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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_2056 [new locus tag: SP670_RS10355 ]
  • pan locus tag?: PNEUPAN003574000
  • symbol: purR
  • pan gene symbol?: purR
  • synonym:
  • product: pur operon repressor

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_2056 [new locus tag: SP670_RS10355 ]
  • symbol: purR
  • product: pur operon repressor
  • replicon: chromosome
  • strand: -
  • coordinates: 1920334..1921161
  • length: 828
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAATTAAGAAGAAGTGATCGGATGGTTGTCATTTCCAACTATTTGATTAATAATCCT
    TATAAACTAACTAGTCTCAATACTTTTGCTGAAAAGTATGAGTCTGCTAAATCATCCATC
    TCAGAAGATATCGTCATTATCAAACGCGCCTTTGAGGAAATTGAAATCGGTCATATCCAG
    ACAGTGACTGGGGCTGGCGGAGGTGTCATCTTCACACCGTCTATTTCGAGTCAGGATGCT
    AAGGAAATGGTTGAAGACTTGCGTACCAAGTTGTCAGAAAGTGACCGTATCTTGCCAGGT
    GGTTATATCTATCTGTCTGATTTGCTTAGCACACCAGCCATCTTGAAAAATATTGGTCGT
    ATTATTGCCAAAAGCTTTATGGACCAAAAAATTGACGCGGTTATGACCGTAGCAACTAAG
    GGTGTGCCACTTGCAAATGCAGTTGCCAATGTCCTCAATGTCTCTTTTGTCATTGTGCGC
    CGTGACCTGAAAATTACCGAAGGTTCAACTGTTAGCGTCAACTATGTTTCAGGTTCAAGT
    GGTGACCGTATCGAGAAAATGTTCCTTTCAAAACGTAGTCTTAAGGCAGGCAGCCGTGTC
    TTGATTGTGGATGACTTCTTGAAAGGTGGCGGAACGGTCAACGGTATGATTAGTCTCTTG
    CGCGAGTTCGACTCAGAACTGGCAGGTGTAGCGGTCTTTGCGGACAATGCCCAAGAAGAA
    CGTGAAAAGCAGTTTGACTACAAGTCACTCTTGAAGGTAACTAATATTGATGTCAAGAAC
    CAAGCCATCGATGTTGAGGTTGGCAATATCTTTGACGAAGATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    828

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_2056 [new locus tag: SP670_RS10355 ]
  • symbol: PurR
  • description: pur operon repressor
  • length: 275
  • theoretical pI: 5.52757
  • theoretical MW: 30226.5
  • GRAVY: -0.0469091

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis pur operon repressor PurR (TIGR01743; HMM-score: 452)
    Signal transduction Regulatory functions DNA interactions pur operon repressor PurR (TIGR01743; HMM-score: 452)
    and 5 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine phosphoribosyltransferase (TIGR01090; EC 2.4.2.7; HMM-score: 61.9)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides xanthine phosphoribosyltransferase (TIGR01744; EC 2.4.2.22; HMM-score: 55.3)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR00336; EC 2.4.2.10; HMM-score: 44.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 31.9)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 16.1)
  • TheSEED  :
    • Pur operon repressor PurR
    Nucleosides and Nucleotides Purines De Novo Purine Biosynthesis  PurR: transcription regulator associated with purine metabolism
  • PFAM:
    PRTase-like (CL0533) Pribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 103.3)
    HTH (CL0123) PuR_N; Bacterial purine repressor, N-terminal (PF09182; HMM-score: 96.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by PurR, TF important in Purine metabolism: in TIGR4

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018361
    • TAT(Tat/SPI): 0.000493
    • LIPO(Sec/SPII): 0.000692
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM92108 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDIVIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGYIYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVRRDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMISLLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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