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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_RS01590 [old locus tag: SP670_0317 ]
  • pan locus tag?: PNEUPAN000972000
  • symbol: SP670_RS01590
  • pan gene symbol?: potD_1
  • synonym:
  • product: extracellular solute-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_RS01590 [old locus tag: SP670_0317 ]
  • symbol: SP670_RS01590
  • product: extracellular solute-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 269928..270944
  • length: 1017
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014498 (269928..270944) NCBI
  • BioCyc: SP670_RS01590 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAAAGAAATGGATGTATTATGCTGCTTGTTCTTCTAATGAATCTGCCGATGACAGT
    TCATCTGATAAAGGAGACGGCGGTTCGCTAGTCGTTTATTCACCAAACTCAGAGGGCTTA
    ATTGGAGCAACTATTCCTGCCTTTGAAGAAAAATATGGTATCAAAGTAGAACTGATTCAA
    GCTGGTACTGGAGAACTTTTCAAAAAACTAGAGTCAGAAAAAGAAGTTCCTGTAGCTGAT
    GTTATCTTTGGTGGTTCTTATACACAATATACTACCCACGGAGAACTCTTTGAAAACTAT
    ACTTCAAAAGAAAATGATAATGTTATCAAAGAATATCAAAACACAACTGGCTACTCTACT
    CCTTATACACTAGATGGTAGTGTTTTAATCGTCAACCCTGATTTAACTAAAGGCATGAAC
    ATCGAAGGATATAACGATCTTTTCAAACCTGAACTAAAAGGAAAAATCGCAACTGCTGAC
    CCAGCAAACTCTTCTAGCGCCTTTGCTCAATTAACAAATATGCTACAAGCTCAAGGTGGT
    TACAAAGATGATAAGGCTTGGTCTTATGTAAAAGATCTTTTCACACTTATTGATGGTAAA
    ATCGGTTTAAGTTCATCTGGTGTCTATAAAGCAGTCGCTGATGGAGAAATGACTGTTGGT
    CTCTCTTATGAAGATCCAGCAATTAAACTCTTAAATGACGGAGCTAACATTAAGGTAGTC
    TATCCAAAAGAAGGAACCGTCTTCCTACCTGCTAGTGCTGCTATCGTTAAAAAATCTAAA
    AATATGGAAAATGCCAAGAAATTTATCGATTTTATTATCTCTCAAGAAGTACAAGATACA
    CTTGGTACAACCACTACTAACCGTCCTGTTCGTAAAAATGCTAAAACAAGCGAAAACATG
    AAACCAATTGACAAAATCAAAACACTCACTGAAGATTATGATTATGTCATCAAGAATAAA
    TCAGATATCGTTAAGAAATACAACGAAGTCTTTACAGATATCCAATCTAAACAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1017

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_RS01590 [old locus tag: SP670_0317 ]
  • symbol: SP670_RS01590
  • description: extracellular solute-binding protein
  • length: 338
  • theoretical pI: 4.8437
  • theoretical MW: 37155.5
  • GRAVY: -0.481953

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein (TIGR03261; HMM-score: 143.9)
    and 5 more
    2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein (TIGR03227; HMM-score: 90.6)
    Metabolism Transport and binding proteins Other ABC transporter periplasmic binding protein, thiB subfamily (TIGR01254; HMM-score: 62.1)
    Metabolism Transport and binding proteins Other thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein (TIGR01276; HMM-score: 23.7)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, periplasmic molybdate-binding protein (TIGR01256; HMM-score: 21.3)
    Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 14.1)
  • TheSEED: see SP670_0317
  • PFAM:
    PBP (CL0177) SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 96.1)
    SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 93.7)
    SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 92.4)
    and 2 more
    SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 62.8)
    Phosphonate-bd; ABC transporter, phosphonate, periplasmic substrate-binding protein (PF12974; HMM-score: 15.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0107
    • Cytoplasmic Membrane Score: 0.2215
    • Cell wall & surface Score: 0.0109
    • Extracellular Score: 0.7569
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.033413
    • TAT(Tat/SPI): 0.000309
    • LIPO(Sec/SPII): 0.011337
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000731177 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGATIPAFEEKYGIKVELIQAGTGELFKKLESEKEVPVADVIFGGSYTQYTTHGELFENYTSKENDNVIKEYQNTTGYSTPYTLDGSVLIVNPDLTKGMNIEGYNDLFKPELKGKIATADPANSSSAFAQLTNMLQAQGGYKDDKAWSYVKDLFTLIDGKIGLSSSGVYKAVADGEMTVGLSYEDPAIKLLNDGANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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