthranilate synthase (TIGR01815; EC 4.1.3.27; HMM-score: 61.4)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis GMP synthase (glutamine-hydrolyzing), N-terminal domain (TIGR00888; EC 6.3.5.2; HMM-score: 59.2)
    aminodeoxychorismate synthase (TIGR01823; EC 2.6.1.85; HMM-score: 55.4)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis CTP synthase (TIGR00337; EC 6.3.4.2; HMM-score: 12.6)
  • TheSEED  :
    • Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
    Nucleosides and Nucleotides Pyrimidines De Novo Pyrimidine Synthesis  Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
  • PFAM:
    Leu-IlvD (CL0364) CPSase_sm_chain; Carbamoyl-phosphate synthase small chain, CPSase domain (PF00988; HMM-score: 177)
    Glutaminase_I (CL0014) GATase; Glutamine amidotransferase class-I (PF00117; HMM-score: 161.4)
    and 2 more
    Peptidase_C26; Peptidase C26 (PF07722; HMM-score: 28.1)
    MBB (CL0193) LptD_2; LptD protein (PF19838; HMM-score: 11.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9831
    • Cytoplasmic Membrane Score: 0.0054
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0112
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02269
    • TAT(Tat/SPI): 0.000669
    • LIPO(Sec/SPII): 0.001806
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW36779 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITDQSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLKAKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVSTKTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLSNGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVREIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDAAPGPHDASYLFDEFIEMMEVFKQSN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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