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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_0047 [new locus tag: SP670_RS00230 ]
  • pan locus tag?: PNEUPAN000397000
  • symbol: SP670_0047
  • pan gene symbol?: —
  • synonym:
  • product: phage transcriptional repressor

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_0047 [new locus tag: SP670_RS00230 ]
  • symbol: SP670_0047
  • product: phage transcriptional repressor
  • replicon: chromosome
  • strand: -
  • coordinates: 41768..42502
  • length: 735
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP002176 (41768..42502) NCBI
  • BioCyc: see SP670_RS00230
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAATGTCGGAGAAAGAATAAAACAACGTCGAAAAGCGTTGAAAATGTCTGCGGACGAG
    CTTGCAGAAAGTGTAGGTGTCTCTCGTTCTACTATTTTTAGGTACGAAAAAGGAGATATT
    GAAAAAGTTGGACCTGAAGTATTAAAAAAAATCGCTGACAAATTAAATGTATCACCTGGA
    GACTTGATGGGATGGGAAGACAATCAACAAGAATTGAAAATCCCAACCTCCCCGTTGGTT
    CACAAAATTACTGAAAAGGTTGTCAAACTATCAACTCCGAGAAAACAAAAGGTTCTTAAC
    TACGCTAACGAACAATTGAAAGAGCAAAATAATAAAGTAATCACAATTGAGGAAAAGCTT
    TTTGAATATCGTGTTTTTGAAAAACTTTCAGCTGGTACTGGATTCTCATACTTCAACGAT
    GGGAACTATGACACTGTTTTTTACGACAAAGACCTAGACCACGATTTTGCTTCTTGGGTT
    TTCGGAGATTCCATGGAGCCTAAGTACATGAATGGAGAGGTCGTTCTCATCAAAGAAACA
    GGTTTTGACTACGATGGTGCCATTTATGCAGTTGACTGGGATGGTCAAACTTATATTAAA
    AAAGTCTATAAAGAAAAAGACGGTCTTAGACTCGTCTCTATCAATAACAAATATAAAGAT
    AAATTCGCACCATTTGAAGAAGATCCAAGGATTATTGGGAAAATAGTCGGAAACTTCATG
    CCAATTGAAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    735

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_0047 [new locus tag: SP670_RS00230 ]
  • symbol: SP670_0047
  • description: phage transcriptional repressor
  • length: 244
  • theoretical pI: 5.54279
  • theoretical MW: 28119.8
  • GRAVY: -0.62541

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 26.5)
    Signal transduction Regulatory functions DNA interactions repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 26.5)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 26.5)
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 26.5)
    and 10 more
    Unknown function General mobile mystery protein A (TIGR02612; HMM-score: 15.9)
    signal peptidase I (TIGR02228; EC 3.4.21.89; HMM-score: 15.8)
    probable regulatory domain (TIGR03879; HMM-score: 15.8)
    Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 13.5)
    Genetic information processing Mobile and extrachromosomal element functions Other addiction module antidote protein, HigA family (TIGR02607; HMM-score: 13.3)
    Signal transduction Regulatory functions DNA interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 13.3)
    Signal transduction Regulatory functions Protein interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 13.3)
    Cellular processes Cellular processes Pathogenesis type VI secretion system peptidoglycan-associated domain (TIGR03350; HMM-score: 12.6)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VI secretion system peptidoglycan-associated domain (TIGR03350; HMM-score: 12.6)
    Signal transduction Regulatory functions DNA interactions mycofactocin system transcriptional regulator (TIGR03968; HMM-score: 12.6)
  • TheSEED  :
    • Pleiotropic regulator of exopolysaccharide synthesis, competence and biofilm formation Ftr, XRE family
  • PFAM:
    Peptidase_SF (CL0299) Peptidase_S24; Peptidase S24-like (PF00717; HMM-score: 81.1)
    and 24 more
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 57.1)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 47.5)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 43.2)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 42.2)
    HTH_11; HTH domain (PF08279; HMM-score: 22)
    HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 21.3)
    HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 18.2)
    Xre-like-HTH; Antitoxin Xre-like helix-turn-helix domain (PF20432; HMM-score: 18.2)
    TetR_N; Bacterial regulatory proteins, tetR family (PF00440; HMM-score: 17.3)
    HTH_22; HTH domain (PF13309; HMM-score: 17.2)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 16.1)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 15.6)
    HTH_25; Helix-turn-helix domain (PF13413; HMM-score: 15.2)
    HTH_Tnp_1_2; Helix-turn-helix of insertion element transposase (PF13022; HMM-score: 15)
    HTH_6; Helix-turn-helix domain, rpiR family (PF01418; HMM-score: 14.2)
    MerR_1; MerR HTH family regulatory protein (PF13411; HMM-score: 14.1)
    HTH_AsnC-type; AsnC-type helix-turn-helix domain (PF13404; HMM-score: 13.8)
    HTH_10; HTH DNA binding domain (PF04967; HMM-score: 13.5)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 13.4)
    HTH_29; Winged helix-turn helix (PF13551; HMM-score: 13.1)
    MqsA_antitoxin; Antitoxin component of bacterial toxin-antitoxin system, MqsA (PF15731; HMM-score: 13.1)
    HTH_IclR; IclR helix-turn-helix domain (PF09339; HMM-score: 12.7)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 12.7)
    MerR; MerR family regulatory protein (PF00376; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9798
    • Cytoplasmic Membrane Score: 0.0069
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.013
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006862
    • TAT(Tat/SPI): 0.001128
    • LIPO(Sec/SPII): 0.001325
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM90129 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNVGERIKQRRKALKMSADELAESVGVSRSTIFRYEKGDIEKVGPEVLKKIADKLNVSPGDLMGWEDNQQELKIPTSPLVHKITEKVVKLSTPRKQKVLNYANEQLKEQNNKVITIEEKLFEYRVFEKLSAGTGFSYFNDGNYDTVFYDKDLDHDFASWVFGDSMEPKYMNGEVVLIKETGFDYDGAIYAVDWDGQTYIKKVYKEKDGLRLVSINNKYKDKFAPFEEDPRIIGKIVGNFMPIEN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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