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serotype 4
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serotype 6B
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serotype 6A
70585
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serotype 11A
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serotype 14
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Hu15
serotype 19A
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serotype 19A
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serotype 14
JJA
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MDRSPN001
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NCTC7466
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NU83127
serotype 4
OXC141
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R6
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SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_1706 [new locus tag: SPAP_RS08440 ]
  • pan locus tag?: PNEUPAN003101000
  • symbol: SPAP_1706
  • pan gene symbol?: acpS
  • synonym:
  • product: Phosphopantetheinyl transferase (holo-ACP synthase)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1706 [new locus tag: SPAP_RS08440 ]
  • symbol: SPAP_1706
  • product: Phosphopantetheinyl transferase (holo-ACP synthase)
  • replicon: chromosome
  • strand: -
  • coordinates: 1612220..1612588
  • length: 369
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAAATGATAGTTGGACACGGAATTGACATCGAAGAATTGGCTTCGATAGAAAGCGCA
    GTTACACGACATGAAGGATTTGCTAAGCGTGTACTGACTGCTCAGGAAATGGAGCGCTTC
    ACCAGTCTCAAAGGACGCAGGCAAATAGAATATTTAGCTGGTCGCTGGTCGGCTAAGGAG
    GCCTTTTCCAAGGCTATGGGAACGGGCATTAGCAAGCTCGGTTTTCAGGATTTGGAAGTA
    TTGAACAATGAACGTGGGGCGCCTTATTTTAGTCAGGCACCATTTTCAGGAAAGATTTGG
    CTGTCTATCAGCCACACCGATCAGTTTGTGACAGCCAGTGTCATTTTGGAGGAAAATCAT
    GAAAGCTAG
    60
    120
    180
    240
    300
    360
    369

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_1706 [new locus tag: SPAP_RS08440 ]
  • symbol: SPAP_1706
  • description: Phosphopantetheinyl transferase (holo-ACP synthase)
  • length: 122
  • theoretical pI: 6.52097
  • theoretical MW: 13647.4
  • GRAVY: -0.279508

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein modification and repair phosphopantetheine--protein transferase domain (TIGR00556; HMM-score: 96.1)
    Metabolism Fatty acid and phospholipid metabolism Biosynthesis holo-[acyl-carrier-protein] synthase (TIGR00516; EC 2.7.8.7; HMM-score: 87)
  • TheSEED  :
    • Holo-[acyl-carrier protein] synthase (EC 2.7.8.7)
    Fatty Acids, Lipids, and Isoprenoids Fatty acids Fatty Acid Biosynthesis FASII  Holo-[acyl-carrier protein] synthase (EC 2.7.8.7)
  • ⊞PFAM:
    4PPT (CL0670) ACPS; 4'-phosphopantetheinyl transferase superfamily (PF01648; HMM-score: 75.1)
    and 1 more
    4PPT_N; 4'-phosphopantetheinyl transferase N-terminal domain (PF17837; HMM-score: 37.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007639
    • TAT(Tat/SPI): 0.003355
    • LIPO(Sec/SPII): 0.000779
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85290 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSISHTDQFVTASVILEENHES

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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