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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS06450 [old locus tag: SP70585_1296 ]
  • pan locus tag?: PNEUPAN002484000
  • symbol: SP70585_RS06450
  • pan gene symbol?: —
  • synonym:
  • product: asparagine synthase-related protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS06450 [old locus tag: SP70585_1296 ]
  • symbol: SP70585_RS06450
  • product: asparagine synthase-related protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1199135..1200859
  • length: 1725
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012468 (1199135..1200859) NCBI
  • BioCyc: SP70585_RS06450 BioCyc
  • MicrobesOnline: see SP70585_1296
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGGTAAATAAGTATTTTTTTGAAAAATATTCTGATAAAAAAATAGTATTCCTTACTAAA
    AATTTATATAGAACCGTTTCTGGAGAGAATAAAAAAATCTATTGTTTAGAAGATTATGTC
    GAAGGAGTATGCTCAATTATAGAACAAAATGATATTAGTAGTTTTGAAGAAATAATATTA
    GCACTTCAAGATTATGTTACAAATGGTTTAATTATTGTTGAAATGACTGAAAGAACATAT
    ATTATTTCACCTTATTTAGATTCAAGACTGTCTTGGTTTGAGAATAATAAGAATATAATT
    TTTAGTGATTCATCTGTAGAAATTGCAAAATATTTGAATTTAAAACTCTCTACGAAGCGT
    TTAGCAAGTCAATTTATTTTTGGACTTCCATATTATCCATTTCAAACAATTAGCCTCTGG
    GAAGAGCTAGTGAATATAAGACCTTTAAACTATTTAGAAATATCTGAAAAAGGTTGTTTA
    GAAAAAAGAGTTCCGAGTTATGAAGTAGACACAAAAGATTTTAATAAACTAATAATAAAA
    ATAAAAGAGGAGTTTTTAAATAGCATTAATCATGATTTGAATATGAGAAATGAAGTGTCG
    AGTGATGTATCAGGAGGTGTTGATTCTGCAACTATTGCTTTTACATTGAATAAACTGATA
    CCTGACTTCTCTATTTTGCATGCTGAATCAAGTACCACTGCTAATAGTGATACTAAATGG
    GCGACATTTATTGCTAAAAGTCTTGGTAGGGAGTTGAAAAAGTTTGACTCAATAGAAATA
    ACAGAAAAAAGATTTGCGATAGATGAAAAATATATCAATGATATTATGCCAAGTTCTCCG
    TTATTGTGGGCGGATTCAGAAGGATATTTGAAATCAGTGATTGGTTACCAGAAAGGTAGA
    AAACAACCGACTCACTTTCTAGGTATTGGTGGTGATGAATTATTTACACCGATGCCGTCT
    AATTCCTGGAATATTGTTCGTCAGGAAAATTTAGGTGGACTACTTTATGCTCTGAAATAT
    AGTTTAATAATGAGAAGACCATTTTTTAGTTGCCTATTGGATTTGTTAGATAATAGAGGA
    TATTCGGAAACTGTGATCAAAAATTTAGAAATTGTTTTCAACGAATCTTCTGCACCTATC
    AAGAGAGAACTGGGATGGGTGGATGGTTTACAAGTACCAGATTGGCTCAGTGAAAAATCC
    AAACAAGAATCGCAAATTTTTTTAAACTCGTTATTATTTTCCAATTCTGAGCCAATAATA
    TCTGATAGGACAGCCTTCCAAATGATTCAATCCTTAATATTTCAAAAATCAGTATTGCGA
    CAAATTCAATTAACCACTAATTCCATTTATTGGGCAACTCCATTTTTACATAAAAAATTA
    ATAGAAATTTGTCTTCAAATTCCAGCAAAATATAAAGTTAGTTCAAAACTAACAAAACCG
    ATATTGCAAAAAGCATTGAAGGGAATCGTACCAATTGAGGTTTTTAACAGGGGTTTCAAA
    GGGGATTATTCAGATGCCTTATATAGTGGATATAGAGAAGCAGTTCGTAAAAACTTCCAC
    AATTTAGAACAGTTTGAATTGGTTAAAATGGGTATTATTGATGTTGAGAAGTTAAAATTA
    GAGATGTCATTACCCGCGGGAAATCCGAGTAAAATTGATTATTTTGAAAAGTTATGTTCG
    GTAGAACGTTGGATACGGCAGATCAAATTATATATGAAGAACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1725

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS06450 [old locus tag: SP70585_1296 ]
  • symbol: SP70585_RS06450
  • description: asparagine synthase-related protein
  • length: 574
  • theoretical pI: 7.77945
  • theoretical MW: 66305
  • GRAVY: -0.202962

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family asparagine synthase (glutamine-hydrolyzing) (TIGR01536; EC 6.3.5.4; HMM-score: 66)
    and 3 more
    asparagine synthase family amidotransferase (TIGR03104; HMM-score: 23.2)
    exosortase A system-associated amidotransferase 1 (TIGR03108; HMM-score: 22.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides NAD+ synthetase (TIGR00552; EC 6.3.1.5; HMM-score: 14.2)
  • TheSEED: see SP70585_1296
  • PFAM:
    HUP (CL0039) Asn_synthase; Asparagine synthase (PF00733; HMM-score: 85.4)
    and 1 more
    NAD_synthase; NAD synthase (PF02540; HMM-score: 15.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0977
    • Cytoplasmic Membrane Score: 0.8625
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0397
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017025
    • TAT(Tat/SPI): 0.000122
    • LIPO(Sec/SPII): 0.001973
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVNKYFFEKYSDKKIVFLTKNLYRTVSGENKKIYCLEDYVEGVCSIIEQNDISSFEEIILALQDYVTNGLIIVEMTERTYIISPYLDSRLSWFENNKNIIFSDSSVEIAKYLNLKLSTKRLASQFIFGLPYYPFQTISLWEELVNIRPLNYLEISEKGCLEKRVPSYEVDTKDFNKLIIKIKEEFLNSINHDLNMRNEVSSDVSGGVDSATIAFTLNKLIPDFSILHAESSTTANSDTKWATFIAKSLGRELKKFDSIEITEKRFAIDEKYINDIMPSSPLLWADSEGYLKSVIGYQKGRKQPTHFLGIGGDELFTPMPSNSWNIVRQENLGGLLYALKYSLIMRRPFFSCLLDLLDNRGYSETVIKNLEIVFNESSAPIKRELGWVDGLQVPDWLSEKSKQESQIFLNSLLFSNSEPIISDRTAFQMIQSLIFQKSVLRQIQLTTNSIYWATPFLHKKLIEICLQIPAKYKVSSKLTKPILQKALKGIVPIEVFNRGFKGDYSDALYSGYREAVRKNFHNLEQFELVKMGIIDVEKLKLEMSLPAGNPSKIDYFEKLCSVERWIRQIKLYMKN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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