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serotype 1

NCBI: 03-AUG-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_1933 [new locus tag: MYY_RS10140 ]
  • pan locus tag?: PNEUPAN003645000
  • symbol: MYY_1933
  • pan gene symbol?: rluD2
  • synonym:
  • product: pseudouridine synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MYY_1933 [new locus tag: MYY_RS10140 ]
  • symbol: MYY_1933
  • product: pseudouridine synthase
  • replicon: chromosome
  • strand: +
  • coordinates: 1908656..1909492
  • length: 837
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGACGGTAAAGCAATTACTTGAGGAACAACTCCTCATCCCTAGAAAAATCCGTCATTTT
    TTGAGAATCAAGAAACATATTTTGATAAATCAAGAAGAAGTCCACTGGAACGAAATCGTA
    AATCCTGGAGATGTTTGCCAGTTGACTTTTGACGAGGAAGATTATTCCCAAAAGACGATC
    CCTTGGGGCAACCCAGACTTAGTGCAGGAAGTTTATCAAGATCAACACTTGATTATTGTA
    AACAAACCAGAGGGGATGAAAACGCATGGTAATCAACCAAACGAAATTGCCCTTCTTAAC
    CATGTCAGTACCTATGTTGGCCAAACCTGCTATGTCGTTCATCGTCTGGACATGGAAACC
    AGTGGCTTAGTTCTCTTTGCCAAAAATCCTTTTATCCTGCCCATTCTCAATCGCTTATTG
    GAGAAAAAAGAGATTTCTAGAGAATATTGGGCTCTAGTTGATGGAAATATCAACAGAAAA
    GAACTTGTTTTCAGAGACAAAATTGGACGTGATCGCCATGATCGTAGAAAAAGAATAGTT
    GATGCAAAAAATGGGCAATATGCTGAAACGTATGTAAGCAGATTAAAGCAATTCTCAAAC
    AAGACTTCCTTGGCTCATTGCAAGCTAAAGACAGGGCGAACCCATCAGATTCGTGTGCAC
    CTTTCGCATCATAACTTCCCTATTTTGGGCGACCCTCTCTATAACAGCAATTCAAAGACA
    AGTCGGCTTATGCTTCATGCCTTTCGACTTTCCTTTACCCATCCACTTACATTAGAAAAA
    TTAAACTTCACTGCCCTCTCAAATACTTTTGAAACAGAATTAAAAAAGAATGGATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    837

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MYY_1933 [new locus tag: MYY_RS10140 ]
  • symbol: MYY_1933
  • description: pseudouridine synthase
  • length: 278
  • theoretical pI: 9.85523
  • theoretical MW: 32547.2
  • GRAVY: -0.556475

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 190.7)
    and 2 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 100.3)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase (TIGR00093; EC 5.4.99.-; HMM-score: 33.1)
  • TheSEED  :
    • Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YhcT type
    Protein Metabolism Protein biosynthesis Ribosome biogenesis bacterial  Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YhcT type
  • PFAM:
    PseudoU_synth (CL0649) PseudoU_synth_2; RNA pseudouridylate synthase (PF00849; HMM-score: 116.9)
    and 1 more
    PA14 (CL0301) PA14; PA14 domain (PF07691; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.944
    • Cytoplasmic Membrane Score: 0.0526
    • Cell wall & surface Score: 0.0014
    • Extracellular Score: 0.002
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001565
    • TAT(Tat/SPI): 0.0001
    • LIPO(Sec/SPII): 0.000201
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFC95588 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLAHCKLKTGRTHQIRVHLSHHNFPILGDPLYNSNSKTSRLMLHAFRLSFTHPLTLEKLNFTALSNTFETELKKNG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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