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NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_1291 [new locus tag: SPAP_RS06385 ]
  • pan locus tag?: PNEUPAN002552000
  • symbol: SPAP_1291
  • pan gene symbol?: dprA
  • synonym:
  • product: Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1291 [new locus tag: SPAP_RS06385 ]
  • symbol: SPAP_1291
  • product: Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
  • replicon: chromosome
  • strand: -
  • coordinates: 1227804..1228652
  • length: 849
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAG
    ATTTTGAAAGTGCTAGAATACGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATT
    GCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGGAACGTTATTTTCAGATAGAC
    GATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
    TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAAT
    CTTGACCTCCTGAAATTCCCGAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAG
    GGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAAATGAACTGGTTATTGTCAGT
    GGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
    ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTG
    CAAGACTACATCGGCAATGACCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCT
    CTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTGGACTTTGTCGTGGTGTGATT
    GTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
    GGACGCGATGTCTTTGCTATTCCTGCTAGCATTTTAGATGGACTATCAGACGGTTGCCAT
    CATTTGATTCAAGAAGGAGCAAAATTGCTCACCAGTGGGCAAGATGTTCTTGCGGAATTT
    GAATTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    849

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_1291 [new locus tag: SPAP_RS06385 ]
  • symbol: SPAP_1291
  • description: Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
  • length: 282
  • theoretical pI: 5.40641
  • theoretical MW: 31090.6
  • GRAVY: -0.043617

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes DNA transformation DNA protecting protein DprA (TIGR00732; HMM-score: 235.3)
  • TheSEED  :
    • Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake
    RNA Metabolism RNA processing and modification YrdC-YciO-Sua5 and associated protein families  Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake
  • ⊞PFAM:
    SLOG (CL0349) DNA_processg_A; DNA recombination-mediator protein A (PF02481; HMM-score: 248.3)
    and 4 more
    SAM (CL0003) SAM_DrpA; DNA processing protein A sterile alpha motif domain (PF18255; HMM-score: 99.5)
    SLOG (CL0349) YAcAr; YspA, cpYpsA-related SLOG family (PF10686; HMM-score: 15.6)
    LDcluster4; SLOG cluster4 family (PF18306; HMM-score: 14)
    HTH (CL0123) DBD_HTH; Putative DNA-binding domain (PF18430; HMM-score: 11.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003124
    • TAT(Tat/SPI): 0.000238
    • LIPO(Sec/SPII): 0.000732
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM84878 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGKTIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGRDVFAIPASILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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