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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
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serotype 1
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serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS04140 [old locus tag: SP70585_0840 ]
  • pan locus tag?: PNEUPAN001746000
  • symbol: SP70585_RS04140
  • pan gene symbol?: ptsP
  • synonym:
  • product: putative PEP-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS04140 [old locus tag: SP70585_0840 ]
  • symbol: SP70585_RS04140
  • product: putative PEP-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 765873..766526
  • length: 654
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGCTATGAAAAATCAACTTGCCCTTAGTGGCGAAAAAATTCTTGAAAAAATTTATCCT
    CTGTTTGGCTATAGAGGAACTAGGCGTTTACTGGCGTGTTTGGATGAATTTCAGGCTGAA
    GCACATGTCATTACAGAAGTTTATCAAACCAACCCCAATCTATCTGTTATCTTTCCTTTT
    GTCAATGATGCCGACCAATTAAAACAAGCTATTACAGTATTGCGTCAGTATGGCTTTACT
    GGGAAAGTCGGAACGATGATTGAATTACCGTCAGCGTATTTTGACTTATCTAGTATACTG
    GAAACGGGCATTTCAAAGATTGTAGTTGGAATGAATGATTTGACTTCCTTTGTTTTTGCG
    ACTATGAGAAACAGTCAATGGCATGATATGGAAAGTCCAATAATGTTAGATATGCTAAGA
    GATATGCAGGATAAAGCAAGAAAGAACAAGATTAATTTTGCTGTAGCAGGCTATCTGAAT
    ACTTCTTTCATACAAAAAATGAATCAGTTGGGTATCAAGTGCATTATCCACTACAGTTCT
    ATTCCAGAGATTTTTGATTTAGAGATTGACCATCCAGATCATCTTAAACACATAAAAGAA
    GAAAGTAAAAAATTACAAAGGAGTACCCATGACACCGCAAGAAATGTGGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    654

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS04140 [old locus tag: SP70585_0840 ]
  • symbol: SP70585_RS04140
  • description: putative PEP-binding protein
  • length: 217
  • theoretical pI: 6.88656
  • theoretical MW: 24834.5
  • GRAVY: -0.205069

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Glycolysis/gluconeogenesis phosphoenolpyruvate synthase (TIGR01418; EC 2.7.9.2; HMM-score: 56.8)
    and 3 more
    phosphoenolpyruvate-protein phosphotransferase (TIGR01417; EC 2.7.3.9; HMM-score: 39)
    Metabolism Energy metabolism Other pyruvate, phosphate dikinase (TIGR01828; EC 2.7.9.1; HMM-score: 16.4)
    VWFA-related Acidobacterial domain (TIGR03436; HMM-score: 12.7)
  • TheSEED: see SP70585_0840
  • PFAM:
    PK_TIM (CL0151) PEP-utilizers_C; PEP-utilising enzyme, PEP-binding domain (PF02896; HMM-score: 58.7)
    and 5 more
    no clan defined pP_pnuc_1; Predicted pPIWI-associating nuclease (PF18165; HMM-score: 15.5)
    RNase_H (CL0219) DDE_Tnp_1; Transposase DDE domain (PF01609; HMM-score: 14)
    TPR (CL0020) EAD11; Effector-associated domain 11 (PF19964; HMM-score: 13.4)
    HTH (CL0123) DpnI_C; Dam-replacing HTH domain (PF17726; HMM-score: 13.1)
    no clan defined DUF4023; Protein of unknown function (DUF4023) (PF13215; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9872
    • Cytoplasmic Membrane Score: 0.0038
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0089
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005184
    • TAT(Tat/SPI): 0.000439
    • LIPO(Sec/SPII): 0.000904
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAMKNQLALSGEKILEKIYPLFGYRGTRRLLACLDEFQAEAHVITEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIELPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKARKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKKLQRSTHDTARNVE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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