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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JUN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7466
  • locus tag: NCTC7466_00486 [new locus tag: DQM66_RS11865 ]
  • pan locus tag?: PNEUPAN001401000
  • symbol: blpA2
  • pan gene symbol?: blpA2
  • synonym:
  • product: bacteriocin transporter C39 protease domain BlpA2

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NCTC7466_00486 [new locus tag: DQM66_RS11865 ]
  • symbol: blpA2
  • product: bacteriocin transporter C39 protease domain BlpA2
  • replicon: chromosome
  • strand: -
  • coordinates: 483036..483623
  • length: 588
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: LS483374 (483036..483623) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCT
    GCCTTAGCCTCGATTGCTAAATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAA
    CTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCATTGTAAAAGCCGCTGATGAA
    ATGGGCTTTGAAACAAGACCTGTTCAAGCATATAAAACGCTCTTTGACATGAGTGATGTC
    CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAATTCCAACATTACTATGTTGTC
    TATCAAACAAAGAAAGACTATCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACT
    AAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAGTAGCTATTTTTCTAGCTACC
    AAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
    TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCAC
    TATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    588

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NCTC7466_00486 [new locus tag: DQM66_RS11865 ]
  • symbol: BlpA2
  • description: bacteriocin transporter C39 protease domain BlpA2
  • length: 195
  • theoretical pI: 9.70725
  • theoretical MW: 22352.7
  • GRAVY: -0.329231

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.22.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 200.8)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 200.8)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 200.8)
    and 5 more
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 70.5)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 70.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 22)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 11.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 11.3)
  • TheSEED:
  • PFAM:
    Peptidase_CA (CL0125) Peptidase_C39; Peptidase C39 family (PF03412; HMM-score: 137.7)
    and 2 more
    Peptidase_C70; Papain-like cysteine protease AvrRpt2 (PF12385; HMM-score: 21.4)
    Peptidase_C39_2; Peptidase_C39 like family (PF13529; HMM-score: 18)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 9.99
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.2062
    • Cytoplasmic Membrane Score: 0.5984
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.1946
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010344
    • TAT(Tat/SPI): 0.003585
    • LIPO(Sec/SPII): 0.001808
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: SQG01539 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQAYKTLFDMSDVPYPFIVHVNKEGKFQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSSDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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