PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 17-JAN-2018

⊟Summary

• organism: Streptococcus pneumoniae AP200
• locus tag: SPAP_1920 [new locus tag: SPAP_RS09515 ]
• pan locus tag^?: PNEUPAN003460000
• symbol: SPAP_1920
• pan gene symbol^?: recX
• synonym:
• product: Uncharacterized protein conserved in bacteria

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPAP_1920 [new locus tag: SPAP_RS09515 ]
• symbol: SPAP_1920
• product: Uncharacterized protein conserved in bacteria
• replicon: chromosome
• strand: +
• coordinates: 1799353..1800087
• length: 735
• essential: unknown

⊟Accession numbers

• Location: CP002121 (1799353..1800087) NCBI
• BioCyc: see SPAP_RS09515
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1705 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  
  ATGGAGCTTGATAATGGCGACAAATGCTATATCACCGAAGACACAATTGTTCGTTTTATG
  TTATCGAGAGATAAGGTGATAAGCGAAGAGGAATTGAAAGAGATTCAAGACTTTGCTCAA
  TTTTCTTATGGTAAGAATCTGGCCCTCTACCACTTATCCTTTAAAGCACGTACTGAAAAA
  GAGGTCAGAGAATATCTGAAAAAATATGATATTAATGAAAACATCGTTTCTCAAGTCATT
  GCTAATCTTAAAGAAGAGAAGTGGATTAATGATAGCCAGTACGCTTATGCTATCATCAAT
  GCCAATCAACTTTCAGGAGACAAGGGACCTTATGTACTGACTCAGAAATTAGCACAAAAA
  GGAATTTCAAAATCTACTATAGAAGAAATCTTGAATGATTTTGATTTTTCGGAAGTTGCT
  CAACGTGTAGCCAATAAACTATTGAAAAAATATGAGGGAAAACTTCCAGCTCGTGCCCTG
  CAAGATAAGATTATCCAGAACTTGACTAACAAGGGCTTCTCTTATTTTGATGCTAAAATT
  GCCTTTGACGAATTGGATAGTCAAGTTGATGAAGAAACGACTCAGGAACTCATCTTCAAG
  GAACTTGATAAGCAATATACTAAGTATGCCCGAAAGTATGAAGGATACGAACTGAAGCAG
  CGTTTAACTCAAGTTTTAGCACGAAAGGGCTACGATTTTTCGGATATAGCAAGCGCTCTT
  AGAGAATATCTTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  735
  

⊟Protein

⊟General

• locus tag: SPAP_1920 [new locus tag: SPAP_RS09515 ]
• symbol: SPAP_1920
• description: Uncharacterized protein conserved in bacteria
• length: 244
• theoretical pI: 5.00175
• theoretical MW: 28495
• GRAVY: -0.631967

⊟Function

• TIGRFAM:
  Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis phosphoribosylamine--glycine ligase (TIGR00877; EC 6.3.4.13; HMM-score: 12.5)
  Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 11.9)
  and 1 more
  Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein uS17 (TIGR03630; HMM-score: 9.6)
• TheSEED  :
  • Regulatory protein RecX
• PFAM:
  no clan defined RecX; RecX family (PF02631; HMM-score: 114.9)
  and 10 more
  CLAMP; Flagellar C1a complex subunit C1a-32 (PF14769; HMM-score: 13.8)
  HTH (CL0123) DUF6471; Domain of unknown function (DUF6471) (PF20075; HMM-score: 13.7)
  ATP-grasp (CL0179) GARS_A; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (PF01071; HMM-score: 13.6)
  GAD (CL0250) GAD-like; GAD-like domain (PF08887; HMM-score: 13.4)
  TPR (CL0020) PPP5; PPP5 TPR repeat region (PF08321; HMM-score: 12.5)
  no clan defined SRP54_N; SRP54-type protein, helical bundle domain (PF02881; HMM-score: 12.3)
  Tli4_N; Tle cognate immunity protein 4 N-terminal domain (PF18443; HMM-score: 11.4)
  HTH (CL0123) Mnd1; Mnd1 HTH domain (PF03962; HMM-score: 11.2)
  no clan defined DUSP; DUSP domain (PF06337; HMM-score: 9.1)
  SufE_NifU (CL0233) Lip_prot_lig_C; Bacterial lipoate protein ligase C-terminus (PF10437; HMM-score: 9.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9573
  • Cytoplasmic Membrane Score: 0.0023
  • Cell wall & surface Score: 0.0002
  • Extracellular Score: 0.0402
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.001911
  • TAT(Tat/SPI): 0.000198
  • LIPO(Sec/SPII): 0.000507
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: ADM85483 NCBI
• UniProt:

⊟Protein sequence

• MELDNGDKCYITEDTIVRFMLSRDKVISEEELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKWINDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANKLLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDKQYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1705 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications