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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS02285 [old locus tag: MDRSPN_00425 ]
  • pan locus tag?: PNEUPAN001360000
  • symbol: MDRSPN_RS02285
  • pan gene symbol?: nptA
  • synonym:
  • product: Na/Pi cotransporter family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS02285 [old locus tag: MDRSPN_00425 ]
  • symbol: MDRSPN_RS02285
  • product: Na/Pi cotransporter family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 425392..427023
  • length: 1632
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (425392..427023) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0443 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGTCCATTAATTGGCAGGAAATTTTATTTCACTTTTTAGGTGGTCTGGGGCTATTCTTA
    TATAGCATCAAGACCATGGGAGACGGTTTACAACAAGCTGCTGGAGATCGCCTTCGTTTT
    TACATTGACAAATATACTAGTAATCCTTTCTTTGGAGTTCTGGTTGGTATTGGGATGACT
    GCTCTAATTCAGTCTAGTTCTGGTGTAACAGTTATTACAGTCGGCCTGGTCAGTGCCGGT
    CTCTTAACCTTACGTCAGGCTATCGGGATTGTCATGGGTGCTAATATTGGGACAACTGTC
    ACATCCTTTCTCATCGGTTTTAAATTAGGTAACTATGCCCTACCTATGCTCTTTATCGGT
    GCCGTCTGTCTCTTTTTTACAAAAAATCGGACAGTCAATAATATCGGACGCATCCTCTTT
    GGTATCGGTGGTATCTTTTTTGCCCTCAATCTCATGAGCGGCGCAATGGCTCCACTCAAG
    GATTTACAGGTCTTTAAGGACTATATGATTGAGCTAAGTAAGAATCCTGTTTTGGGTGTC
    TTTGTCGGTACTGGCTTGACCTTGCTAATTCAAGCTTCTTCGGCTACCATTGGGATTTTA
    CAAAACCTCTACGCCGGCAATCTAATTGACCTACAGGGAGCTTTGCCAGTTCTATTTGGT
    GACAATATCGGGACAACCATTACAGCCATCATTGCCTCTTTAGGGGCTAATATTGCAGCT
    AAACGGGTAGCAGGAGCTCATGTTGCCTTCAACGTTATCGGAACAGTCGTCTGCGTTATT
    TTTCTAGTTCCTTTTACTGTCCTGATTCATTGGTTTGAAGCTACGCTAAATCTAGCACCG
    GAAATGACCATCGCCTTTGCTCACGGAACCTTTAATATTACCAACACCATTGTCCAATTT
    CCATTTATCGGAGCTCTGGCTTACTTTGTAACCAAGATTATTCCTGGAGAGGACGAGGTT
    GTCAAATACGAACCCTTATATCTTGATGAACATTTCATCAAACAGGCCCCATCTATCGCT
    CTAGGAAATGCTAAGAAAGAGCTCTTGCACTTAGGAAACTACGCTGCTAAAGCCTTTGAC
    CTTTCCTATAAGTACATCATTGGCTTGGATGAAAAAGTTGCTGAAAAAGGGCATAAAACC
    GAAGAAGCAATTAACACCATCGATGAGCAATTAACACGTTATCTCATTGCCCTTTCAAGC
    GAAGCTCTCAGCCAAAAAGAAAGTGAAGTGCTTACCAATATCCTTGATTCCTCCCGTGAT
    TTGGAACGGATTGGAGACCACACGGAGGCTCTACTCAATCTGACTGACTATCTTCAACGG
    AAAAATGTTGAATTTTCTGATGCCGCCTTGAAAGAATTAGAGGAAGTTTACCGCCAAACT
    AGTGACTTTATCAAAGATGCTCTGGATAGTGTGGAAAACAATGATATTGAAAAAGCACGC
    AGTCTTGTAGAACGTCATGAAGCAATCAATAAGATAGAACGTGTTCTCAGAAAAACCCAC
    ATCAAACGCCTCAACAAAGGCGAATGTTCAACACAAGCTGGGGTCAACTTTATCGACATC
    ATCTCACACTACACTCGTGTATCAGACCACGCTATGAACCTTGCTGAAAAGGTTTTTGCA
    GAACAAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1632

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS02285 [old locus tag: MDRSPN_00425 ]
  • symbol: MDRSPN_RS02285
  • description: Na/Pi cotransporter family protein
  • length: 543
  • theoretical pI: 6.10297
  • theoretical MW: 59530.6
  • GRAVY: 0.313444

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds Na/Pi-cotransporter II-related protein (TIGR00704; HMM-score: 232.9)
    and 3 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds sodium-dependent inorganic phosphate (Pi) transporter (TIGR01013; HMM-score: 113.4)
    Metabolism Transport and binding proteins Anions phosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 70.7)
    Signal transduction Regulatory functions Other phosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 70.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Na_Pi_cotrans; Na+/Pi-cotransporter (PF02690; HMM-score: 209.1)
    and 2 more
    PhoU (CL0297) PhoU; PhoU domain (PF01895; HMM-score: 78.3)
    P-loop_NTPase (CL0023) AAA_30; AAA domain (PF13604; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0009
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.082303
    • TAT(Tat/SPI): 0.006046
    • LIPO(Sec/SPII): 0.010017
  • predicted transmembrane helices (TMHMM): 7

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000026631 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDKYTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTSFLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLKDLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVLFGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATLNLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIKQAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIGLDEKVAEKGHKTEEAINTIDEQLTRYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAALKELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGECSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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