PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 31-JAN-2014

⊟Summary

• organism: Streptococcus pneumoniae 70585
• locus tag: SP70585_2047 [new locus tag: SP70585_RS10170 ]
• pan locus tag^?: PNEUPAN003592000
• symbol: SP70585_2047
• pan gene symbol^?: yidC1
• synonym: yidC
• product: membrane protein OxaA 2

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SP70585_2047 [new locus tag: SP70585_RS10170 ]
• symbol: SP70585_2047
• product: membrane protein OxaA 2
• replicon: chromosome
• strand: +
• coordinates: 1884664..1885590
• length: 927
• essential: unknown

⊟Accession numbers

• Location: CP000918 (1884664..1885590) NCBI
• BioCyc: see SP70585_RS10170
• MicrobesOnline: 7477966 MicrobesOnline
• PneumoBrowse for strain D39V: SPV_1773 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  
  GTGAAATCTATTAAACGTTTTGCACTCTCAGCTATGGGAGTGGCTATGTTGCTTGTCTTG
  ACTGGCTGTGTCAATGTCGATAAAACCACAGGTCAGCCAACAGGATTTATTTGGAATACG
  ATCGGAGCGCCTATGGCTGAAGCCATCAAGTACTTCGCTACTGATAAAGGTCTAGGCTTT
  GGTGTCGCTATCATTATCGTAACCATTATCGTACGCTTGATTATCTTACCACTTGGTATC
  TACCAATCATGGAAGGCAACGCTTCACTCTGAAAAGATGAACGCTCTCAAGCATGTCCTT
  GAGCCACACCAAACACGTCTCAAAGAAGCAACTACTCAAGAAGAAAAACTCGAAGCCCAA
  CAAGCCCTCTTTGCCGCTCAAAAAGAGCACGGCATCAGCATGTTTGGTGGTGTAGGATGT
  TTCCCTATCCTCCTTCAAATGCCTTTCTTCTCTGCTATCTACTTTGCTGCCCAACATACT
  GAAGGGGTTGCTCAAGCAAGCTACCTAGGCATTCCTCTAGGTTCTCCAAGTATGATTTTG
  GTTGCCTGTGCTGGTGTCCTTTACTATCTTCAATCGCTCCTTTCACTTCACGGAGTAGAA
  GATGAAATGCAAAGAGAACAAATCAAGAAAATGATTTACATGAGCCCACTCATGATCGTC
  GTCTTCTCCCTCTTCTCACCAGCTAGTGTCACACTTTACTGGGTTGTCGGTGGTTTCATG
  ATGATTCTCCAACAGTTTATCGTCAACTATATCGTTCGTCCAAAACTTCGCAAAAAAGTC
  CGTGAAGAACTAGCCAAGAACCCACCAAAAGCAAGTGCTTTCTCTAAACCAAGTGGACGA
  AAAGACGTTACCCCTGAACAACCAACTGCTATCACAAGCAAGAAAAAACACAAAAATCGC
  AACGCTGGAAAACAACGTTCGAGATAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  927
  

⊟Protein

⊟General

• locus tag: SP70585_2047 [new locus tag: SP70585_RS10170 ]
• symbol: SP70585_2047
• description: membrane protein OxaA 2
• length: 308
• theoretical pI: 10.3912
• theoretical MW: 34105.2
• GRAVY: 0.146104

⊟Function

• TIGRFAM:
  Genetic information processing Protein fate Protein and peptide secretion and trafficking membrane protein insertase, YidC/Oxa1 family (TIGR03592; HMM-score: 132.7)
  and 1 more
  Genetic information processing Protein fate Protein and peptide secretion and trafficking preprotein translocase, SecY subunit (TIGR00967; HMM-score: 10.3)
• TheSEED  :
  • Inner membrane protein translocase component YidC, OxaA protein
• PFAM:
  Oxa1 (CL0376) 60KD_IMP; 60Kd inner membrane protein (PF02096; HMM-score: 114.1)
  and 6 more
  no clan defined DUF3611; Protein of unknown function (DUF3611) (PF12263; HMM-score: 15.8)
  Oxa1 (CL0376) EMC3_TMCO1; Integral membrane protein EMC3/TMCO1-like (PF01956; HMM-score: 14.6)
  no clan defined DUF2418; Protein of unknown function (DUF2418) (PF10332; HMM-score: 12.5)
  Ninjurin; Ninjurin (PF04923; HMM-score: 11.6)
  SspP; Small acid-soluble spore protein P family (PF08179; HMM-score: 9.9)
  BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 6.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 5
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9983
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0016
• SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
  • SP(Sec/SPI): 0.000921
  • TAT(Tat/SPI): 0.000107
  • LIPO(Sec/SPII): 0.998471
  • Cleavage Site: CS pos: 22-23. LTG-CV. Pr: 0.9992
• predicted transmembrane helices (TMHMM): 6

⊟Accession numbers

• GI:
• RefSeq: ACO17020 NCBI
• UniProt: C1CA20 UniProt

⊟Protein sequence

• MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAPMAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEPHQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHTEGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLMIVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSKPSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SP70585_2046 > SP70585_2047

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1773 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications