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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_0024 [new locus tag: SP670_RS00100 ]
  • pan locus tag?: PNEUPAN000239000
  • symbol: SP670_0024
  • pan gene symbol?: —
  • synonym:
  • product: cI repressor

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_0024 [new locus tag: SP670_RS00100 ]
  • symbol: SP670_0024
  • product: cI repressor
  • replicon: chromosome
  • strand: +
  • coordinates: 14702..15418
  • length: 717
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP002176 (14702..15418) NCBI
  • BioCyc: see SP670_RS00100
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGCGGACAATATCAAAAGACTTTTAAGTGCAAAAGGTTTAAACCCTCGTCAATTAGCT
    ATTGCATTAGATTTTAAGTATACAACCGTCAACGATTGGGTAAATGCTAAAACTTACCCA
    CGTATAGATAAAATCGAAATGCTGGCTAATTTTTTCAACGTTTCAAAGTCTGACTTAGTA
    GAAAATAAAAACGCAGAAACACCTACCACTTCCCCCATCCAATCCATCTATGACCAACTC
    ACTCCACCAAGACAAGAAAAAGCCTTGACTTATCTTAAAAAGCAGCTGCTGGAGCAGAAA
    AACGAAAACATAGTATCAGAAAACATTATCAGTCTGGACGACTACAGAGAAAGCAAGACG
    CTCCCTGTTATCGGAGTTGTAACCGCCGGAAACGGGATAACCCAAGACGATAACCTAAAC
    ATGGAAAAATGCTTTTATACTGATGAAATACCAGACGACTACGACGCTATCGCTTATGTT
    GTCGGCAACTCTATGGAGCCAAAGATAAAGAATGGCGACTACCTATTTATCAAGAATACA
    CCTCAAGTTGACTATAACACTATCGGTATCTTCCAAGTAGACGGCGCTAACTACGTCAAG
    AAACTGCGTCAAGGGTATTTAGAAAGCCTTAACCCTGATTGTGCTGATATTCAACTAGAC
    GAAAGCAACGATATACGCACCATCGGCGAAGTCGTGAGTATATATAGAGAGAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    717

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_0024 [new locus tag: SP670_RS00100 ]
  • symbol: SP670_0024
  • description: cI repressor
  • length: 238
  • theoretical pI: 4.41137
  • theoretical MW: 27020.2
  • GRAVY: -0.507983

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 37.4)
    Signal transduction Regulatory functions DNA interactions repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 37.4)
    and 5 more
    signal peptidase I (TIGR02228; EC 3.4.21.89; HMM-score: 18.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal peptidase I (TIGR02227; EC 3.4.21.89; HMM-score: 16.3)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage-associated protein, BcepMu gp16 family (TIGR04111; HMM-score: 12.7)
    Cellular processes Cellular processes Detoxification nickel-type superoxide dismutase maturation protease (TIGR02754; EC 3.4.21.-; HMM-score: 12.2)
    Genetic information processing Protein fate Protein modification and repair nickel-type superoxide dismutase maturation protease (TIGR02754; EC 3.4.21.-; HMM-score: 12.2)
  • TheSEED  :
    • Phage CI-like repressor
  • PFAM:
    Peptidase_SF (CL0299) Peptidase_S24; Peptidase S24-like (PF00717; HMM-score: 70.1)
    and 5 more
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 28.3)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 25.4)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 15.4)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 12.9)
    HTH_29; Winged helix-turn helix (PF13551; HMM-score: 12.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9949
    • Cytoplasmic Membrane Score: 0.0009
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0042
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007175
    • TAT(Tat/SPI): 0.000326
    • LIPO(Sec/SPII): 0.000743
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM90106 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MADNIKRLLSAKGLNPRQLAIALDFKYTTVNDWVNAKTYPRIDKIEMLANFFNVSKSDLVENKNAETPTTSPIQSIYDQLTPPRQEKALTYLKKQLLEQKNENIVSENIISLDDYRESKTLPVIGVVTAGNGITQDDNLNMEKCFYTDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTPQVDYNTIGIFQVDGANYVKKLRQGYLESLNPDCADIQLDESNDIRTIGEVVSIYREN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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