From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS11145 [old locus tag: SP70585_2243 ]
  • pan locus tag?: PNEUPAN003688000
  • symbol: SP70585_RS11145
  • pan gene symbol?: —
  • synonym:
  • product: MFS transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS11145 [old locus tag: SP70585_2243 ]
  • symbol: SP70585_RS11145
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 2053480..2055033
  • length: 1554
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012468 (2053480..2055033) NCBI
  • BioCyc: SP70585_RS11145 BioCyc
  • MicrobesOnline: see SP70585_2243
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGGAAAAACATGTTGAGCAACGTGTCGAAGACGTTACTTATAACAAAGCGAAGTTATGG
    CAAATCATCTTATTTGCGATGAATAATTCGTCGACGAATATTTACTTGGTTGCCTTTACT
    TTTGTGACTTATTTATCGACGGGTGTGCTTGGTCTGGCAGCGCTGTTTGTTAGCCAACTG
    ATGGGCTATATTCGTATCTTTGATGGTTTCATTGATCCAACAATTGGTGTTATTATTGAT
    AAAACAGATACTAAGTTTGGTAAATATCGTCCTATCTTGGTTTTGGGGAATATCATTACG
    GCTAGTTCCCTTTTCATGATGTTGGGCTTAAGTGGAGTTAGTGAGAATCTCCGTCTTCCC
    TTGTTTATACTTGTTTTGATTATCCATAAAATTGGTTATTCATTGCAACAGACTATTACG
    AAAGCGGGACAGGTTGCTCTTACCAATGATCCGAAACAACGTCCAATCTTCAATATTGTT
    GACGGTATTGCAACAACAGTATTGATGACTGGTAGTCAGGTTGTTGTATCAGGAACATTG
    GTTCCTAAACATGGTGGCTTCACACCAAGTTTCTTCCAAGAATTGTTCCTTGGTGTTGTG
    ATTATTTCAGCTATTCTGGGTATCCTTGCTATTATCGGTATTTGGGAAAAAGACAATAAG
    AAATACTTTGGTCTTGGCGAAAAAACGCAAGAAACTAAGTTGAAAGACTACTGGAAAGTT
    ATCAAAGGAAATAAACCTTTGCAGGTACTTTCAATCTCTGCAGCCTTTGTAAAATTTGTT
    GCTCAGTTGTTCGGTGATTCAGTTATCGGGGTTATGCTTTATGGTATTATCTTCGGTGAC
    TATGCTCTTTCTGGAAAAATGTCAATGCTCTTGATTTTGCCTGGTATCCTCGTAACAGTT
    GGTGCGGCACAGTTGGCTCGTCGTAAAGGTTTACGCTTTGCCTATATTACAGCGCTTCAG
    TTGGGTATTGCTGGTCTTGTTGCCTTGGCAGCGATGCTGTTTTCAGCAAAACCTGGTATG
    TTGGATTTAACAAATTGGAATCTCTACACAATCGGTTTCTTTGTTGTTTATATCATTGCA
    CGTTATGCATCTGGCGCTCCATCCGGTTTGGTATTGACAATGGGTGCAGATATTACAGAC
    TATGAAACATCAGTATCTGGTCGTTACTTGTCAGGTATGATTGGTACTATCTTCTCATTG
    ACAGACTCAATTGCGTCTTCATTTGCTCCAATGGTTGTTGGTTTTGTGTTAGCAGGTATT
    GGATTTGGTAAAGAATATCCAACTGTTGAAACAGCTTTCTCAACTGATTTGAGAATGGCA
    CTAATTGTCTTGTTAACAGTAATTCCAGCAGCGGTATTGAGCGTATCCTTGTTCTTGATG
    AAATTCTACAAACTAGACCGTGAAGAAATGGCTCGTATTCAAGAGAAAATCCATGTCATG
    AAAGCGGCAAAAGATGAAGAACGAGTGCGTGCTATTGCGAAAAATGTTCCACTATCTGAT
    ATGGACTACGTTGATGTAACTCAGTATAAGGTTGAACAATACGAAGATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1554

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS11145 [old locus tag: SP70585_2243 ]
  • symbol: SP70585_RS11145
  • description: MFS transporter
  • length: 517
  • theoretical pI: 9.5307
  • theoretical MW: 56718.7
  • GRAVY: 0.526692

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids sugar (Glycoside-Pentoside-Hexuronide) transporter (TIGR00792; HMM-score: 122.9)
  • TheSEED: see SP70585_2243
  • PFAM:
    MFS (CL0015) MFS_2; MFS/sugar transport protein (PF13347; HMM-score: 122.5)
    and 4 more
    MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 34.3)
    no clan defined Casc1_C; Cancer susceptibility candidate 1 C-terminal (PF12366; HMM-score: 11.8)
    MLANA; Protein melan-A (PF14991; HMM-score: 11.7)
    CrgA; Cell division protein CrgA (PF06781; HMM-score: 6.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003691
    • TAT(Tat/SPI): 0.000126
    • LIPO(Sec/SPII): 0.006928
  • predicted transmembrane helices (TMHMM): 11

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEKHVEQRVEDVTYNKAKLWQIILFAMNNSSTNIYLVAFTFVTYLSTGVLGLAALFVSQLMGYIRIFDGFIDPTIGVIIDKTDTKFGKYRPILVLGNIITASSLFMMLGLSGVSENLRLPLFILVLIIHKIGYSLQQTITKAGQVALTNDPKQRPIFNIVDGIATTVLMTGSQVVVSGTLVPKHGGFTPSFFQELFLGVVIISAILGILAIIGIWEKDNKKYFGLGEKTQETKLKDYWKVIKGNKPLQVLSISAAFVKFVAQLFGDSVIGVMLYGIIFGDYALSGKMSMLLILPGILVTVGAAQLARRKGLRFAYITALQLGIAGLVALAAMLFSAKPGMLDLTNWNLYTIGFFVVYIIARYASGAPSGLVLTMGADITDYETSVSGRYLSGMIGTIFSLTDSIASSFAPMVVGFVLAGIGFGKEYPTVETAFSTDLRMALIVLLTVIPAAVLSVSLFLMKFYKLDREEMARIQEKIHVMKAAKDEERVRAIAKNVPLSDMDYVDVTQYKVEQYEDK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP70585_RS11145&oldid=29127"