From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_0130 [new locus tag: SPAP_RS00650 ]
  • pan locus tag?: PNEUPAN000717000
  • symbol: SPAP_0130
  • pan gene symbol?: tnp (pseudogene)
  • synonym:
  • product: Transposase-like protein, IS630

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_0130 [new locus tag: SPAP_RS00650 ]
  • symbol: SPAP_0130
  • product: Transposase-like protein, IS630
  • replicon: chromosome
  • strand: +
  • coordinates: 125209..125367
  • length: 159
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    ATGGAATATTCAATAGATTTTCGTAAAAAAGTTCTCTCTTATTGTGAGCGAACAGGTAGT
    ATAACAGAAGCATCACACGTTTTCCAAATCTCACGTAATACCATTTATGGCTGGTTAAAG
    CTAAAAGAGAAAACAGGAGAGCTAAACCACCAAGTATAG
    60
    120
    159

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPAP_0130 [new locus tag: SPAP_RS00650 ]
  • symbol: SPAP_0130
  • description: Transposase-like protein, IS630
  • length: 52
  • theoretical pI: 9.14618
  • theoretical MW: 6135.97
  • GRAVY: -0.569231

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Mobile element protein
  • PFAM:
    HTH (CL0123) HTH_Tnp_IS630; Transposase (PF01710; HMM-score: 46.9)
    and 12 more
    HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 33.5)
    HTH_29; Winged helix-turn helix (PF13551; HMM-score: 21.9)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 17.8)
    HTH_17; Helix-turn-helix domain (PF12728; HMM-score: 17.5)
    HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 15.1)
    HTH_Tnp_1_2; Helix-turn-helix of insertion element transposase (PF13022; HMM-score: 14.3)
    HTH_22; HTH domain (PF13309; HMM-score: 13.9)
    no clan defined DUF658; Protein of unknown function (DUF658) (PF04936; HMM-score: 13.3)
    HTH (CL0123) HTH_30; PucR C-terminal helix-turn-helix domain (PF13556; HMM-score: 13)
    CENP-B_N; CENP-B N-terminal DNA-binding domain (PF04218; HMM-score: 12.6)
    HTH_psq; helix-turn-helix, Psq domain (PF05225; HMM-score: 12.1)
    no clan defined CCDC106; Coiled-coil domain-containing protein 106 (PF15794; HMM-score: 12)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9794
    • Cytoplasmic Membrane Score: 0.0006
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.0192
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02119
    • TAT(Tat/SPI): 0.001365
    • LIPO(Sec/SPII): 0.007082
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM83724 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MEYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEKTGELNHQV

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]