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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV104
  • locus tag: INV104_RS06750 [old locus tag: INV104_11770 ]
  • pan locus tag?: PNEUPAN002707000
  • symbol: INV104_RS06750
  • pan gene symbol?: amy
  • synonym:
  • product: alpha-amylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: INV104_RS06750 [old locus tag: INV104_11770 ]
  • symbol: INV104_RS06750
  • product: alpha-amylase
  • replicon: chromosome
  • strand: +
  • coordinates: 1289619..1291073
  • length: 1455
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017591 (1289619..1291073) NCBI
  • BioCyc: INV104_RS06750 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1215 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAAAATCAAACACTCATGCAATACTTTGAATGGTATCTGCCCCACGACGGTCAACAC
    TGGACGCGTCTGGCTGAAAATGCTCCACACCTAGCTCATCTGGGGATCAGTCACGTCTGG
    ATGCCACCAGCCTTCAAGGCAACCAACGAAAAAGATGTCGGCTATGGGGTCTATGACTTA
    TTTGACTTAGGAGAGTTCAACCAAAAAGGGACTGTCCGCACCAAGTATGGTTTCAAAGAA
    GACTATCTTCAAGCCATTCAAGCCCTTAAAGAACAGGGAATTCAACCTATGGCCGATGTA
    GTTCTCAACCACAAGGCTGCTGCCGATAACAGGGAAGCCTTTCAGGTTATCGAAGTTGAT
    CCTGTAGACCGTACAGTTGAACTTGGAGAACCCTTCACCATCAATGGCTGGACTAGTTTT
    ACCTTCGATGGTCGCCAAGATACCTATAATGGCTTCCACTGGCATTGGTACCACTTCACC
    GGTACAGACTACGATGCCAAACGCAGTAAATCTGGGATTTATCTGATCCAAGGGGACAAC
    AAGGGCTGGGCTAACGAGGAATTGGTCGATAACGAAAACGGAAACTACGACTACCTCATG
    TATGCCGACCTAGACTTTAAACATCCTGAAGTCATCCAAAACATCTATGACTGGGCTGAT
    TGGTTCATGGAAACGACTGGTGTAGCTGGTTTCCGTTTGGATGCCGTTAAGCATATTGAC
    TCTTTCTTTATGCGCAACTTCATCCGCGATATGAAGGAAAAATACGGTGACGATTTCTAT
    GTTTTTGGTGAATTTTGGAACCCAGACAAGGAAGCCAATCTGGACTATCTCGAAAAAACG
    GAAGAACACTTTGACCTTGTCGATGTTCGTCTCCACCAGAATCTCTTTGAAGCCAGTCAA
    GCTGGCGCAAACTATGACCTTCGTGGCATTTTCACAGATAGCCTGGTTGAACTCAAGCCT
    GACAAGGCTGTGACTTTTGTCGACAACCACGATACCCAACGAGGACAAGCCCTTGAGTCT
    ACCGTTGAAGAATGGTTCAAGCCAGCAGCCTATGCCCTCATTTTGTTACGCCAAGACGGC
    CTTCCATGTGTCTTTTACGGAGACTACTATGGGATTTCAGGCCAGTATGCTCAAGAAGAT
    TTCAAAGAAATCCTTGACCGCCTCCTAGCCATCCGAAAAGACTTGGCCTATGGAGAACAA
    AATGACTACTTTGACCATGCTAACTGTATCGGTTGGGTACGTTCAGGTGCTGAAAATCAA
    TCCCCAATCGCAGTCCTTATCTCAAATGACCAAGAAAACAGCAAGTCAATGTTTGTCGGT
    CAAGAATGGACTAATCAAACCTTTGTAGATTTACTTGGTAACCACCAAGGTCAAGTTACA
    ATTGATGAGGAAGGTTATGGACAATTCCCTGTCTCAGCTAGATCCGTAAGTGTCTGGGCA
    GTCAATACCATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1455

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: INV104_RS06750 [old locus tag: INV104_11770 ]
  • symbol: INV104_RS06750
  • description: alpha-amylase
  • length: 484
  • theoretical pI: 4.3711
  • theoretical MW: 55952.5
  • GRAVY: -0.541322

⊟Function[edit | edit source]

  • reaction:
    EC 3.2.1.1?  ExPASy
    Alpha-amylase Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units
  • TIGRFAM:
    alpha,alpha-phosphotrehalase (TIGR02403; EC 3.2.1.93; HMM-score: 45.6)
    and 4 more
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides malto-oligosyltrehalose synthase (TIGR02401; EC 5.4.99.15; HMM-score: 30.1)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides malto-oligosyltrehalose trehalohydrolase (TIGR02402; EC 3.2.1.141; HMM-score: 28.5)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen debranching enzyme GlgX (TIGR02100; EC 3.2.1.-; HMM-score: 19)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides alpha-1,6-glucosidases, pullulanase-type (TIGR02103; EC 3.2.1.41; HMM-score: 10.7)
  • TheSEED: see INV104_11770
  • PFAM:
    Glyco_hydro_tim (CL0058) Alpha-amylase; Alpha amylase, catalytic domain (PF00128; HMM-score: 115.3)
    and 2 more
    GHD (CL0369) Alpha-amy_C_pro; Alpha-amylase C-terminal (PF09154; HMM-score: 51.1)
    Glyco_hydro_tim (CL0058) Glyco_hydro_70; Glycosyl hydrolase family 70 (PF02324; HMM-score: 41.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.1
    • Cytoplasmic Membrane Score: 0.14
    • Cellwall Score: 0.15
    • Extracellular Score: 9.6
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016868
    • TAT(Tat/SPI): 0.000757
    • LIPO(Sec/SPII): 0.001168
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001181074 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPAFKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVLNHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFTGTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDWADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDYLEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQRGQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIRKDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVDLLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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