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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JUN-2018

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7466
  • locus tag: NCTC7466_00749 [new locus tag: DQM66_RS03900 ]
  • pan locus tag?: PNEUPAN001798000
  • symbol: NCTC7466_00749
  • pan gene symbol?:
  • synonym:
  • product: phosphopentomutase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NCTC7466_00749 [new locus tag: DQM66_RS03900 ]
  • symbol: NCTC7466_00749
  • product: phosphopentomutase
  • replicon: chromosome
  • strand: +
  • coordinates: 740475..740885
  • length: 411
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: LS483374 (740475..740885) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0725 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGACGCGCTATGCTTTGCTGGTGAGAGGTATCAATGTTGGTGGTAAGAATAAGGTCGTC
    ATGGCGGAACTTCGTCAAGAATTGACAAACTTGGGACTGGAAAAGGTTGAGAGCTACATC
    AACAGTGGCAATATTTTCTTTACTTCGATAGATTCCAAAGCCCAATTGGTTGAAAAGCTA
    GAGACTTTCTTTGCAGTCCATTATCCATTTATTCAGAGCTTTTCTTTACTGAGTCTAGAG
    GACTTTGAGGCGGAACTTGAAAATCTACCAGCTTGGTGGAGCAGAGACTTGGCACGAAAA
    GATTTTCTCTTTTACACTGAGGGTTTGGATGTGGACCAAGTCATCGCGACAGTTGAAAGT
    TTAGAGCTGAAAGATGAAGTGCTTTATTTTGGAAAACTTGGGATTTTCTAG
    60
    120
    180
    240
    300
    360
    411

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NCTC7466_00749 [new locus tag: DQM66_RS03900 ]
  • symbol: NCTC7466_00749
  • description: phosphopentomutase
  • length: 136
  • theoretical pI: 4.35146
  • theoretical MW: 15596.7
  • GRAVY: 0.0823529

Function[edit | edit source]

  • reaction:
    EC 5.4.2.7?  ExPASy
    Phosphopentomutase Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate
  • TIGRFAM:
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    no clan defined DUF1697; Protein of unknown function (DUF1697) (PF08002; HMM-score: 105.4)
    and 2 more
    HeH (CL0306) SAP; SAP domain (PF02037; HMM-score: 14.5)
    NADP_Rossmann (CL0063) Shikimate_DH; Shikimate / quinate 5-dehydrogenase (PF01488; HMM-score: 12)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005609
    • TAT(Tat/SPI): 0.000238
    • LIPO(Sec/SPII): 0.000623
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: SQG01797 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGNIFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDFLFYTEGLDVDQVIATVESLELKDEVLYFGKLGIF

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]