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serotype 4
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D39V
serotype 2
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EF3030
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70585
serotype 5
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A66
serotype 3
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serotype 19A
Hu17
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INV200
serotype 14
JJA
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serotype 19F
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serotype 1
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serotype 2
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serotype 3
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SPN032672
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serotype 3
SPN034183
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SPN994038
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SPN994039
serotype 3
SPNA45
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ST556
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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS04780 [old locus tag: SP70585_0962 ]
  • pan locus tag?: PNEUPAN001904000
  • symbol: SP70585_RS04780
  • pan gene symbol?: yidA_1
  • synonym:
  • product: HAD family hydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS04780 [old locus tag: SP70585_0962 ]
  • symbol: SP70585_RS04780
  • product: HAD family hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 891039..891848
  • length: 810
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGATTAAACTACTAGCCTTGGATATGGACGGCACCCTCCTCAATGAAGCCAAGGAAATC
    CCACAAGCTCACATTACTGCTATTCACAAAGCCATTGAAAAAGGTGTCAAACTGGTTCTC
    TGTACGGGTCGCCCCCTTTTCGGTGTCCTCCCCTACTACAAAAAACTGGAGCTTGACCTC
    CAGAACGAATATATTATTGTTAACAACGGTTGTTCAACTCACCAGACTAGCGACTGGGGC
    TTGGTTGACTGGCAAGAACTGAGTCCAGCTGACATCGAATACCTCTATGACCTTGCTGAA
    AAGAGTGATGTTCAGTTGACACTTTTTGACGAGTCACATTATTTTGTTCTCGGTGGCAAA
    CCCAATCAAGTTATTGAAAATGATGCTAAACTAGTATTTTCAGACCTGACTGAAATTTCT
    CTTGAAGAAGCGACTAGTGGAAAGTTCCGGATGTTCCAAGGTATGTTTTTAGGAACAAAA
    GAACAAACAGACGATTTTGAGCAGCGTTTTGCTGAAGAGCTTTGCCAACGATTCAGTGGA
    GTTCGTTCGCAGCCTGTCATTTATGAAGCAATGCCGCTTGGAACGACAAAGGCTACTGCT
    CTTTCACGACTAGCTGAGATTTTGAAGATTGATTCCTCAGAGATTATGGCCATGGGCGAT
    GCTAATAACGATATCGAAATGCTCCAGTTTGCAGGGCTTGGGATTGCAATGGGAAATGCC
    AGCGATTATGTCAAATCTCTTGCGGATGCCGTTACATCAAGCAACGAAGAAGACGGCGTT
    GCGCGTGCTATTGAGAAATATATTCTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    810

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS04780 [old locus tag: SP70585_0962 ]
  • symbol: SP70585_RS04780
  • description: HAD family hydrolase
  • length: 269
  • theoretical pI: 4.24891
  • theoretical MW: 29907.8
  • GRAVY: -0.116357

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.3.-?  ExPASy
  • TIGRFAM:
    Unknown function Enzymes of unknown specificity Cof-like hydrolase (TIGR00099; HMM-score: 200.3)
    and 27 more
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIB (TIGR01484; HMM-score: 85.6)
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 85.2)
    sucrose-phosphate phosphatase subfamily (TIGR01482; EC 3.1.3.-; HMM-score: 74)
    mannosyl-3-phosphoglycerate phosphatase family (TIGR01486; EC 3.1.3.-; HMM-score: 49.8)
    Unknown function General mannosyl-3-phosphoglycerate phosphatase homolog (TIGR02463; EC 3.1.3.-; HMM-score: 40.5)
    mannosyl-3-phosphoglycerate phosphatase (TIGR02461; EC 3.1.3.70; HMM-score: 37.5)
    Metabolism Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 33.1)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family (TIGR01670; EC 3.1.3.45; HMM-score: 29.3)
    phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 26.9)
    Unknown function Enzymes of unknown specificity HAD phosphoserine phosphatase-like hydrolase, family IB (TIGR01488; HMM-score: 26.8)
    heavy metal translocating P-type ATPase (TIGR01525; EC 3.6.3.-; HMM-score: 25.3)
    Metabolism Energy metabolism Anaerobic phenylphosphate carboxylase, delta subunit (TIGR02726; HMM-score: 25.1)
    sucrose-phosphate synthase, sucrose phosphatase-like domain (TIGR02471; HMM-score: 23.8)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cadmium-translocating P-type ATPase (TIGR01512; EC 3.6.3.3; HMM-score: 23)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IB (TIGR01490; HMM-score: 22.7)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIIA (TIGR01662; HMM-score: 22.7)
    sucrose phosphatase (TIGR01485; EC 3.1.3.24; HMM-score: 22.1)
    Cellular processes Cellular processes Detoxification copper-translocating P-type ATPase (TIGR01511; EC 3.6.3.4; HMM-score: 19.3)
    Metabolism Transport and binding proteins Cations and iron carrying compounds copper-translocating P-type ATPase (TIGR01511; EC 3.6.3.4; HMM-score: 19.3)
    HAD ATPase, P-type, family IC (TIGR01494; EC 3.6.3.-; HMM-score: 16.6)
    Metabolism Energy metabolism Sugars phosphoglycolate phosphatase, bacterial (TIGR01449; EC 3.1.3.18; HMM-score: 14.2)
    Metabolism Transport and binding proteins Cations and iron carrying compounds calcium-translocating P-type ATPase, SERCA-type (TIGR01116; EC 3.6.3.8; HMM-score: 13.3)
    potassium/sodium efflux P-type ATPase, fungal-type (TIGR01523; EC 3.6.3.-; HMM-score: 13.2)
    plasma-membrane proton-efflux P-type ATPase (TIGR01647; EC 3.6.3.6; HMM-score: 13)
    phosphonatase-like hydrolase (TIGR03351; HMM-score: 12.8)
    calcium-transporting P-type ATPase, PMR1-type (TIGR01522; EC 3.6.3.8; HMM-score: 12.5)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIA (TIGR01460; HMM-score: 11.9)
  • TheSEED: see SP70585_0962
  • PFAM:
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 228.8)
    and 5 more
    S6PP; Sucrose-6F-phosphate phosphohydrolase (PF05116; HMM-score: 50.8)
    Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 30.4)
    HAD; haloacid dehalogenase-like hydrolase (PF12710; HMM-score: 22.6)
    HAD_2; haloacid dehalogenase-like hydrolase (PF13419; HMM-score: 20)
    Hydrolase_6; haloacid dehalogenase-like hydrolase (PF13344; HMM-score: 15.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9984
    • Cytoplasmic Membrane Score: 0.0006
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0009
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003872
    • TAT(Tat/SPI): 0.000174
    • LIPO(Sec/SPII): 0.00073
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGRPLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKSDVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTKEQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAMGDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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