From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS04570 [old locus tag: MDRSPN_00866 ]
  • pan locus tag?: PNEUPAN002030000
  • symbol: srtG1
  • pan gene symbol?: srtG1
  • synonym:
  • product: PI-2 pilus system class B sortase SrtG1

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS04570 [old locus tag: MDRSPN_00866 ]
  • symbol: srtG1
  • product: PI-2 pilus system class B sortase SrtG1
  • replicon: chromosome
  • strand: +
  • coordinates: 880124..881122
  • length: 999
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (880124..881122) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAACCAAGCGTGAGAAACCAAAAAAGAGTCTGTCTAGGCGTCTCGTTCTTGCTGTG
    GATGGGGTGATCAATCACTTGCTGCTCATTTTTGCAGCTTTGATCTTTCTCTTTGGTTTC
    TACGCCCTTTGGGATTCCAACCAAGTCTACTCCTTAGCTTCGTCAAGTGAGTACGAAGCT
    TATCGACCTGTCACGACGCAACAGGATGAGCTGGCCAGTTTTTCAGGCTTCAGCAAACTC
    CAAGAACTCAATCCCGAAGTCCTCGGTTGGATCAATGTCTACGGCACCAATATCGACTAT
    CCCTTAGTCCAAGCCAAGGACAATGAAAAGTATCTCAACAAGGACTCCAAAGGTGAGTTT
    GCAGCGACAGGCGCTATCTTTCTCGATGCACGAAATAATCCTAAGTTCGAAGACTTTAAT
    ACCATTATCTACGGGCACCACGTAGAAAATGGGGTCATGTTTGGTGATGTGGCTAAGTTT
    GCTGATCAGGAATTTTTTGACCAGCATCGTTACGGTAGTATATACTACAATGGTGTGGAA
    AAAGGGCTCGAGATCTTTGAGATGTTGGAGGTTGATGCCTATGACTTTAACATCTATGAT
    CCAGGAATACAGGGTGAGGACCGCCAGCAGGCCTATCTAGACCACCTGCTCTCAGTCGCC
    ATGCACAAGCGGGATATCTCACTCTCACCGAGTGATCGTATCATCCTACTCAGTACCTGT
    TTTCTCGATGTGACCAATGGTCGTCATATCGTAGTCGCAAAGATTACAGACACTGTCCCT
    AAAAATACTTTCCATACAAAAAAATCAAAACCATTTCCATACAGTGTCTTTGATGACTCG
    TCTCTTGGACGTTTCCTCTCATCAATCCCACTATGGATTTGGTACCTTATCTTGTTTGTA
    TTGTTCTTGCTCTTGATTTTCTTACTCCTTGTCCTCTACTTGATCCTACGTCGTAGAAGA
    GAGAGTAAAAAAAATGCAAGAAGCAGACCCTTTTACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    999

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS04570 [old locus tag: MDRSPN_00866 ]
  • symbol: SrtG1
  • description: PI-2 pilus system class B sortase SrtG1
  • length: 332
  • theoretical pI: 7.28894
  • theoretical MW: 38371.7
  • GRAVY: -0.107229

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other sortase, SrtB family (TIGR03064; EC 3.4.22.71; HMM-score: 200.8)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking sortase, SrtB family (TIGR03064; EC 3.4.22.71; HMM-score: 200.8)
    and 2 more
    variant surface antigen, rifin family (TIGR01477; HMM-score: 11.5)
    variant surface antigen, stevor family (TIGR01478; HMM-score: 10.1)
  • TheSEED:
  • PFAM:
    no clan defined Sortase; Sortase domain (PF04203; HMM-score: 57.3)
    and 16 more
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 23.4)
    DctQ; Tripartite ATP-independent periplasmic transporters, DctQ component (PF04290; HMM-score: 18.1)
    Orf78; Orf78 (ac78) (PF06024; HMM-score: 15.2)
    DUF4381; Domain of unknown function (DUF4381) (PF14316; HMM-score: 15.2)
    TMEM251; Transmembrane protein 251 (PF15190; HMM-score: 14.8)
    DUF2417; Region of unknown function (DUF2417) (PF10329; HMM-score: 14.5)
    Phage_holin_3_6; Putative Actinobacterial Holin-X, holin superfamily III (PF07332; HMM-score: 13.6)
    SieB; Super-infection exclusion protein B (PF14163; HMM-score: 13)
    Tetraspannin (CL0347) Tetraspanin; Tetraspanin family (PF00335; HMM-score: 10.4)
    no clan defined FixQ; Cbb3-type cytochrome oxidase component FixQ (PF05545; HMM-score: 10.4)
    UstYa; Mycotoxin biosynthesis protein UstYa (PF11807; HMM-score: 10.1)
    VSA (CL0656) RIFIN; Rifin (PF02009; HMM-score: 9.9)
    no clan defined DUF4131; Domain of unknown function (DUF4131) (PF13567; HMM-score: 9.9)
    LapA_dom; Lipopolysaccharide assembly protein A domain (PF06305; HMM-score: 9.6)
    VSA (CL0656) Stevor; Subtelomeric Variable Open Reading frame (PF17410; HMM-score: 8.5)
    no clan defined Pox_EPC_I2-L1; Poxvirus entry protein complex L1 and I2 (PF12575; HMM-score: 8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 2
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9932
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0068
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017809
    • TAT(Tat/SPI): 0.001272
    • LIPO(Sec/SPII): 0.003017
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000851047 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALWDSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPLVQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKFADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLSVAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSVFDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=MDRSPN_RS04570&oldid=106248"