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serotype 4
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D39V
serotype 2
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serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
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A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
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HU-OH
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Hu15
serotype 19A
Hu17
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INV104
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INV200
serotype 14
JJA
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MDRSPN001
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NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
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SP49
serotype 19A
SPN032672
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SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
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ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_0576 [new locus tag: SPAP_RS02860 ]
  • pan locus tag?: PNEUPAN001480000
  • symbol: SPAP_0576
  • pan gene symbol?: higA
  • synonym:
  • product: Predicted transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_0576 [new locus tag: SPAP_RS02860 ]
  • symbol: SPAP_0576
  • product: Predicted transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 541227..541424
  • length: 198
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGAGCGAGTTGATTGAGGCTAGGTATGAACAAGGAATCAGTCAGAAAAAGCTGGAAGAA
    GTCAGTGGAATAAGCCAGCCTGTCATAGCTAGGATGGAGACAGGAAAGACTAGTCCTCAG
    TTGGATACAGTCTTAAAAGTCCTAGCCAGTTTAGGAAAGACACTAGCAGTCGTCCCACTT
    GAACAGGGAAAAAGTTGA
    60
    120
    180
    198

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_0576 [new locus tag: SPAP_RS02860 ]
  • symbol: SPAP_0576
  • description: Predicted transcriptional regulator
  • length: 65
  • theoretical pI: 6.78812
  • theoretical MW: 7012.1
  • GRAVY: -0.150769

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 49.5)
    and 3 more
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 17.5)
    Genetic information processing Mobile and extrachromosomal element functions Other probable addiction module antidote protein (TIGR02684; HMM-score: 14.9)
    RNA polymerase sigma-B factor (TIGR02941; HMM-score: 12.1)
  • TheSEED  :
    • transcription regulator, probable
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 49.5)
    and 8 more
    HTH_37; Helix-turn-helix domain (PF13744; HMM-score: 26.4)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 23.8)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 22.4)
    HTH_25; Helix-turn-helix domain (PF13413; HMM-score: 17.4)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 15)
    no clan defined AF2212-like; AF2212-like (PF01954; HMM-score: 13.4)
    HTH (CL0123) MqsA_antitoxin; Antitoxin component of bacterial toxin-antitoxin system, MqsA (PF15731; HMM-score: 13.2)
    Xre-like-HTH; Antitoxin Xre-like helix-turn-helix domain (PF20432; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9671
    • Cytoplasmic Membrane Score: 0.0035
    • Cell wall & surface Score: 0.0022
    • Extracellular Score: 0.0271
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010001
    • TAT(Tat/SPI): 0.002575
    • LIPO(Sec/SPII): 0.001085
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM84169 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSELIEARYEQGISQKKLEEVSGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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