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serotype 4
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serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS06235 [old locus tag: SP70585_1252 ]
  • pan locus tag?: PNEUPAN002466000
  • symbol: recN
  • pan gene symbol?: recN
  • synonym:
  • product: DNA repair protein RecN

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS06235 [old locus tag: SP70585_1252 ]
  • symbol: recN
  • product: DNA repair protein RecN
  • replicon: chromosome
  • strand: -
  • coordinates: 1162515..1164182
  • length: 1668
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGTTACTTGAAATTTCGATAAAAAACTTTGCCATTATTGAGGCTATTTCCCTCAATTTT
    GAAAAGGGGATGACTGTCCTGACTGGTGAAACGGGTGCAGGGAAGTCGATTATCATTGAT
    GCCATGAATATGATGTTGGGAGCTCGTGCGACGACAGATGTTATTCGTCATGGTGCACCA
    AAGGCAGAGATTGAGGGGCTTTTCTCAGTTGAGAATAGTCGTCTTTTACAGGAAATTTTT
    GATGAGCAAGGTTTAGAATTAGGTGATGAAATTATCATCCGTCGGGAAATCTTGCAAAAT
    GGTCGTAGTATCAGCCGTGTAAATGGTCAGATGGTTAATCTGTCTGTTTTGCGAACTATT
    GGGCAACATCTTGTAGATATTCATGGTCAGCATGACCATGAGGAGTTAATGCGTCCCCAA
    CTGCATATCCAGATGTTGGATGAATTTGGTGATGCCGCTTTTTGGGACTTGAAAGAAACC
    TATCAAACGAGTTTTGATGCCTATCGGAAAATGCGCAAGCAGGTTCTGGAAGTCAAGAAA
    AACCAACAGGAACACAAGGCACGTATCGAAATGTTGGAATTTCAAATGGCAGAGATTGAG
    GCAGCAAACTTGCAGGCTGGAGAAGACTTGGATCTCAATCAAGAGCGAGATAAACTCCTC
    AACCACAAAAATATTGCGGATACACTGACCAATGCCTACAGTATGTTGGACAATGAAGAT
    TTTTCAAGTCTGGCCAATGTTCGTTCAGCCATGAATGACATGGAAAGTGTCGAAGAGTAT
    GACCCTGAATACCGTGAAATTTCAAGCTCTCTGTCTGAGACCTACTATGTTTTAGAAGAC
    ATTAGCAAACGTTTGGAAGCTATCATTGAGGACCTTGATTTTGATGGCAATCGCCTCATG
    CAGGTTGAGAATCGTTTGGACCTCCTTCATACTATTACTCGTAAGTATGGTGGGACTGTT
    GATGATGTTTTGCTTTATTTTGCCAAGATTACGGAAGAATACAATCTCTTGACAGGCAAT
    AATCTTTCGTCTGAGGACATGGAAGCAGAGCTTAAGAAGTTGGAAGTCAATCTTGTCAAT
    TTGGCAGGTCAACTTGCTTCTGCTCGTCATAATTTGGCTCAGCAACTCGAAGCTGAGATT
    AAACAAGAACTGCAAGATCTTTATATGGAAAAAGCCCAGTTTCAGGTTCGTTTTAGTAAG
    GGAAAATTCAGTCGTGAGGGAAATAAAATGGTTGAGTTTTATATTTCAACCAACCCTGGA
    GAAGACTTTAAACCCTTGGTTAAGGTTGCTTCTGGAGGGGAATTATCTCGTCTCATGTTA
    GCCATTAAGTCTGCCTTTTCACGTAAAGAAGGCAAGACTAGCATTGTCTTTGATGAGGTG
    GATACGGGAGTTTCAGGTCGTGTTGCTCAAGCTATTGCTCAGAAAATTCATAAAATTGGT
    CAGCATGGTCAGGTTTTGGCTATCTCCCATTTGCCACAAGTAATTGCGATTGCAGATTAT
    CAATTCTTTATTGAGAAGATTAGTAATGACCATTCAACGGTTTCGACTGTTCGTCTCTTG
    ACGGTCGAAGAGCGAGTGGAGGAAGTTGCCAAGATGTTGGCAGGTGATGATGTGACAGAA
    GCAGCCCTGACGCAAGCCAGAGAATTGTTGAGAAACAGGGAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1668

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS06235 [old locus tag: SP70585_1252 ]
  • symbol: RecN
  • description: DNA repair protein RecN
  • length: 555
  • theoretical pI: 4.67981
  • theoretical MW: 62864.9
  • GRAVY: -0.346126

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair protein RecN (TIGR00634; HMM-score: 552.4)
    and 10 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA replication and repair protein RecF (TIGR00611; HMM-score: 36.4)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 36.4)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 36.4)
    thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 19.8)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 18.7)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 17.4)
    Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 15.9)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 15.9)
    Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 15.4)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 15.2)
  • TheSEED: see SP70585_1252
  • PFAM:
    P-loop_NTPase (CL0023) SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 70)
    and 16 more
    AAA_23; AAA domain (PF13476; HMM-score: 44.2)
    AAA_15; AAA ATPase domain (PF13175; HMM-score: 37)
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 28)
    AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 25.9)
    AAA_22; AAA domain (PF13401; HMM-score: 24.1)
    RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 17.3)
    NTPase_P4; ATPase P4 of dsRNA bacteriophage phi-12 (PF11602; HMM-score: 15.6)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 14)
    ABC_tran; ABC transporter (PF00005; HMM-score: 13.2)
    no clan defined Lipin_N; lipin, N-terminal conserved region (PF04571; HMM-score: 13.1)
    P-loop_NTPase (CL0023) AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 12.9)
    no clan defined Holin_BhlA; BhlA holin family (PF10960; HMM-score: 12.3)
    HEF_HK; HEF_HK domain (PF19191; HMM-score: 11.2)
    FlxA; FlxA-like protein (PF14282; HMM-score: 10.5)
    P-loop_NTPase (CL0023) AAA_30; AAA domain (PF13604; HMM-score: 8.7)
    H2TH (CL0303) NFACT_N; NFACT N-terminal and middle domains (PF05833; HMM-score: 6.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008509
    • TAT(Tat/SPI): 0.001489
    • LIPO(Sec/SPII): 0.00084
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMMLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDKLLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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