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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BM6001
  • locus tag: ODS73_09980 [new locus tag: ODS73_RS09990 ]
  • pan locus tag?: PNEUPAN003524000
  • symbol: ODS73_09980
  • pan gene symbol?: slyA_2
  • synonym:
  • product: MarR family winged helix-turn-helix transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ODS73_09980 [new locus tag: ODS73_RS09990 ]
  • symbol: ODS73_09980
  • product: MarR family winged helix-turn-helix transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 1915145..1915594
  • length: 450
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP107038 (1915145..1915594) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_2411 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGATAAACCGATGTTAGTCTTTAAGCGTTTTGGTCATCAAATTCACCTGATGGTGCAA
    AAGGAAGCCAAACGTTGCGGCATTGAATTTATGGGTGGGCCGCAAGGTCAGGTTGTGCAT
    TTTTTGGATAATCGCGAGAAAAACCAAGACTTGGTCTTGATTAAAGATATCGAGCAGGAA
    CTCAATATTACCAAGTCTGTTGCTAGTAATCTGGTTAAGCGTATAGTGCAAAATGGTTTG
    GTGGAATTGGAGGCGAGTCCTGTTGATAAGCGGGCTAAGTTTGTTCGTCTGACGGACAAA
    GCACGTTCTCAGATGCAACAGGTTAAGGCTTTTTTTGAACGCATAGACAAGCAGTTGATG
    GAAGACATTGATGAAGATGAATTACTGATTTTTGAGAAGGTTCTCGGTCAACTACAGGCA
    AAATATCAAGGGAATAGGAGGAGAGAATAA
    60
    120
    180
    240
    300
    360
    420
    450

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ODS73_09980 [new locus tag: ODS73_RS09990 ]
  • symbol: ODS73_09980
  • description: MarR family winged helix-turn-helix transcriptional regulator
  • length: 149
  • theoretical pI: 9.60822
  • theoretical MW: 17409.1
  • GRAVY: -0.543624

⊟Function[edit | edit source]

  • TIGRFAM:
    mobile rSAM pair MarR family regulator (TIGR04472; HMM-score: 36.1)
    and 4 more
    homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 23.7)
    Signal transduction Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 19.1)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, Acidobacterial, PadR-family (TIGR03433; HMM-score: 18.5)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaD family protein (TIGR04548; HMM-score: 17.5)
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    HTH (CL0123) MarR_2; MarR family (PF12802; HMM-score: 52.8)
    and 7 more
    HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 37.9)
    MarR; MarR family (PF01047; HMM-score: 24.7)
    Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 20.2)
    HTH_34; Winged helix DNA-binding domain (PF13601; HMM-score: 14.8)
    Rrf2; Iron-dependent Transcriptional regulator (PF02082; HMM-score: 12.9)
    no clan defined Tfb5; Transcription factor TFIIH complex subunit Tfb5 (PF06331; HMM-score: 12.3)
    HTH (CL0123) TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by SlyA_2*, TF important in Multidrug resistance: in TIGR4

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006166
    • TAT(Tat/SPI): 0.000192
    • LIPO(Sec/SPII): 0.001104
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WIA45471 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDNREKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKARSQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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