PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002659000
• symbol^?: alaS
• synonym:
• description^?: alanine--tRNA ligase

  descriptions from strain specific annotations:

  • alanine--tRNA ligase
  • alanyl-tRNA synthetase
  • alanyl-tRNA synthase
• strand^?: -
• coordinates^?: 3515457..3518075
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS06780 (alaS)
(2)
D39:
SPD_RS06500 (alaS)
(2)
D39V:
SPV_RS06495 (alaS)
(19A)
Hungary19A-6:
SPH_RS07320 (alaS)
(19F)
EF3030:
EF3030_RS06450 (alaS)
(6B)^?
670-6B:
SP670_RS04515 (alaS)
(6A)
6A-10:
HKM25_RS06420 (alaS)
(5)
70585:
SP70585_RS07045 (alaS)
(19F)
A026:
T308_RS04160 (alaS)
(3)
A66:
A66_RS06100 (alaS)
(11A)
AP200:
SPAP_RS06955 (alaS)
(12F)
ASP0581:
EL334_RS07070 (alaS)
(19F)
ATCC 49619:
EL263_RS06730 (alaS)
(23F)
ATCC 700669:
SPN23F_RS06815 (alaS)
(19F)
BM6001:
ODS73_RS07085 (alaS)
(1)
BVJ1JL:
JN057_RS06780 (alaS)
(14)
CGSP14:
SPCG_RS07100 (alaS)
(19F)
G54:
SPG_RS06610 (alaS)
(1)
gamPNI0373:
HMPREF1038_RS06700 (alaS)
(3)
HU-OH:
EL271_RS06785 (alaS)
(19A)
Hu15:
SPNHU15_RS06770 (alaS)
(19A)
Hu17:
SPNHU17_RS06695 (alaS)
(1)
INV104:
INV104_RS06755 (alaS)
(14)
INV200:
SPNINV200_RS06555 (alaS)
(14)
JJA:
SPJ_RS06370 (alaS)
(19F)
MDRSPN001:
MDRSPN_RS03745 (alaS)
(1)
NCTC7465:
AT689_RS07140 (alaS)
(2)
NCTC7466:
DQM66_RS06500 (alaS)
(4)
NU83127:
EL277_RS06840 (alaS)
(3)
OXC141:
SPNOXC_RS06540 (alaS)
(1)
P1031:
SPP_RS06910 (alaS)
(2)
R6:
SPR_RS06200 (alaS)
(19A)
SP49:
BMJ42_RS07185 (alaS)
(1)
SPN032672:
SPN032672_RS01635 (alaS)
(3)
SPN034156:
SPN034156_RS01595 (alaS)
(3)
SPN034183:
SPN034183_RS06555 (alaS)
(3)
SPN994038:
SPN994038_RS06460 (alaS)
(3)
SPN994039:
SPN994039_RS06465 (alaS)
(3)
SPNA45:
SPNA45_RS04680 (alaS)
(19F)
ST556:
MYY_RS04635 (alaS)
(19F)
Taiwan19F-14:
SPT_RS04420 (alaS)
(19A)
TCH8431/19A:
HMPREF0837_RS05585 (alaS)
(4)
Xen35:
CXP32_RS06850 (alaS)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPEN
  D39             MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPEN
  D39V            MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPEN
  Hungary19A-6    MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPEN
  EF3030          MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPEN
                  ************************************************************
  
  TIGR4           PRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAITWAYELLTSPEWFDF
  D39             PRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAITWAYELLTSPEWFDF
  D39V            PRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAITWAYELLTSPEWFDF
  Hungary19A-6    PRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAITWAYELLTSPEWFDF
  EF3030          PRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAITWAYELLTSPEWFDF
                  ************************************************************
  
  TIGR4           PAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFD
  D39             PAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFD
  D39V            PAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFD
  Hungary19A-6    PAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFD
  EF3030          PAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFD
                  ************************************************************
  
  TIGR4           PENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAV
  D39             PENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAV
  D39V            PENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAV
  Hungary19A-6    PENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAV
  EF3030          PENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAV
                  ************************************************************
  
  TIGR4           IQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNE
  D39             IQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNE
  D39V            IQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNE
  Hungary19A-6    IQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNE
  EF3030          IQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNE
                  ************************************************************
  
  TIGR4           GRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKRDFIEKIVKSEE
  D39             GRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKRDFIEKIVKSEE
  D39V            GRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKRDFIEKIVKSEE
  Hungary19A-6    GRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKRDFIEKIVKSEE
  EF3030          GRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKRDFIEKIVKSEE
                  ************************************************************
  
  TIGR4           ESFARTLHSGQHFAQGIVADLKEKGQSVIAGSDVFKLYDTYGFPVELTEEIAEEAGMTVD
  D39             ESFARTLHSGQHFAQGIVADLKEKGQSVIAGQDVFKLYDTYGFPVELTEEIAEEAGMTVD
  D39V            ESFARTLHSGQHFAQGIVADLKEKGQSVIAGQDVFKLYDTYGFPVELTEEIAEEAGMTVD
  Hungary19A-6    ESFARTLHSGQHFAQGIVADLKEKGQSVIAGQDVFKLYDTYGFPVELTEEIAEEAGMTVD
  EF3030          ESFARTLHSGQHFAQGIVADLKEKGQSVIAGQDVFKLYDTYGFPVELTEEIAEEAGMTVD
                  *******************************.****************************
  
  TIGR4           REGFEAAMKEQQERARASAVKGGSMGMQNETLQNITVESVFNYNASQLSSKLVAIVADNA
  D39             REGFEAAMKEQQERARASAVKGGSMGMQNETLQNITVESVFNYNTSQLSSKLVAIVADNA
  D39V            REGFEAAMKEQQERARASAVKGGSMGMQNETLQNITVESVFNYNTSQLSSKLVAIVADNA
  Hungary19A-6    REGFEAAMKEQQERARASAVKGGSMGMQNETLQNITVESVFNHNASQLSSKLVAIVADNA
  EF3030          REGFEAAMKEQQERARASAVKGGSMGMQNETLQNITVESVFNYNASQLSSKLVAIVADNA
                  ******************************************:*:***************
  
  TIGR4           EVGAVSEGTASLIFAETSFYAEMGGQVADYGQILDESGKVVATVTNVQKAPNGQALHTVE
  D39             EVGAVSEGTASLIFAETSFYAEMGGQVADYGQILDESGKIVATVTNVQKAPNGQALHTVE
  D39V            EVGAVSEGTASLIFAETSFYAEMGGQVADYGQILDESGKIVATVTNVQKAPNGQALHTVE
  Hungary19A-6    EVEAVSEGTTSLIFAETPFYAEMGGQVADHGQILDESGKVVATVTNVQKAPNGQALHTVE
  EF3030          EVEAVSEGTTSLIFAETPFYAEMGGQVADHGQILDESGKVVATVTNVQKAPNGQALHTVE
                  ** ******:*******.***********:*********:********************
  
  TIGR4           VLAPLALNQEYTLAIDSNRRHRVMKNHTATHLLHAALHNILGNHATQAGSLNEVEFLRFD
  D39             VLAPLALNQEYTLAIDSNRRHRVMKNHTATHLLHAALHNILGNHATQAGSLNEVEFLRFD
  D39V            VLAPLALNQEYTLAIDSNRRHRVMKNHTATHLLHAALHNILGNHATQAGSLNEVEFLRFD
  Hungary19A-6    VLAPLALNQEYTLAIDSNRRHRVMKNHTATHLLHAALHNILGNHATQAGSLNEVEFLRFD
  EF3030          VLAPLALNQEYTLAIDSNRRHRVMKNHTATHLLHAALHNILGNHATQAGSLNEVEFLRFD
                  ************************************************************
  
  TIGR4           FTHFQAVTAEELRAIEQQVNEKIWEALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVT
  D39             FTHFQAVTAEELRAIEQQVNEKIWEALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVT
  D39V            FTHFQAVTAEELRAIEQQVNEKIWEALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVT
  Hungary19A-6    FTHFQAVTAEELRAIEQQVNEKIWEALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVT
  EF3030          FTHFQAVTAEELRAIEQQVNEKIWEALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVT
                  ************************************************************
  
  TIGR4           IGDYSIELCGGTHVDNTSEIGLFKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAI
  D39             IGDYSIELCGGTHVDNTSEIGLFKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAI
  D39V            IGDYSIELCGGTHVDNTSEIGLFKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAI
  Hungary19A-6    IGDYSIELCGGTHVGNTSEIGLFKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAV
  EF3030          IGDYSIELCGGTHVGNTSEIGLFKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAV
                  **************.********************************************:
  
  TIGR4           AATLKAPQVKEVPHKVEGLQEQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIAS
  D39             AATLKAPQVKEVPHKVEGLQEQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIAS
  D39V            AATLKAPQVKEVPHKVEGLQEQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIAS
  Hungary19A-6    AATLKAPQVKEVPHKVEGLQEQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIAS
  EF3030          AATLKAPQVKEVPHKVEGLQEQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIAS
                  ************************************************.***********
  
  TIGR4           QVSVSDAGALRTFADNWKQKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPII
  D39             QVSVSDAGALRTFADNWKQKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPII
  D39V            QVSVSDAGALRTFADNWKQKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPII
  Hungary19A-6    QVSVSDAGALRTFADNWKQKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPII
  EF3030          QVSVSDAGALRTFADNWKQKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPII
                  ************************************************************
  
  TIGR4           DGRGGGKPDMAMAGGSNQPKIQELLDAVAGKL
  D39             DGRGGGKPDMAMAGGSNQPKIQELLDAVAGKL
  D39V            DGRGGGKPDMAMAGGSNQPKIQELLDAVAGKL
  Hungary19A-6    DGRGGGKPDMAMAGGSNQPKIQELLDAVAGKL
  EF3030          DGRGGGKPDMAMAGGSNQAKIQELLDAVAGKL
                  ******************.*************