PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN000794000
• symbol^?: mnmA
• synonym:
• description^?: tRNA 2-thiouridine(34) synthase MnmA

  descriptions from strain specific annotations:

  • tRNA 2-thiouridine(34) synthase MnmA
  • tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
  • tRNA-specific 2-thiouridylase MnmA
  • putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
  • thiouridylase
  • Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
  • tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
• strand^?: +
• coordinates^?: 961544..962665
• occurrence^?: in 100% of 43 strains

⊟Orthologs

TIGR4:
SP_RS00600 (mnmA)
D39:
SPD_RS00700 (mnmA)
D39V:
SPV_RS00700 (mnmA)
Hungary19A-6:
SPH_RS01115 (mnmA)
EF3030:
EF3030_RS00665 (mnmA)
670-6B:
SP670_RS01030 (mnmA)
6A-10:
HKM25_RS00735 (mnmA)
70585:
SP70585_RS00955 (mnmA)
A026:
T308_RS00575 (mnmA)
A66:
A66_RS00680 (mnmA)
AP200:
SPAP_RS00870 (mnmA)
ASP0581:
EL334_RS00705 (mnmA)
ATCC 49619:
EL263_RS00880 (mnmA)
ATCC 700669:
SPN23F_RS00685 (mnmA)
BM6001:
ODS73_RS01040 (mnmA)
BVJ1JL:
JN057_RS00885 (mnmA)
CGSP14:
SPCG_RS00665 (mnmA)
G54:
SPG_RS00635 (mnmA)
gamPNI0373:
HMPREF1038_RS00915 (mnmA)
HU-OH:
EL271_RS00670 (mnmA)
Hu15:
SPNHU15_RS08220 (mnmA)
Hu17:
SPNHU17_RS00850 (mnmA)
INV104:
INV104_RS00605 (mnmA)
INV200:
SPNINV200_RS00650 (mnmA)
JJA:
SPJ_RS00745 (mnmA)
MDRSPN001:
MDRSPN_RS00695 (mnmA)
NCTC7465:
AT689_RS01785 (mnmA)
NCTC7466:
DQM66_RS00700 (mnmA)
NU83127:
EL277_RS00675 (mnmA)
OXC141:
SPNOXC_RS00920 (mnmA)
P1031:
SPP_RS00910 (mnmA)
R6:
SPR_RS00670 (mnmA)
SP49:
BMJ42_RS01215 (mnmA)
SPN032672:
SPN032672_RS06890 (mnmA)
SPN034156:
SPN034156_RS06850 (mnmA)
SPN034183:
SPN034183_RS00925 (mnmA)
SPN994038:
SPN994038_RS00855 (mnmA)
SPN994039:
SPN994039_RS00850 (mnmA)
SPNA45:
SPNA45_RS10645 (mnmA)
ST556:
MYY_RS01050 (mnmA)
Taiwan19F-14:
SPT_RS00840 (mnmA)
TCH8431/19A:
HMPREF0837_RS02115 (mnmA)
Xen35:
CXP32_RS00620 (mnmA)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVV
  D39             MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVV
  D39V            MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVV
  Hungary19A-6    MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVV
  EF3030          MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVV
                  ************************************************************
  
  TIGR4           AVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAITLG
  D39             AVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLG
  D39V            AVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLG
  Hungary19A-6    AVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLG
  EF3030          AVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLG
                  ********************************************************:***
  
  TIGR4           ADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLEKPEVR
  D39             ADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLKKPEVR
  D39V            ADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLKKPEVR
  Hungary19A-6    ADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLEKPEVR
  EF3030          ADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLEKPEVR
                  ******************************************************:*****
  
  TIGR4           RLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQPGRMMTVDGRDMGEHAGLMYYT
  D39             KLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQPGRMMTVDGRDMGEHAGLMYYT
  D39V            KLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQPGRMMTVDGRDMGEHAGLMYYT
  Hungary19A-6    RLAEEAGLATAKKKDSTGICFIGEKNFKNLLSNYLPAQPGRMMTVDGRDMGEHAGLMYYT
  EF3030          KLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQPGRMMTVDGRDMGEHAGLMYYT
                  :*******:********************:******************************
  
  TIGR4           IGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQGFYHDSLMSTSLEASQVHFTREMP
  D39             IGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQGFYHDSLMSTSLEASQVHFTREMP
  D39V            IGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQGFYHDSLMSTSLEASQVHFTREMP
  Hungary19A-6    IGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQGFYHDSLMSTSLEASQVHFTREMP
  EF3030          IGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQGFYHDSLMSTNLEASQVHFTREMP
                  **********************************************.*************
  
  TIGR4           EEFTLECTAKFRYRQPDSKVTVHVKGEKTEVIFAEPQRAITPGQAVVFYDGEECLGGGLI
  D39             EEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFAEPQRAITPGQAVVFYDGEECLGGGLI
  D39V            EEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFAEPQRAITPGQAVVFYDGEECLGGGLI
  Hungary19A-6    EEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFAEPQRAITPGQAVVFYDGEECLGGGLI
  EF3030          EEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFAEPQRAITPGQAVVFYDGEECLGGGLI
                  **************************:*:*******************************
  
  TIGR4           DNAYRDGQVCQYI
  D39             DNAYRDGQVCQYI
  D39V            DNAYRDGQVCQYI
  Hungary19A-6    DNAYRDGQVCQYI
  EF3030          DNAYRDGQVCQYI
                  *************