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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 05-OCT-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_00066 [new locus tag: MDRSPN_RS00355 ]
  • pan locus tag?: PNEUPAN000695000
  • symbol: MDRSPN_00066
  • pan gene symbol?: catE
  • synonym:
  • product: glyoxalase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_00066 [new locus tag: MDRSPN_RS00355 ]
  • symbol: MDRSPN_00066
  • product: glyoxalase
  • replicon: chromosome
  • strand: +
  • coordinates: 71075..71929
  • length: 855
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AP018391 (71075..71929) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0072 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGACCTATGAATACAAGAGTCACATTTATTTGGCAGAGACAGTTTTAAATGTAAAGGAT
    TTGGCCAGTCAAACAGCCTTTTATCAGCAAGTTATTGGTTTAGAAATCTTATCTCAAACT
    GAGACAGAGTCCATTCTAGGCCTTGGTGGAAAAGTCTTGGTACAGCTGATTCAAGCACAA
    GAGAGCGGAGAAGTGAGGGAACATTATGGTCTTTACCATTTGGCCATTCTCTTGCCCACA
    CGCAAGGCTTTAGCTGATGTCTTGAAACACCTGACAGATTTACAAATTCCTCTTGTCGGC
    GGTGCAGACCATGGTTACAGTGAAGCTATTTACTTGGAAGATTTGGAGGGAAATGGCATT
    GAACTCTATCGAGATAAGCCAGTTTCCACATGGGATATTCGAGAAGATGGACGCATTATC
    GGAGTGACAGAGGCTCTTGCGGCGCAGGACATTTATGAGTTGGGGGAAAGAGTAGAGCCC
    TTTATCCTGGCAGAAGGTACGAGAATGGGGCATATTCATCTTTCCGTCAAGGATAGTCGA
    AAGTCCAGCCAGTTTTATCAAAAGGTGTTAGGGCTAGAGGATAAATTCAGTGTGCCTAGC
    GCTAGTTGGATTGCGGCTGGAGATTACCATCATCATTTAGCAGTTAACGAATGGGGAGGA
    AAAGGTCTGGCTTCGCGTAAGCAAGGCTTACCAGGTTTAGCCTACTATGTCATCGAAGTC
    GCACACAAAAAAGAACTGTTAACGATTGCCCAACGAGCACAAGAAGTTGACGCACCAATC
    AAATGGATGACATCGAGCCAATTGGAAATCACAGACTCAGATGGCATCGTGACCCGTATT
    CGTTTAGCAAGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    855

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_00066 [new locus tag: MDRSPN_RS00355 ]
  • symbol: MDRSPN_00066
  • description: glyoxalase
  • length: 284
  • theoretical pI: 5.56039
  • theoretical MW: 31651.8
  • GRAVY: -0.164085

⊟Function[edit | edit source]

  • TIGRFAM:
    3,4-dihydroxyphenylacetate 2,3-dioxygenase (TIGR02295; EC 1.13.11.15; HMM-score: 45.7)
    and 6 more
    Metabolism Energy metabolism Other lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 36.5)
    Metabolism Central intermediary metabolism Amino sugars lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 36.5)
    Metabolism Energy metabolism Other catechol 2,3 dioxygenase (TIGR03211; EC 1.13.11.2; HMM-score: 30.2)
    Metabolism Energy metabolism Other 2,3-dihydroxybiphenyl 1,2-dioxygenase (TIGR03213; EC 1.13.11.39; HMM-score: 26.6)
    lactoylglutathione lyase family protein (TIGR03645; HMM-score: 17.4)
    methylmalonyl-CoA epimerase (TIGR03081; EC 5.1.99.1; HMM-score: 16.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Glyoxalase (CL0104) Glyoxalase; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (PF00903; HMM-score: 65.8)
    and 4 more
    Glyoxalase_6; Glyoxalase-like domain (PF18029; HMM-score: 17.6)
    CppA_C; CppA C-terminal (PF14507; HMM-score: 13.7)
    Glyoxalase_2; Glyoxalase-like domain (PF12681; HMM-score: 12.3)
    no clan defined Imm32; Immunity protein 32 (PF15566; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9985
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0009
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004291
    • TAT(Tat/SPI): 0.000434
    • LIPO(Sec/SPII): 0.000454
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBA58272 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETESILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGADHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEPFILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEWGGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGIVTRIRLAR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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