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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_RS08225 [old locus tag: SP670_1660 ]
  • pan locus tag?: PNEUPAN002959000
  • symbol: SP670_RS08225
  • pan gene symbol?: dnaD
  • synonym:
  • product: DnaD domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_RS08225 [old locus tag: SP670_1660 ]
  • symbol: SP670_RS08225
  • product: DnaD domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1550300..1550977
  • length: 678
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_014498 (1550300..1550977) NCBI
  • BioCyc: SP670_RS08225 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1405 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACATATTTAGACGCTTTTAAATCAGGTACCTTGGTTTTACCGAGTGCCCTGCTCTTG
    CATTTTAAGGAACTCTTTCCTTCTAGCGACGATTTTCTGGTTTGGCAATTTTTCTATTTG
    CAAAATACGACAGGCTTAGAAGAAATATCGCCAAGCCAGATTGCTGAAAGGATTGGCAAG
    GAAATTTCGGATGTCAACCAGTCCATTTCTAATCTGACGGAAAGGGGACTGCTCCAGTAT
    CGTACTATCGAATTAAATGGCGAAATTGAATTGCTCTTTGATGCTAGTTTGGCCTTGGAA
    CGTTTGGATGACCTGTTTGGAGCAGTTCATTCAAGTTCAGACCAGCTAACACCACAAAAC
    CAGCTCAAGGATTTGGTGGAAACCTTCCAGCAGGAGTTGGGACGATTGTTGACGCCTTTT
    GAGATTGAGGATTTGACCAAGACACTAAAGGAAGATGGAACCAGTGCTGACTTGATTAAG
    GAGGCTCTTCGTGAAGCTGTTTTGAACGGAAAACCAAACTGGAAGTACATTCAGGCGATT
    TTGAGAAACTGGCGCCATGAAGGAATCAAGAGTGTGGCTCAAATTGAGGCCAAGAGAGCA
    GAAAGAGAAGCAAGCAATCCTCAGTTGACACAGGTATCTGCAGATTTCATAAATGCCATG
    GATCTCTGGAAGGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    678

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_RS08225 [old locus tag: SP670_1660 ]
  • symbol: SP670_RS08225
  • description: DnaD domain-containing protein
  • length: 225
  • theoretical pI: 4.38444
  • theoretical MW: 25587.7
  • GRAVY: -0.306222

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaD domain protein (TIGR01446; HMM-score: 98)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions DnaD domain protein (TIGR01446; HMM-score: 98)
    and 1 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaD family protein (TIGR04548; HMM-score: 17.8)
  • TheSEED: see SP670_1660
  • PFAM:
    no clan defined DnaB_2; Replication initiation and membrane attachment (PF07261; HMM-score: 82.7)
    and 7 more
    HTH (CL0123) MarR_2; MarR family (PF12802; HMM-score: 18.1)
    Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 17.3)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 17.1)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 16.3)
    no clan defined CtsR_C; CtsR C-terminal dimerization domain (PF17727; HMM-score: 13.6)
    HTH (CL0123) TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 12.5)
    no clan defined VPS11_C; Vacuolar protein sorting protein 11 C terminal (PF12451; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010926
    • TAT(Tat/SPI): 0.001125
    • LIPO(Sec/SPII): 0.001372
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000221604 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTTGLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERLDDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIKEALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFINAMDLWKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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