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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 15-DEC-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae 70585
- locus tag: SP70585_RS05295 [old locus tag: SP70585_1062 ]
- pan locus tag?: PNEUPAN002046000
- symbol: SP70585_RS05295
- pan gene symbol?: —
- synonym:
- product: GNAT family N-acetyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP70585_RS05295 [old locus tag: SP70585_1062 ]
- symbol: SP70585_RS05295
- product: GNAT family N-acetyltransferase
- replicon: chromosome
- strand: +
- coordinates: 977350..977781
- length: 432
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012468 (977350..977781) NCBI
- BioCyc: SP70585_RS05295 BioCyc
- MicrobesOnline: see SP70585_1062
- PneumoBrowse for strain D39V: SPV_0909 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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421ATGCTAAGAGATTTGCAAGAAACAGATGTGAAAGCGATATGTGACATCAACCAAGAGGCT
TTGGGTTATACTTTTAGTCCAGAGGAAACGGCTAGCCAACTAGCTAGACTGTCTCAGGAT
TCCCATCATTTCCTACTTGGCTATGAGGATGCAGCTAATCATGTCTTACTTGGATATGTC
CACGCTGAAGTTTACGAATCACTCTATTCCAAAGCAGGATTTAATATCTTAGCTTTAGCA
GTTTCACCTCAAGCGCAAGGTCAAGGTATTGGTAAAAGTTTACTACAAGGGTTGGAAGAA
GAAGCAAAAAGATGTGGTTATGGGTTTATCCGCTTAAATTCTGCCAATCATCGTCTGGGT
GCTCATGCATTTTATGAAAAAGTTGGCTATACTTGTGATAAAATGCAGAAACGGTTTATT
CGCATCTGTTAG60
120
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432
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP70585_RS05295 [old locus tag: SP70585_1062 ]
- symbol: SP70585_RS05295
- description: GNAT family N-acetyltransferase
- length: 143
- theoretical pI: 6.50267
- theoretical MW: 15973
- GRAVY: -0.251748
⊟Function[edit | edit source]
- reaction: EC 2.3.-.-? ExPASy
- TIGRFAM: Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 49.2)and 5 moreGNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 25.9)Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 18.9)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides TDP-D-fucosamine acetyltransferase (TIGR02382; HMM-score: 13.2)Amino acid biosynthesis Glutamate family amino-acid N-acetyltransferase (TIGR01890; EC 2.3.1.1; HMM-score: 13)putative beta-lysine N-acetyltransferase (TIGR03827; EC 2.3.1.-; HMM-score: 12.8)
- TheSEED: see SP70585_1062
- PFAM: Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 51.3)Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 51)Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 46.7)and 4 moreAcetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 21.4)Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 20)FR47; FR47-like protein (PF08445; HMM-score: 19.6)Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 14.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9952
- Cytoplasmic Membrane Score: 0.0002
- Cell wall & surface Score: 0.0002
- Extracellular Score: 0.0044
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003711
- TAT(Tat/SPI): 0.000851
- LIPO(Sec/SPII): 0.000623
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000942934 NCBI
- UniProt: see SP70585_1062
⊟Protein sequence[edit | edit source]
- MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHFLLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEAKRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SP70585_RS05270 > SP70585_RS05275 > prfA > prmC > SP70585_RS05290 > SP70585_RS05295 > glyA > SP70585_RS05305 > pmp23 > SP70585_RS05315 > rlmD
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0909 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]