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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_1198 [new locus tag: SPAP_RS05930 ]
  • pan locus tag?: PNEUPAN002024000
  • symbol: SPAP_1198
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1198 [new locus tag: SPAP_RS05930 ]
  • symbol: SPAP_1198
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1133774..1134403
  • length: 630
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP002121 (1133774..1134403) NCBI
  • BioCyc: see SPAP_RS05930
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    TTGAACAAGGCAAATCAACTCTTGGAACAAATCCATGAAGAAGGAATCAGACAATCCTTG
    GCAGAAGAAGTAGAAAATCTAAAAGCTGCCACAAACAAGGCTGATGCAGACTTGGATGAA
    GTAAACAGTCAGGTAAAAGATGTTTTGACTCGTATCGCTAGCGCCCTTCAACAAGAAAAG
    GAAAATGCTGAGCAAGATTCTCAGACACTTGTACTCTATCAAAAACTCTACGATATTCTC
    ATGTCGCTTCACTCTTATTTAGAAAGTAATAATGGATCTGATGCGGACTTTGATAAGGTG
    GATGCATTATTAGATCAACTTTCTGCTAATAGTAAAGACAAAACAGCTTTACTTGAATCG
    ACAAAAGCTATTCTAGTTTTGAATCATCAAATCCAGTCAAAAGTTAGCGCAAGTGAAGAA
    ACAAGTCCAGCAAGAAATGCTGAAGCAAATAGTGATAACACCAGTGCTGAGAACCAACCA
    AACGCAACTGCAGAATCTAACATTGAAACTGCTAGCGACGAAAACAAACCAAGCAATACA
    AGAGATTCTAAACCTGCTGAATCAACTTCAGAAAATGAAACAACAGAATCTTCTACAACT
    ACTGGAAATCAAGAAAAACCAGTAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    630

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPAP_1198 [new locus tag: SPAP_RS05930 ]
  • symbol: SPAP_1198
  • description: hypothetical protein
  • length: 209
  • theoretical pI: 4.07965
  • theoretical MW: 22811.4
  • GRAVY: -0.919617

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other hemophore (TIGR04530; HMM-score: 9.3)
  • TheSEED  :
    • FIG01113985: hypothetical protein
  • PFAM:
    tRNA_bind_arm (CL0298) Seryl_tRNA_N; Seryl-tRNA synthetase N-terminal domain (PF02403; HMM-score: 15.7)
    T3SS (CL0646) UPF0058; Uncharacterised protein family UPF0058 (PF01893; HMM-score: 13.7)
    Globin (CL0090) RsbRD_N; RsbT co-antagonist protein rsbRD N-terminal domain (PF14361; HMM-score: 13.1)
    no clan defined DUF6664; Family of unknown function (DUF6664) (PF20369; HMM-score: 12.6)
    and 4 more
    4H_Cytokine (CL0053) IFN-gamma; Interferon gamma (PF00714; HMM-score: 11.3)
    FUSC (CL0307) FUSC; Fusaric acid resistance protein family (PF04632; HMM-score: 10.5)
    no clan defined MHB; Haemophore, haem-binding (PF16525; HMM-score: 9.7)
    Prominin; Prominin (PF05478; HMM-score: 5.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.1417
    • Cytoplasmic Membrane Score: 0.1908
    • Cell wall & surface Score: 0.0902
    • Extracellular Score: 0.5774
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011839
    • TAT(Tat/SPI): 0.002811
    • LIPO(Sec/SPII): 0.002052
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM84786 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQVKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDALLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]