PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 08-APR-2025

⊟Summary

• organism: Streptococcus pneumoniae BVJ1JL
• locus tag: JN057_RS00200 [old locus tag: JN057_00041 ]
• pan locus tag^?: PNEUPAN000406000
• symbol: JN057_RS00200
• pan gene symbol^?: —
• synonym:
• product: phage replisome organizer N-terminal domain-containing protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JN057_RS00200 [old locus tag: JN057_00041 ]
• symbol: JN057_RS00200
• product: phage replisome organizer N-terminal domain-containing protein
• replicon: chromosome
• strand: +
• coordinates: 31183..32022
• length: 840
• essential: unknown

⊟Accession numbers

• Location: NZ_CP071871 (31183..32022) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  
  ATGTCTGAAATCAAGTGGATAAAAATCAAAACGGATATTTTTGACGATGAAAAGATGTGT
  CTAATTGATGCCTCGCCTGATCGTGATGCAATTATTGTAATCTGGATCAAACTTATAACA
  CTAGCAGGCAAATTGAATACAAAAGGCGTACTAACCATTTCTAAAAACATTGTATACACC
  GATGAAATGCTTGCACAAACGTTCCACCGTCCGTTGAATACAGTTCGTATGGCTCTTGAA
  GTTTTTGAAAAGTTTGGAATGGTTGAAAAAATCGATGGAGTGATAATGTTACCCAATTGG
  GAGAAACATCAGAACATTGACGGCATGGAAAAAATAAAAGAGCAAAATCGAAATAGAGCA
  GCACGTCACCGACAAAAACAGAAATTACTTGCACAGAACAACGAAAGTAACGTTACTGAT
  AACGTTATGGATAACGTTATGGATAACGTTACAGTAACGCATGGTAACGCACTAGATAAA
  GAATTAGATAAAGATATAGAGATAAATAATAATAAGGTGATGATTAGTTCCAGCCTTTCT
  GAAAATTTGAAAAATAGCGGAATCCATCTAACTGATAAGTCACATCAACAGTTACTTGAT
  TATGTGGGACTTGATGGAATGAGTTTCGATATGTTGAACCGTGCAGTCGAGAAAACTTCC
  GGATCACACAAACCTAGTTTCAATTACCTAATAGCCATTCTTGAAAGTTGGAAAAAGAAA
  GGCTTCACATCGATTGAGCAGGTGGATGAGGACGACCGTAAATATAAAGAGGGTAAGAAG
  TCAAGACAACAAAACGATAAAACATCGGAACAGGAGGTAAGGGACGAATGGGGATTTTAG
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⊟Protein

⊟General

• locus tag: JN057_RS00200 [old locus tag: JN057_00041 ]
• symbol: JN057_RS00200
• description: phage replisome organizer N-terminal domain-containing protein
• length: 279
• theoretical pI: 6.4151
• theoretical MW: 32173.4
• GRAVY: -0.662724

⊟Function

• TIGRFAM:
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage replisome organizer, putative, N-terminal region (TIGR01714; HMM-score: 121.6)
  and 3 more
  Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaD domain protein (TIGR01446; HMM-score: 48.9)
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions DnaD domain protein (TIGR01446; HMM-score: 48.9)
  Signal transduction Regulatory functions DNA interactions trehalose operon repressor (TIGR02404; HMM-score: 19.3)
• TheSEED: data available for Hungary19A-6
• PFAM:
  HTH (CL0123) Phage_rep_org_N; N-terminal phage replisome organiser (Phage_rep_org_N) (PF09681; HMM-score: 155)
  and 3 more
  no clan defined DnaB_2; Replication initiation and membrane attachment (PF07261; HMM-score: 42.1)
  G0-G1_switch_2; G0/G1 switch protein 2 (PF15103; HMM-score: 15.8)
  DUF6241; Family of unknown function (DUF6241) (PF19754; HMM-score: 15)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9884
  • Cytoplasmic Membrane Score: 0.0009
  • Cell wall & surface Score: 0.001
  • Extracellular Score: 0.0097
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002496
  • TAT(Tat/SPI): 0.00013
  • LIPO(Sec/SPII): 0.000388
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_061370840 NCBI
• UniProt:

⊟Protein sequence

• MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGKLNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEKHQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVMDNVTVTHGNALDKELDKDIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGSHKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications