Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 08-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae BVJ1JL
- locus tag: JN057_RS10340 [old locus tag: JN057_02120 ]
- pan locus tag?: PNEUPAN003726000
- symbol: JN057_RS10340
- pan gene symbol?: ygfA
- synonym:
- product: 5-formyltetrahydrofolate cyclo-ligase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JN057_RS10340 [old locus tag: JN057_02120 ]
- symbol: JN057_RS10340
- product: 5-formyltetrahydrofolate cyclo-ligase
- replicon: chromosome
- strand: -
- coordinates: 1979281..1979820
- length: 540
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NZ_CP071871 (1979281..1979820) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_1921 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481ATGAAATCGGAATTACGCAAGCAAGTCTTGCATGAAATGAAGGCTATATCTCAAGAGCAA
AAACAGGCTATAGACCAAGCTTTAACCGAGCGGCTTTTACACCATCCCTTCTACCAAGAA
GCCAAGGTCATCGCAACCTACCTCTCTTTTTCTCATGAGTTTCAAACGCGGGAACTGATT
GAGCAGGCGCTGAAGGACGGCAAGAAGGTTTTAATGCCCAAAACTTATCCCAAGGGGCGC
ATGGACTTTGTGGTCTATGATCCGCAACAGTTGGTAAAAACTTCCTTTGCCTTACTGGAG
CCACAGGGAGATGTGGAAGTGGTGGATGCATCTCAGATTGATTTGATTCATGTTCCTGGT
CTGGCTTTTACGACGAAAGGATATCGGATAGGATACGGTGGAGGCTATTATGACCGCTAT
CTGGAACATTTTTCTGGTCATACTTTGAGTACGGTTCATCCTTGTCAAATTCAGGACTTT
ATACCTGAAAACCATGATATTCCTGTTCAGGAGGTATTAATTGATGAAGGAAATCTTTGA60
120
180
240
300
360
420
480
540
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JN057_RS10340 [old locus tag: JN057_02120 ]
- symbol: JN057_RS10340
- description: 5-formyltetrahydrofolate cyclo-ligase
- length: 179
- theoretical pI: 6.02159
- theoretical MW: 20543.3
- GRAVY: -0.4
⊟Function[edit | edit source]
- reaction: EC 6.3.3.2? ExPASy5-formyltetrahydrofolate cyclo-ligase ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate
- TIGRFAM: Central intermediary metabolism One-carbon metabolism 5-formyltetrahydrofolate cyclo-ligase (TIGR02727; EC 6.3.3.2; HMM-score: 178.3)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: ISOCOT_Fold (CL0246) 5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family (PF01812; HMM-score: 153.4)and 1 moreno clan defined DUF4790; Domain of unknown function (DUF4790) (PF16037; HMM-score: 12.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001513
- TAT(Tat/SPI): 0.000315
- LIPO(Sec/SPII): 0.000274
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_001847037 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVIATYLSFSHEFQTRELIEQALKDGKKVLMPKTYPKGRMDFVVYDPQQLVKTSFALLEPQGDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDFIPENHDIPVQEVLIDEGNL
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1921 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.