PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN001561000
• symbol^?: nha2
• synonym:
• description^?: cation:proton antiporter

  descriptions from strain specific annotations:

  • cation:proton antiporter
  • Na+/H+ antiporter
  • putative sodium hydrogen exchange transporter
  • sodium/hydrogen exchanger family protein
  • sodium:hydrogen antiporter
  • Sodium, potassium, lithium and rubidium/H(+)
  • sodium:proton antiporter
  • transporter, monovalent cation:proton antiporter-2 (CPA2) family
  • NhaP-type Na+/H+ and K+/H+ antiporter
  • transporter, CPA2 family
  • pseudogene
• strand^?: +
• coordinates^?: 1984199..1986253
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS03215
(2)
D39:
SPD_RS03075
(2)
D39V:
SPV_RS03070
(19A)
Hungary19A-6:
SPH_RS03645
(19F)
EF3030:
EF3030_RS03085
(6B)^?
670-6B:
SP670_RS03565
(6A)
6A-10:
HKM25_RS03120
(5)
70585:
SP70585_RS03500
(19F)
A026:
T308_RS03125
(3)
A66:
A66_RS02970
(11A)
AP200:
SPAP_RS03190
(12F)
ASP0581:
EL334_RS03285
(19F)
ATCC 49619:
EL263_RS03240
(23F)
ATCC 700669:
SPN23F_RS03025
(19F)
BM6001:
ODS73_RS03510
(1)
BVJ1JL:
JN057_RS03240
(14)
CGSP14:
SPCG_RS03220
(19F)
G54:
SPG_RS03030
(1)
gamPNI0373:
HMPREF1038_RS03350
(3)
HU-OH:
EL271_RS03030
(19A)
Hu15:
SPNHU15_RS03305
(19A)
Hu17:
SPNHU17_RS03240
(1)
INV104:
INV104_RS03220
(14)
INV200:
SPNINV200_RS03090
(14)
JJA:
SPJ_RS03040
(19F)
MDRSPN001:
MDRSPN_RS07350
(1)
NCTC7465:
AT689_RS10450
(2)
NCTC7466:
DQM66_RS03075
(4)
NU83127:
EL277_RS03315
(3)
OXC141:
SPNOXC_RS03220
(1)
P1031:
SPP_RS03300
(2)
R6:
SPR_RS02905
(19A)
SP49:
BMJ42_RS03800
(1)
SPN032672:
SPN032672_RS09480
(3)
SPN034156:
SPN034156_RS09145
(3)
SPN034183:
SPN034183_RS03235
(3)
SPN994038:
SPN994038_RS03155
(3)
SPN994039:
SPN994039_RS03155
(3)
SPNA45:
SPNA45_RS05600
(19F)
ST556:
MYY_RS03605
(19F)
Taiwan19F-14:
SPT_RS03385
(19A)
TCH8431/19A:
HMPREF0837_RS04555
(4)
Xen35:
CXP32_RS03290

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFLPNTDFHLNTELFLALV
  D39             MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFLPNTDFHLNTELFLALV
  D39V            MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFLPNTDFHLNTELFLALV
  EF3030          MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFLPNTDFHLNTELFLALV
                  ************************************************************
  
  TIGR4           IGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGLAHLLWFSLPLAACLAVGA
  D39             IGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGLAHLLWFSLPLAACLAVGA
  D39V            IGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGLAHLLWFSLPLAACLAVGA
  EF3030          IGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGLAHLLWFSLPLAACLAVGA
                  ************************************************************
  
  TIGR4           ALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLVAFQVALTAWTTGAFSLGQAS
  D39             ALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLVAFQVALTAWTTGAFSLGQAS
  D39V            ALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLVAFQVALTAWTTGAFSLGQAS
  EF3030          ALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLVAFQVALTAWTTGAFSLGQAS
                  ************************************************************
  
  TIGR4           SSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIASELLLELSLPLVTFFLAEEVHVS
  D39             SSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIASELLLELSLPLVTFFLAEEVHVS
  D39V            SSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIASELLLELSLPLVTFFLAEEVHVS
  EF3030          SSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIASELLLELSLPLVTFFLAEEVHVS
                  ************************************************************
  
  TIGR4           GIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHTVTFMLNGSVFVILGMELEMIAEPI
  D39             GIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHTVTFMLNGSVFVILGMELEMIAEPI
  D39V            GIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHTVTFMLNGSVFVILGMELEMIAEPI
  EF3030          GIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHTVTFMLNGSVFVILGMELEMIAEPI
                  ************************************************************
  
  TIGR4           LTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYYAYRTRRLKKKLNKYMKDMFLLTFSGV
  D39             LTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYYAYRTRRLKKKLNKYMKDMFLLTFSGV
  D39V            LTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYYAYRTRRLKKKLNKYMKDMFLLTFSGV
  EF3030          LTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYYAYRTRRLKKKLNKYMKDMFLLTFSGV
                  ************************************************************
  
  TIGR4           KGTVSIATILLIPSNLEQEYPLLLFLVAGVTLVSFLTGLLVLPHLSDEEEESKDYLMHIA
  D39             KGTVSIATILLIPSNLEQEYPLLLFLVAGVTLVSFLTGLLILPHLSDEEEESKDYLMHIA
  D39V            KGTVSIATILLIPSNLEQEYPLLLFLVAGVTLVSFLTGLLILPHLSDEEEESKDYLMHIA
  EF3030          KGTVSIATILLIPSNLEQEYPLLLFLVAGVTLVSFLTGLLVLPHLSDEEEESKDYLMHIA
                  ****************************************:*******************
  
  TIGR4           ILNEVTLELEKELEDTRNKLPLYAAIDNYHGRIENLILSQENQDDQEDWAALKLLILSIE
  D39             ILNEVTLELEKELEDTRNKLPLYAAIDNYHGRIENLILSQENQDDQEDWAALKLLILSIE
  D39V            ILNEVTLELEKELEDTRNKLPLYAAIDNYHGRIENLILSQENQDDQEDWAALKLLILSIE
  EF3030          ILNEVTLELEKELEDTRNKLPLYAAIDNYHGRIENLILSQENQDDQEDWAALKLLILSIE
                  ************************************************************
  
  TIGR4           SDGLEQAYEEGNISNRAYRVYQRYLKNIEQGINRKLASRLTYYFLVSLRILRFLLHEVFT
  D39             SDGLEQAYEEGNISNRAYRVYQRYLKNIEQGINRKLASRLTYYFLVSLRILRFLLHEVFT
  D39V            SDGLEQAYEEGNISNRAYRVYQRYLKNIEQGINRKLASRLTYYFLVSLRILRFLLHEVFT
  EF3030          SDGLEQAYEKGNISNRAYRVYQRYLKNIEQGINRKLASRLTYYFLVSLRILRFLLHEVFT
                  *********:**************************************************
  
  TIGR4           LGKTFRSWKNKEQSRLRALDYDQIAELYLANTEMIIESLENLKGVYRRSLISFMQESRLR
  D39             LGKTFRSWKDKEQSRLRALDYDQIAELYLANTEMIIESLENLKGVYRRSLISFMQESRLR
  D39V            LGKTFRSWKDKEQSRLRALDYDQIAELYLANTEMIIESLENLKGVYRRSLISFMQESRLR
  EF3030          LGKTFRSWKNKEQSRLRALDYDQIAELYLANTEMIIESLENLKGVYRRSLISFMQESRLR
                  *********:**************************************************
  
  TIGR4           ETAIISSGAFVERVINRVKPNNIDEMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNN
  D39             ETTIISSGAFVERVINRVKPNNINEMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNN
  D39V            ETTIISSGAFVERVINRVKPNNINEMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNN
  EF3030          ETAIISSGAFVERVINRVKPNNIDEMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNN
                  **:********************:************************************
  
  TIGR4           LENYSLKEAANTLPYDMVELVRRN
  D39             LENYSLKEAANTLPYDMVELVRRN
  D39V            LENYSLKEAANTLPYDMVELVRRN
  EF3030          LENYSLKEAANTLPYDMVELVRRN
                  ************************