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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-AUG-2015

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_0214 [new locus tag: MYY_RS01115 ]
  • pan locus tag?: PNEUPAN000806000
  • symbol: MYY_0214
  • pan gene symbol?:
  • synonym:
  • product: transposase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: MYY_0214 [new locus tag: MYY_RS01115 ]
  • symbol: MYY_0214
  • product: transposase
  • replicon: chromosome
  • strand: -
  • coordinates: 196363..197292
  • length: 930
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP003357 (196363..197292) NCBI
  • BioCyc: see MYY_RS01115
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGAACAACTTAAGAATACCACAGATTTGCTCGGATTGGAAGACAAAAATATCAAAATC
    TTGTCTGTTCTGAAATACCAAACCCATCTAGTCGTTCAGGCAAAGTTGGATTCCCCCGCT
    CCTCCTTGTCCTCATTGTCAAGGGAAGATGATCAAATACGACTTCCAGAAAGCCTCTAAA
    ATTCCGCTTCTCGACTGTCAGGGTTTACCCACGGTACTGCATCTCAAAAAGCGCCGCTTT
    CAGTGCAAGAATTGCCTTAAGGTGGTCGTTTCTCAAACATCCATTGTCAAGAAAAATTGC
    CAGATTTCCAACATGGTGAGACAAAAAATCGCTCAGCTCCTCCTTGAAAAGCAGTCTATG
    ACTGAGATTGCCCACAGATTGGCGGTCTCAACTTCCACCGTCATCCGAAAACTGAGGGAA
    TTTAAGTTTGAAACCGATTGGACCAAGTTGCCAAAAGTTATGAGTTGGGATGAGTATAGC
    TTCAAAAAAAGCAAAATGAGCTTCATTGCCCAAGATTTTGAGTCCAAATCCATCCTCGCA
    ATTTTAGACGGGCGAACTCATGCGGTGATTCGAAACCATTTCCAACGCTATCAGAGAGAG
    GTTCGGGAGCTGGTCGAGGTCATCACCATGGACATGTACAGCCCTTATTATCGGCTCGCT
    AAGCAACTCTTTCCAAAGGCGAAGATTGTTCTTGACCGCTTCCACATTGTCCAACATCTG
    AGCCGAGCTATGAACCGAGTACGAATCCAAATCATGAACCAATTTGACCGAAAATCCTTG
    GAGTATCGGGCGCTCAAGCGCTTTTGGAACCCTCGCTTTTTCGTTTCTAGGCTCGGGCTA
    AATCAGTCCACTGGACTGATTTACTACACCAGTATAGCTTCAAGCTCTGTCAGAAACGAT
    TCTATCAGCCCACGTTTCGAATGCACTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    930

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: MYY_0214 [new locus tag: MYY_RS01115 ]
  • symbol: MYY_0214
  • description: transposase
  • length: 309
  • theoretical pI: 10.5801
  • theoretical MW: 36242.4
  • GRAVY: -0.338511

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Sporulation and germination RNA polymerase sigma-H factor (TIGR02859; HMM-score: 13.1)
    Genetic information processing Transcription Transcription factors RNA polymerase sigma-H factor (TIGR02859; HMM-score: 13.1)
    Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 12.7)
    RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 12.6)
    Signal transduction Regulatory functions DNA interactions TyrR family helix-turn-helix domain (TIGR04381; HMM-score: 12.2)
  • TheSEED  :
    • Degenerate transposase (orf2)
  • PFAM:
    RNase_H (CL0219) DDE_Tnp_ISL3; Transposase (PF01610; HMM-score: 95.2)
    and 24 more
    HTH (CL0123) HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 44.4)
    Zn_Beta_Ribbon (CL0167) zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 42.1)
    HTH (CL0123) HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 24.1)
    HTH_50; Helix-turn-helix domain (PF18024; HMM-score: 24.1)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 20.9)
    no clan defined TnsD; Tn7-like transposition protein D (PF15978; HMM-score: 18.4)
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 18.2)
    Zn_Beta_Ribbon (CL0167) Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 15.8)
    HTH (CL0123) Trp_repressor; Trp repressor protein (PF01371; HMM-score: 15.7)
    HTH_AsnC-type; AsnC-type helix-turn-helix domain (PF13404; HMM-score: 15.6)
    HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 14.8)
    HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 14.7)
    HTH_32; Homeodomain-like domain (PF13565; HMM-score: 14.4)
    HTH_29; Winged helix-turn helix (PF13551; HMM-score: 14.3)
    Mga; Mga helix-turn-helix domain (PF05043; HMM-score: 13.9)
    HTH_40; Helix-turn-helix domain (PF14493; HMM-score: 13.8)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 13.5)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 13.4)
    Peroxisome (CL0484) Reticulon; Reticulon (PF02453; HMM-score: 13.1)
    Zn_Beta_Ribbon (CL0167) Ogr_Delta; Ogr/Delta-like zinc finger (PF04606; HMM-score: 13.1)
    Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 13)
    CDA (CL0109) Pput2613-deam; Pput_2613-like deaminase (PF14427; HMM-score: 12.7)
    HTH (CL0123) HTH_6; Helix-turn-helix domain, rpiR family (PF01418; HMM-score: 11)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7631
    • Cytoplasmic Membrane Score: 0.0293
    • Cell wall & surface Score: 0.0393
    • Extracellular Score: 0.1683
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.031166
    • TAT(Tat/SPI): 0.002253
    • LIPO(Sec/SPII): 0.00202
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFC93876 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MEQLKNTTDLLGLEDKNIKILSVLKYQTHLVVQAKLDSPAPPCPHCQGKMIKYDFQKASKIPLLDCQGLPTVLHLKKRRFQCKNCLKVVVSQTSIVKKNCQISNMVRQKIAQLLLEKQSMTEIAHRLAVSTSTVIRKLREFKFETDWTKLPKVMSWDEYSFKKSKMSFIAQDFESKSILAILDGRTHAVIRNHFQRYQREVRELVEVITMDMYSPYYRLAKQLFPKAKIVLDRFHIVQHLSRAMNRVRIQIMNQFDRKSLEYRALKRFWNPRFFVSRLGLNQSTGLIYYTSIASSSVRNDSISPRFECT

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]