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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-NOV-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_RS10400 [old locus tag: MYY_1984 ]
  • pan locus tag?: PNEUPAN003799000
  • symbol: MYY_RS10400
  • pan gene symbol?: MATE
  • synonym:
  • product: MATE family efflux transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MYY_RS10400 [old locus tag: MYY_1984 ]
  • symbol: MYY_RS10400
  • product: MATE family efflux transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 1956192..1957472
  • length: 1281
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017769 (1956192..1957472) NCBI
  • BioCyc: MYY_RS10400 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1876 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    TTGTTTAAGAAAAATAAAGACATTCTTAATATTGCATTGCCAGCTATGGGTGAAAACTTT
    TTGCAGATGCTAATGGGAATGGTGGACAGTTATTTGGTTGCTCATTTAGGATTGATAGCT
    ATTTCAGGGGTTTCAGTAGCTGGTAATATTATCACCATTTATCAGGCGATTTTCATCGCT
    CTGGGAGCTGCTATTTCCAGTGTTATTTCAAAAAGCATAGGGCAGAAAGACCAGTCGAAG
    TTGGCCTATCATGTGACTGAGGCGTTGAAGATTACCTTACTATTAAGTTTCCTTTTAGGA
    TTTTTGTCCATCTTCGCTGGGAAAGAGATGATAGGACTTTTGGGGACGGAGAGGGATGTA
    GCTGAGAGTGGTGGACTGTATCTATCTTTGGTAGGCGGATCGATTGTTCTCTTAGGTTTA
    ATGACTAGTCTGGGAGCCTTGATTCGTGCAACGCATAATCCACGTTTGCCTCTCTATGTT
    AGTTTTTTATCCAATGCCTTGAATATTCTTTTTTCAAGTCTAGCTATTTTTGTTCTGGAT
    ATGGGGATAGCTGGTGTTGCTTGGGGGACAATTCTGTCTCGTTTGGTTGGTCTTGTGATT
    TTGTGGTCACAATTAAAACTGCCTTATGGGAAGCCAACTTTTGGTTTAGATAAGGAACTG
    TTGACCTTGGCTTTACCAGCAGCTGGAGAGCGACTTATGATGAGGGCTGGAGATGTAGTG
    ATCATTGCCTTGGTCGTTTCTTTTGGGACGGAGGCAGTTGCTGGGAATGCAATCGGAGAA
    GTCTTGACCCAGTTTAACTATATGCCTGCCTTTGGCGTCGCTACGGCAACGGTCATGCTG
    TTGGCCCGAGCAGTTGGAGAGGATGATTGGAAAAGAGTCGCTAGTTTGAGTAAACAAACC
    TTTTGGCTTTCTCTGTTCCTCATGTTGCCCCTGTACTTTAGTATATATGTCTTGGGTGTA
    CCATTAACTCATCTCTATACGACTGATTCTCTAGCGGTGGAGGCTAGTGTTCTAGTGACA
    CTGTTTTCACTACTTGGAACCCCTATGACGACAGGAACAGTCATCTATACGGCAGTCTGG
    CAGGGATTAGGAAATGCACGCCTCCCTTTTTATGCGACAAGTATAGGCATGTGGTGTATC
    CGCATTGGAACAGGATATCTGCTGGGGATTGTGCTTGGTTGGGGCTTGCCTGGTATTTGG
    GCAGGGTCTCTCTTGGATAATGGTTTTCGCTGGTTATTTCTACGCTATCGTTACCAGCGC
    TATATGAGCTTGAAAGGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1281

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MYY_RS10400 [old locus tag: MYY_1984 ]
  • symbol: MYY_RS10400
  • description: MATE family efflux transporter
  • length: 426
  • theoretical pI: 9.53884
  • theoretical MW: 45973.4
  • GRAVY: 0.781455

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other MATE efflux family protein (TIGR00797; HMM-score: 200.8)
    and 1 more
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan murein biosynthesis integral membrane protein MurJ (TIGR01695; HMM-score: 47.2)
  • TheSEED: see MYY_1984
  • PFAM:
    MviN_MATE (CL0222) MatE; MatE (PF01554; HMM-score: 160.5)
    and 2 more
    MurJ; Lipid II flippase MurJ (PF03023; HMM-score: 51.8)
    Polysacc_synt_C; Polysaccharide biosynthesis C-terminal domain (PF14667; HMM-score: 28.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017493
    • TAT(Tat/SPI): 0.000198
    • LIPO(Sec/SPII): 0.002561
  • predicted transmembrane helices (TMHMM): 11

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000473961 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGVSVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFLSIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYVSFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDKELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATATVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLYFSIYVLGVPLTHLYTTDSLAVEASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVLGWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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