PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002236000
• symbol^?: pcrA
• synonym:
• description^?: DNA helicase PcrA

  descriptions from strain specific annotations:

  • DNA helicase PcrA
  • ATP-dependent DNA helicase PcrA
  • putative ATP-dependent DNA helicase
  • DNA helicase
  • ATP-dependent DNA helicase
  • ATP-dependent DNA helicase UvrD/PcrA
  • Superfamily I DNA and RNA helicase
• strand^?: +
• coordinates^?: 2691099..2693390
• occurrence^?: in 100% of 41 strains

⊟Orthologs

TIGR4:
SP_RS05385 (pcrA)
D39:
SPD_RS05235 (pcrA)
D39V:
SPV_RS05105 (pcrA)
Hungary19A-6:
SPH_RS05720 (pcrA)
EF3030:
EF3030_RS05900 (pcrA)
670-6B:
SP670_RS06170 (pcrA)
6A-10:
HKM25_RS05205 (pcrA)
70585:
SP70585_RS05780 (pcrA)
A026:
T308_RS05340 (pcrA)
A66:
A66_RS04965 (pcrA)
AP200:
SPAP_RS05480 (pcrA)
ASP0581:
EL334_RS05365 (pcrA)
ATCC 49619:
EL263_RS05420 (pcrA)
ATCC 700669:
SPN23F_RS05140 (pcrA)
BVJ1JL:
JN057_RS05555 (pcrA)
CGSP14:
SPCG_RS06165 (pcrA)
G54:
SPG_RS05075 (pcrA)
gamPNI0373:
HMPREF1038_RS05385 (pcrA)
HU-OH:
EL271_RS05205 (pcrA)
Hu15:
SPNHU15_RS05240 (pcrA)
Hu17:
SPNHU17_RS05165 (pcrA)
INV104:
INV104_RS05445 (pcrA)
INV200:
SPNINV200_RS05980 (pcrA)
JJA:
SPJ_RS05130 (pcrA)
MDRSPN001:
MDRSPN_RS04905 (pcrA)
NCTC7466:
DQM66_RS05115 (pcrA)
NU83127:
EL277_RS05475 (pcrA)
OXC141:
SPNOXC_RS05365 (pcrA)
P1031:
SPP_RS05415 (pcrA)
R6:
SPR_RS04980 (pcrA)
SP49:
BMJ42_RS05930 (pcrA)
SPN032672:
SPN032672_RS00320 (pcrA)
SPN034156:
SPN034156_RS00420 (pcrA)
SPN034183:
SPN034183_RS05385 (pcrA)
SPN994038:
SPN994038_RS05290 (pcrA)
SPN994039:
SPN994039_RS05295 (pcrA)
SPNA45:
SPNA45_RS07760 (pcrA)
ST556:
MYY_RS05820 (pcrA)
Taiwan19F-14:
SPT_RS05610 (pcrA)
TCH8431/19A:
HMPREF0837_RS06675 (pcrA)
Xen35:
CXP32_RS05435 (pcrA)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKLVNPWNILAITF
  D39             MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKLVNPWNILAITF
  D39V            MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKLVNPWNILAITF
  Hungary19A-6    MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKLVNPWNILAITF
  EF3030          MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKLVNPWNILAITF
                  ************************************************************
  
  TIGR4           TNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHIGYNRNFTIVDPGEQRTLM
  D39             TNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHIGYNRNFTIVDPGEQRTLM
  D39V            TNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHIGYNRNFTIVDPGEQRTLM
  Hungary19A-6    TNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHIGYNRNFTIVDPGEQRTLM
  EF3030          TNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHIGYNRNFTIVDPGEQRTLM
                  ************************************************************
  
  TIGR4           KRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQAGDMYTQIVAQCYTAYQKELR
  D39             KRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQAGDMYTQIVAQCYTAYQKELR
  D39V            KRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQAGDMYTQIVAQCYTAYQKELR
  Hungary19A-6    KRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQAGDMYTQIVAQCYTTYQKELR
  EF3030          KRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQAGDMYTQIVAQCYTAYQKELR
                  *****************************************************:******
  
  TIGR4           QSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVDEYQDTNHAQYQLVKLLASRFKN
  D39             QSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVDEYQDTNHAQYQLVKLLASRFKN
  D39V            QSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVDEYQDTNHAQYQLVKLLASRFKN
  Hungary19A-6    QSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVDEYQDTNHAQYQLVKLLASRFKN
  EF3030          QSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVDEYQDTNHAQYQLVKLLASRFKN
                  ************************************************************
  
  TIGR4           ICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVLLEENYRSTKTILQAANEVIKNNKN
  D39             ICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVLLEENYRSTKTILQAANEVIKNNKN
  D39V            ICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVLLEENYRSTKTILQAANEVIKNNKN
  Hungary19A-6    ICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVLLEENYRSTKTILQAANEVIKNNKN
  EF3030          ICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVLLEENYRSTKTILQAANEVIKNNKN
                  ************************************************************
  
  TIGR4           RRPKNLWTQNADGEQIVYYRADDELDEAVFVARTIDELSRSQNFLHKDFAVLYRTNAQSR
  D39             RRPKNLWTQNADGEQIVYYRADDELDEAVFVARTIDELSRSQNFLHKDFAVLYRTNAQSR
  D39V            RRPKNLWTQNADGEQIVYYRADDELDEAVFVARTIDELSRSQNFLHKDFAVLYRTNAQSR
  Hungary19A-6    RRPKNLWTQNADGEQIVYYRADDELDEAVFVVRTIDELSRSQNFLHKDFAVLYRTNAQSR
  EF3030          RRPKNLWTQNADGEQIVYYRADDELDEAVFVARTIDELSRSQNFLHKDFAVLYRTNAQSR
                  *******************************.****************************
  
  TIGR4           TIEEALLKSNIPYTMVGGTKFYSRKEIRDIIAYLNLIANLSDNISFERIINEPKRGIGLG
  D39             TIEEALLKSNIPYTMVGGTKFYSRKEIRDIIAYLNLIANLSDNISFERIINEPKRGIGLG
  D39V            TIEEALLKSNIPYTMVGGTKFYSRKEIRDIIAYLNLIANLSDNISFERIINEPKRGIGLG
  Hungary19A-6    TIEEALLKSNIPYTMVGGTKFYSRKEIRDIIAYLNLIANLSDNISFERIINEPKRGIGLG
  EF3030          TIEEALLKSNIPYTMVGGTKFYSRKEIRDIIAYLNLIANLSDNISFERIINEPKRGIGLG
                  ************************************************************
  
  TIGR4           TVEKIRDFANLQNMSMLDASANIMLSGIKGKAAQSIWDFANMMLDLREQLDHLSITELVE
  D39             TVEKIRDFANLQNMSMLDASANIMLSGIKGKAAQSIWDFANMMLDLREQLDHLSITELVE
  D39V            TVEKIRDFANLQNMSMLDASANIMLSGIKGKAAQSIWDFANMMLDLREQLDHLSITELVE
  Hungary19A-6    TVEKIRDFANLQNMSMLDASANIMLSGIKGKAAQSIWDFANMMLDLREQLDHLSITELVE
  EF3030          TVEKIRDFANLQNMSMLDASANIMLSGIKGKAAQSIWDFANMMLDLREQLDHLSITELVE
                  ************************************************************
  
  TIGR4           SVLEKTGYVDILNSQATLESKARVENIEEFLSVTKNFDDTTDVTEEETGLDKLSRFLNDL
  D39             SVLEKTGYVDILNAQATLESKARVENIEEFLSVTKNFDDTTDVTEEETGLDKLSRFLNDL
  D39V            SVLEKTGYVDILNAQATLESKARVENIEEFLSVTKNFDDTTDVTEEETGLDKLSRFLNDL
  Hungary19A-6    SVLEKTGYVDILNAQATLESKARVENIEEFLSVTKNFDDTTDVTEEETGLDKLSRFLNDL
  EF3030          SVLEKTGYVDILNAQATLESKARVENIEEFLSVTKNFDDTTDVTEEETGLDKLSRFLNDL
                  *************:**********************************************
  
  TIGR4           ALIADTDSGSQETSEVTLMTLHAAKGLEFPVVFLIGMEENVFPLSRATEDSDELEEERRL
  D39             ALIADTDSGSQETSEVTLMTLHAAKGLEFPVVFLIGMEENVFPLSRATEDPDELEEERRL
  D39V            ALIADTDSGSQETSEVTLMTLHAAKGLEFPVVFLIGMEENVFPLSRATEDPDELEEERRL
  Hungary19A-6    ALIADTDSGSQETSEVTLMTLHAAKGLEFPVVFLIGMEENVFPLSRATEDPDELEEERRL
  EF3030          ALIADTDSGSQETSEVTLMTLHAAKGLEFPVVFLIGMEENVFPLSRATEDPDELEEERRL
                  **************************************************.*********
  
  TIGR4           AYVGITRAEKILYLTNANSRLLFGRTNYNRPTRFINEISSDLLEYQGLARPANTSFKASY
  D39             AYVGITRAEKILYLTNANSRLLFGRTNYNRPTRFINEISSDLLEYQGLARPANTSFKASY
  D39V            AYVGITRAEKILYLTNANSRLLFGRTNYNRPTRFINEISSDLLEYQGLARPANTSFKASY
  Hungary19A-6    AYVGITRAEKILYLTNANSRLLFGRTNYNRPTRFINEISSDLLEYQGLARPANTSFKASY
  EF3030          AYVGITRAEKILYLTNANSRLLFGRTNYNRPTRFINEISSDLLEYQGLARPANTSFKASY
                  ************************************************************
  
  TIGR4           SSGSISFGQGMSLAQALQDRKRGAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALH
  D39             SSGSISFGQGMSLAQALQDRKRGAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALH
  D39V            SSGSISFGQGMSLAQALQDRKRGAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALH
  Hungary19A-6    SSGSISFGQGMSLAQALQDRKRGAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALH
  EF3030          SSGSISFGQGMSLAQALQDRKRGAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALH
                  ********************************************.***************
  
  TIGR4           KKWGEGTVLEVSGSGARQELKINFPEVGLKKLLASVAPIEKKI
  D39             KKWGEGTVLEVSGSGARQELKINFPEVGLKKLLASVAPIEKKI
  D39V            KKWGEGTVLEVSGSGARQELKINFPEVGLKKLLASVAPIEKKI
  Hungary19A-6    KKWGEGTVLEVSGSGARQELKINFPEVGLKKLLASVAPIEKKI
  EF3030          KKWGEGTVLEVSGSGARQELKINFPEVGLKKLLASVAPIEKKI
                  *******************************************