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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_0025 [new locus tag: SP670_RS00105 ]
  • pan locus tag?: PNEUPAN000245000
  • symbol: SP670_0025
  • pan gene symbol?: dinD
  • synonym:
  • product: DNA-damage-inducible protein D

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP670_0025 [new locus tag: SP670_RS00105 ]
  • symbol: SP670_0025
  • product: DNA-damage-inducible protein D
  • replicon: chromosome
  • strand: +
  • coordinates: 16644..17498
  • length: 855
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP002176 (16644..17498) NCBI
  • BioCyc: see SP670_RS00105
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGGAACTCCAACAGTACGATGAATTAACTTTTGAAAATATCAAACACATAGACGAAAAT
    GGAGTAGAATTTTGGTACGCTCGGGACTTACAAAAGACCCTTGAGTATACAGAATGGAGA
    AACTTTCTTCTAGTAATTGATAAGGCAAAGATAGCTTGCGATACCGCTAAAAACCCCATT
    GTAGAGCATTTTGTTGACGTCAACAAGTCAATTCCAAACGGTTATAACACAACAAGAGAT
    ATCAAAGATTTTAAACTTACCCGTTACGCTTGTTACCTTATTGTCCAAAATGGTGACCCA
    CGAAAAGAAGTTATAGCACTTGGCCAAACCTATTTCGCGTTGAAAACTCGTCAACAAGAG
    CTACAAGAAAACTTTGACAATCTTACCGAAGAACAGAAACGCCTTGCTATCCGTGACGAA
    ATTAAACATCACAATAAATCATTATCTGAGTCTGCTGGCAATGCTGGCGTTAAGAACTTT
    GGAAGATTTCACAACTCAGGATACAAGGGGTTATATGGTGGGCTAACTATGCAGGATATT
    CATAACCTCAAAGAACTAAACGAAGGGGAGCATATTCTGGATTTTATGGGGAGTGCTGAA
    TTAGCTGCTAATTTATTCCGTGCCACTCAGACCGACGAAGTTCTACGACGTAGAAACATA
    AAAGGCGAAGATCTCGCAAATGATACCCATTTCAACGTAGGCCGAACCATTAGAAATACC
    ATGAAAGAACTTGGAACAACCATGCCGGAGAATCTCCCTGCTCCTCGTGAAAGTATACAA
    GAGTTGAAAAGCAAACAGAAAGAACTTGAAAAACAAGATGATAATAACCAACTTTCGCTC
    TTTGATGATATGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    855

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP670_0025 [new locus tag: SP670_RS00105 ]
  • symbol: SP670_0025
  • description: DNA-damage-inducible protein D
  • length: 284
  • theoretical pI: 5.46146
  • theoretical MW: 32949.7
  • GRAVY: -0.802465

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • DNA-damage-inducible protein D
  • PFAM:
    no clan defined Bro-N; BRO family, N-terminal domain (PF02498; HMM-score: 27.9)
    and 4 more
    CUPID; Cytohesin Ubiquitin Protein Inducing Domain (PF11819; HMM-score: 18)
    SKA2; Spindle and kinetochore-associated protein 2 (PF16740; HMM-score: 17)
    GPS2_interact; G-protein pathway suppressor 2-interacting domain (PF15784; HMM-score: 9.8)
    FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 9.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8354
    • Cytoplasmic Membrane Score: 0.0042
    • Cell wall & surface Score: 0.0045
    • Extracellular Score: 0.1559
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004564
    • TAT(Tat/SPI): 0.000802
    • LIPO(Sec/SPII): 0.001071
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM90107 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MELQQYDELTFENIKHIDENGVEFWYARDLQKTLEYTEWRNFLLVIDKAKIACDTAKNPIVEHFVDVNKSIPNGYNTTRDIKDFKLTRYACYLIVQNGDPRKEVIALGQTYFALKTRQQELQENFDNLTEEQKRLAIRDEIKHHNKSLSESAGNAGVKNFGRFHNSGYKGLYGGLTMQDIHNLKELNEGEHILDFMGSAELAANLFRATQTDEVLRRRNIKGEDLANDTHFNVGRTIRNTMKELGTTMPENLPAPRESIQELKSKQKELEKQDDNNQLSLFDDM

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]