PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002389000
• symbol^?: acoA
• synonym:
• description^?: thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha

  descriptions from strain specific annotations:

  • thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
  • putative pyruvate dehydrogenase E1 component,alpha subunit
  • pyruvate dehydrogenase E1 component subunit alpha
  • Acetoin dehydrogenase E1 component alpha-subunit
  • Acetoin:2,6-dichlorophenolindophenol
  • acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha
  • pyruvate dehydrogenase E1 subunit alpha
  • pyruvate dehydrogenase
  • TPP-dependent acetoin dehydrogenase alpha-subunit
  • acetoin:2%2C6-dichlorophenolindophenol oxidoreductase subunit alpha
  • acetoin dehydrogenase, E1 component, alpha subunit, putative
  • dehydrogenase E1 component
  • putative acetoin dehydrogenase, E1 component, alpha subunit
  • Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
  • thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein
  • TPP-dependent acetoin dehydrogenase alpha chain
  • TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit
• strand^?: -
• coordinates^?: 3053330..3054298
• occurrence^?: in 98% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS05740
(2)
D39:
SPD_RS05525
(2)
D39V:
SPV_RS04815
(19A)
Hungary19A-6:
—
(19F)
EF3030:
EF3030_RS05610
(6B)^?
670-6B:
SP670_RS05470
(6A)
6A-10:
HKM25_RS05480
(5)
70585:
SP70585_RS06060
(19F)
A026:
T308_RS05625
(3)
A66:
A66_RS05240
(11A)
AP200:
SPAP_RS05185
(12F)
ASP0581:
EL334_RS06055
(19F)
ATCC 49619:
EL263_RS05710
(23F)
ATCC 700669:
SPN23F_RS05425
(19F)
BM6001:
ODS73_RS06160
(1)
BVJ1JL:
JN057_RS05850
(14)
CGSP14:
SPCG_RS05870
(19F)
G54:
SPG_RS05365
(1)
gamPNI0373:
HMPREF1038_RS05090
(3)
HU-OH:
EL271_RS05900
(19A)
Hu15:
SPNHU15_RS05715
(19A)
Hu17:
SPNHU17_RS05640
(1)
INV104:
INV104_RS05815
(14)
INV200:
SPNINV200_RS05690
(14)
JJA:
SPJ_RS05415
(19F)
MDRSPN001:
MDRSPN_RS05195
(1)
NCTC7465:
AT689_RS08255
(2)
NCTC7466:
DQM66_RS04825
(4)
NU83127:
EL277_RS05760
(3)
OXC141:
SPNOXC_RS05650
(1)
P1031:
SPP_RS05985
(2)
R6:
SPR_RS05250
(19A)
SP49:
BMJ42_RS06190
(1)
SPN032672:
SPN032672_RS00685
(3)
SPN034156:
SPN034156_RS00705
(3)
SPN034183:
SPN034183_RS05665
(3)
SPN994038:
SPN994038_RS05570
(3)
SPN994039:
SPN994039_RS05575
(3)
SPNA45:
SPNA45_RS08040
(19F)
ST556:
MYY_RS06105
(19F)
Taiwan19F-14:
SPT_RS05895
(19A)
TCH8431/19A:
HMPREF0837_RS06390
(4)
Xen35:
CXP32_RS05795

⊟Genome Viewer

TIGR4
D39
D39V
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
  D39             MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
  D39V            MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
  EF3030          MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
                  ************************************************************
  
  TIGR4           LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
  D39             LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
  D39V            LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
  EF3030          LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
                  ************************************************************
  
  TIGR4           MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
  D39             MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
  D39V            MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
  EF3030          MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
                  ************************************************************
  
  TIGR4           ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
  D39             ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
  D39V            ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
  EF3030          ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
                  ************************************************************
  
  TIGR4           RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEEIQAQVKEAVEAS
  D39             RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEKIQAQVKEAVEAS
  D39V            RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEKIQAQVKEAVEAS
  EF3030          RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEEIQAQVKEAVEAS
                  ***********************************************:************
  
  TIGR4           VKFAEESPFPPLESAFEDIYAD
  D39             VKFAEESPFPPLESAFEDIYTD
  D39V            VKFAEESPFPPLESAFEDIYTD
  EF3030          VKFAEESPFPSLESAFEDIYAD
                  **********.*********:*