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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BM6001
  • locus tag: ODS73_01770 [new locus tag: ODS73_RS01770 ]
  • pan locus tag?: PNEUPAN001001000
  • symbol: glmS
  • pan gene symbol?: glmS
  • synonym:
  • product: glutamine--fructose-6-phosphate transaminase (isomerizing)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ODS73_01770 [new locus tag: ODS73_RS01770 ]
  • symbol: glmS
  • product: glutamine--fructose-6-phosphate transaminase (isomerizing)
  • replicon: chromosome
  • strand: +
  • coordinates: 306470..308278
  • length: 1809
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: CP107038 (306470..308278) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0248 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTGTGGAATTGTTGGTGTTGTTGGAAACACAAATGCAACTGATATTTTGATTCAAGGG
    CTTGAAAAGCTTGAATACCGTGGCTATGATTCTGCGGGAATTTTTGTCCTAGATGGTGCT
    GATAACCATTTGGTGAAGGCGGTTGGTCGTATTGCAGAATTGTCTGCCAAGACAGCTGGT
    GTTGAGGGAACAACTGGTATCGGACATACTCGTTGGGCTACTCACGGAAAACCAACTGAG
    GACAATGCTCACCCACACCGCTCTGAGACAGAACGTTTTGTCTTGGTGCATAATGGGGTG
    ATTGAGAACTATCTTGAAATCAAGGAAGAATACCTTGCAGGTCACCACTTCAAGGGGCAG
    ACAGATACTGAAATAGCCGTTCATTTGATTGGAAAATTTGCGGAAGAAGAAGGGCTCTCA
    GTTCTTGAAGCCTTCAAAAAAGCCCTTCACATCATCCGTGGTTCTTATGCCTTTGCCTTG
    GTTGACTCACAAGATCCTGAAGTCATCTACGTAGCTAAAAATAAATCACCACTTTTGATT
    GGTCTTGGAGAAGGCTATAACATGGTCTGCTCAGACGCCATGGCTATGATTCGTGAAACT
    AACCAATACATGGAAATCCATGACCAAGAGTTGGTAATCGTCAAGGCTGATAGTGTGGAA
    GTTCAAGACTATGATGGAAATCGTCGTGAGCGTGCTAGCTACACTGCTGAACTTGACTTG
    TCAGATATCGGTAAGGGAACTTACCCTTACTACATGCTCAAGGAAATTGACGAGCAACCA
    ACTGTTATGCGTAAACTCATTCAAGCCTACACGGATGATGCTGGTCAAGTAGTGGTTGAT
    CCTGCTATCATTAAGGCTGTTCAAGACGCAGACCGCATCTACATCCTTGCAGCTGGAACA
    TCTTACCATGCAGGATTTGCTTCTAAGAAAATGTTGGAAGAATTGACAGATACACCAGTT
    GAACTTGGCATCTCATCTGAGTGGGGCTACGGTATGCCACTTCTCAGCAAGAAACCACTC
    TTCATCTTTATCAGCCAATCTGGTGAAACAGCGGATAGTCGTCAAGTTTTGGTCAAGGCT
    AATGAAATGGGAATTCCAAGCTTAACAGTGACAAATGTTCCAGGCTCAACCCTCTCACGT
    GAAGCCAACTATACCATGCTCCTTCACGCAGGTCCTGAAATTGCCGTGGCATCAACTAAA
    GCCTATACAGCGCAAATCGCAGCCCTTGCCTTCCTTGCAAAAGCAGTCGGAGAAGCAAAT
    GGTAATGCTAAAGCGCAAGCCTTTGACCTGATTCATGAATTGTCAATCGTAGCTCAGTCT
    ATCGAATCAACTCTTTCAGAGAAAGAAACCATTGAAGCCAAGGTTCGTGAACTTCTTGAA
    ACAACTCGTAACGCCTTTTACATCGGACGTGGTCAAGATTACTACGTAGCCATGGAAGCA
    AGTCTCAAACTCAAAGAGATTTCTTATATCCAGTGTGAAGGCTTTGCTGCAGGAGAACTC
    AAGCACGGAACCATTGCCTTGATTGAAGAAGGAACGCCTGTTTTGGCTCTCTTGTCAGAT
    CCAGTTCTTGCCAATCATACTCGTGGAAATATCCAAGAGGTCGCAGCCCGTGGTGCCAAA
    GTCCTCACTATCGCAGAAGAGAATGTAGCCAAAGATACCGACGATATCGTCCTTACGACC
    GTACATCCATACCTCTCACCAATTTCAATGGTCGTACCAACGCAATTAGTCGCTTACTTT
    GCAACCCTCCACCGTGGCCTCGATGTGGATAAACCACGTAACCTTGCTAAATCAGTAACG
    GTAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1809

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ODS73_01770 [new locus tag: ODS73_RS01770 ]
  • symbol: GlmS
  • description: glutamine--fructose-6-phosphate transaminase (isomerizing)
  • length: 602
  • theoretical pI: 4.83423
  • theoretical MW: 65561
  • GRAVY: -0.0784053

⊟Function[edit | edit source]

  • reaction:
    EC 2.6.1.16?  ExPASy
    Glutamine--fructose-6-phosphate transaminase (isomerizing) L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate
  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan glutamine-fructose-6-phosphate transaminase (isomerizing) (TIGR01135; EC 2.6.1.16; HMM-score: 709)
    Metabolism Central intermediary metabolism Amino sugars glutamine-fructose-6-phosphate transaminase (isomerizing) (TIGR01135; EC 2.6.1.16; HMM-score: 709)
    and 10 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis amidophosphoribosyltransferase (TIGR01134; EC 2.4.2.14; HMM-score: 108.4)
    Metabolism Amino acid biosynthesis Aspartate family asparagine synthase (glutamine-hydrolyzing) (TIGR01536; EC 6.3.5.4; HMM-score: 57.6)
    exosortase A system-associated amidotransferase 1 (TIGR03108; HMM-score: 27.6)
    6-phospho 3-hexuloisomerase (TIGR03127; EC 5.3.-.-; HMM-score: 27.4)
    Metabolism Energy metabolism Sugars sugar isomerase, KpsF/GutQ family (TIGR00393; HMM-score: 23.7)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan N-acetylmuramic acid 6-phosphate etherase (TIGR00274; EC 4.2.1.126; HMM-score: 22.7)
    asparagine synthase family amidotransferase (TIGR03104; HMM-score: 19.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs ergothioneine biosynthesis protein EgtC (TIGR03442; HMM-score: 15.6)
    Hypothetical proteins Conserved TIGR00161 family protein (TIGR00161; HMM-score: 13.5)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other inosine/xanthosine triphosphatase (TIGR00258; HMM-score: 13.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    SIS (CL0067) SIS; SIS domain (PF01380; HMM-score: 160.8)
    and 3 more
    NTN (CL0052) GATase_6; Glutamine amidotransferase domain (PF13522; HMM-score: 79.7)
    GATase_7; Glutamine amidotransferase domain (PF13537; HMM-score: 56.6)
    GATase_4; Glutamine amidotransferases class-II (PF13230; HMM-score: 26.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9844
    • Cytoplasmic Membrane Score: 0.0026
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0124
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007073
    • TAT(Tat/SPI): 0.000317
    • LIPO(Sec/SPII): 0.000994
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WIA46127 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHLVKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIENYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFALVDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADSVEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQVVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPLLSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKETIEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALIEEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLSPISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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