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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BVJ1JL
  • locus tag: JN057_RS10315 [old locus tag: JN057_02114 ]
  • pan locus tag?: PNEUPAN003758000
  • symbol: JN057_RS10315
  • pan gene symbol?: gpsA
  • synonym:
  • product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JN057_RS10315 [old locus tag: JN057_02114 ]
  • symbol: JN057_RS10315
  • product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 1975032..1976048
  • length: 1017
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP071871 (1975032..1976048) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1918 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGAAAAACAAACCGTCGCCGTCTTGGGGCCTGGTTCTTGGGGAACCGCCCTTTCACAA
    GTCTTAAATGACAATGGACACGAGGTACGTATTTGGGGAAATCTTCCCGAGCAAATCAAT
    GAAATTAATACACACCATACTAATAAGCACTACTTTAAAGATGTCGTTCTAGACGAAAAT
    ATCATTGCCTACACCGACTTAGCAGAAACATTGAAAGATGTGGATGCGATTTTGTTTGTT
    GTCCCAACAAAAGTGACACGACTTGTTGCCCAGCAAGTTGCACAAACCTTGGACCATAAG
    GTTATCATCATGCACGCATCAAAGGGATTAGAACCTGATAGCCATAAACGATTATCAACC
    ATTCTTGAAGAAGAAATTCCTGAACATCTCCGTAGTGATATCGTCGTTGTTTCAGGGCCT
    AGTCATGCAGAAGAGACCATTGTGCGTGACCTAACTTTAATAACTGCTGCTTCTAAAGAT
    TTACAAACAGCTCAATACGTTCAGGAGCTATTTAGTAATCACTACTTCCGACTTTATACC
    AATACGGATGTTATCGGGGTTGAAACTGCTGGTGCTCTTAAAAATATTATTGCTGTCGGT
    GCTGGAGCTTTACATGGTCTTGGATTTGGTGATAATGCTAAGGCAGCCATCATCGCTCGA
    GGTTTAGCAGAAATCACCCGCCTAGGGGTAGCACTCGGGGCCAGTCCATTGACCTATAGC
    GGCTTATCTGGTGTGGGAGATTTGATCGTAACGGGAACTTCCATCCACTCTCGTAACTGG
    AGAGCTGGAGATGCTCTCGGACGAGGAGAATCCCTAGCTGATATAGAAGCTAATATGGGC
    ATGGTAATCGAAGGAATTTCAACGACTCGAGCAGCCTATGAACTAGCCCAAGAACTTGGA
    GTCTATATGCCCATTACACAGGCTATTTACCAAGTTATTTATCACGGAACCAATATCAAA
    GATGCCATTTATGACATCATGAACAATGAATTTAAAGCAGAAAATGAGTGGTCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1017

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JN057_RS10315 [old locus tag: JN057_02114 ]
  • symbol: JN057_RS10315
  • description: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
  • length: 338
  • theoretical pI: 4.96307
  • theoretical MW: 36777.3
  • GRAVY: -0.0272189

⊟Function[edit | edit source]

  • reaction:
    EC 1.1.1.94?  ExPASy
    Glycerol-3-phosphate dehydrogenase (NAD(P)+) sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H
  • TIGRFAM:
    glycerol-3-phosphate dehydrogenase (NAD(+)) (TIGR03376; EC 1.1.1.8; HMM-score: 219.1)
    and 4 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A 2-dehydropantoate 2-reductase (TIGR00745; EC 1.1.1.-; HMM-score: 28.5)
    nucleotide sugar dehydrogenase (TIGR03026; HMM-score: 23.4)
    Metabolism Energy metabolism Pentose phosphate pathway 6-phosphogluconate dehydrogenase (decarboxylating) (TIGR00872; EC 1.1.1.44; HMM-score: 15.6)
    3-hydroxyacyl-CoA dehydrogenase PaaC (TIGR02279; EC 1.1.1.-; HMM-score: 13.2)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus (PF01210; HMM-score: 181.2)
    6PGD_C (CL0106) NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus (PF07479; HMM-score: 175.8)
    and 11 more
    no clan defined GPD_NAD_C_bact; Bacterial GPD, NAD-dependent C-terminal (PF20618; HMM-score: 66.7)
    NADP_Rossmann (CL0063) ApbA; Ketopantoate reductase PanE/ApbA (PF02558; HMM-score: 29.5)
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase (PF03446; HMM-score: 27.4)
    F420_oxidored; NADP oxidoreductase coenzyme F420-dependent (PF03807; HMM-score: 24.2)
    IlvN; Acetohydroxy acid isomeroreductase, NADPH-binding domain (PF07991; HMM-score: 23.3)
    UDPG_MGDP_dh_N; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain (PF03721; HMM-score: 20.1)
    2-Hacid_dh_C; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (PF02826; HMM-score: 16.7)
    3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain (PF02737; HMM-score: 15.2)
    Semialdhyde_dh; Semialdehyde dehydrogenase, NAD binding domain (PF01118; HMM-score: 15)
    PDH_N; Prephenate dehydrogenase, nucleotide-binding domain (PF02153; HMM-score: 13)
    CoA_binding_2; CoA binding domain (PF13380; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9921
    • Cytoplasmic Membrane Score: 0.002
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0057
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.043816
    • TAT(Tat/SPI): 0.000982
    • LIPO(Sec/SPII): 0.026301
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000415102 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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