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serotype 4
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serotype 19A
Hu17
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serotype 14
JJA
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SPN994038
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ST556
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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_2253 [new locus tag: SPAP_RS11140 ]
  • pan locus tag?: PNEUPAN003905000
  • symbol: SPAP_2253
  • pan gene symbol?: cysK
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_2253 [new locus tag: SPAP_RS11140 ]
  • symbol: SPAP_2253
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2099115..2100035
  • length: 921
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTCTATTTATAACAACATTACTGAATTAATCGGTCAAACACCGATTGTTAAACTTAAC
    AACATCGTGCCAGAAGGTGCTGCAGACGTCTATATAAAGCTTGAAGCATTTAATCCTGGT
    TCATCTGTAAAAGACCGTATTGCCCTTAGCATGATTGAAAAAGCTGAACAAGATGGTATT
    CTGAAACCTGGTTCTACTATTGTTGAAGCAACAAGTGGAAACACTGGTATTGGACTTTCA
    TGGGTAGGTGCTGCTAAAGGGTATAAAGTCGTCATCGTTATGCCTGAAACTATGAGTGTA
    GAACGACGTAAAATTATCCAAGCTTATGGTGCTGAACTCGTCCTAACTCCTGGTAGCGAG
    GGAATGAAAGGTGCTATTGCTAAGGCTCAAGAAATCGCTGCTGAACGTGATGGTTTCCTT
    CCTCTTCAATTTGACAATCCAGCTAATCCAGAAGTACACGAAAGAACAACAGGAGCTGAG
    ATACTAGCTGCTTTCGGTAAAGATGGATTAGATGCCTTTGTTGCTGGAGTAGGTACCGGT
    GGAACGATTTCTGGTGTTTCTCATGCACTCAAATCAGAAAATTCTAACATTCAAGTTTTT
    GCAGTAGAAGCAGATGAATCTGCTATTCTATCTGGTGAAAAACCTGGTCCTCACAAAATT
    CAAGGTATCTCAGCTGGATTTATTCCTGATACACTTGATACTAAAGCCTATGATGGTATC
    GTTCGTGTAACATCAGATGACGCTCTTGCACTCGGACGTGAAATTGGTGGAAAAGAAGGC
    TTCCTTGTAGGGATTTCCTCAGCTGCAGCTATCTACGGAGCCATCGAGGTTGCCAAAAAA
    TTAGGTACAGGTAAAAAAGTCCTTGCCCTAGCACCAGATAACGGTGAACGTTATCTCTCT
    ACAGCACTTTATGAATTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    921

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_2253 [new locus tag: SPAP_RS11140 ]
  • symbol: SPAP_2253
  • description: hypothetical protein
  • length: 306
  • theoretical pI: 4.68169
  • theoretical MW: 31857
  • GRAVY: 0.0470588

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Amino acid biosynthesis Serine family cysteine synthase A (TIGR01139; EC 2.5.1.47; HMM-score: 431)
    Metabolism Amino acid biosynthesis Serine family cysteine synthase (TIGR01136; EC 2.5.1.47; HMM-score: 408.5)
    and 13 more
    Metabolism Amino acid biosynthesis Serine family cysteine synthase B (TIGR01138; EC 2.5.1.47; HMM-score: 280.3)
    Metabolism Amino acid biosynthesis Serine family cystathionine beta-synthase (TIGR01137; EC 4.2.1.22; HMM-score: 278.6)
    Cellular processes Cellular processes Biosynthesis of natural products 2,3-diaminopropionate biosynthesis protein SbnA (TIGR03945; HMM-score: 230.2)
    Metabolism Amino acid biosynthesis Pyruvate family threonine ammonia-lyase (TIGR01127; EC 4.3.1.19; HMM-score: 78)
    Metabolism Amino acid biosynthesis Pyruvate family threonine ammonia-lyase, biosynthetic (TIGR01124; EC 4.3.1.19; HMM-score: 63.7)
    Metabolism Amino acid biosynthesis Pyruvate family threonine dehydratase (TIGR02079; EC 4.3.1.19; HMM-score: 54.1)
    Metabolism Amino acid biosynthesis Aspartate family threonine synthase (TIGR00260; EC 4.2.3.1; HMM-score: 41.7)
    ectoine utilization protein EutB (TIGR02991; HMM-score: 40.6)
    diaminopropionate ammonia-lyase (TIGR03528; EC 4.3.1.15; HMM-score: 27.1)
    Metabolism Energy metabolism Other diaminopropionate ammonia-lyase family (TIGR01747; EC 4.3.1.15; HMM-score: 26.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other cysteate synthase (TIGR03844; EC 2.5.1.76; HMM-score: 17.1)
    Metabolism Energy metabolism Methanogenesis cysteate synthase (TIGR03844; EC 2.5.1.76; HMM-score: 17.1)
    pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family (TIGR01275; HMM-score: 13.5)
  • ⊞TheSEED  :
    • Cysteine synthase (EC 2.5.1.47)
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Cysteine Biosynthesis  Cysteine synthase (EC 2.5.1.47)
    and 1 more
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  Cysteine synthase (EC 2.5.1.47)
  • ⊞PFAM:
    NADP_Rossmann (CL0063) PALP; Pyridoxal-phosphate dependent enzyme (PF00291; HMM-score: 222.9)
    and 1 more
    PRMT5; PRMT5 arginine-N-methyltransferase (PF05185; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008994
    • TAT(Tat/SPI): 0.000227
    • LIPO(Sec/SPII): 0.000351
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85784 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVKDRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVERRKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAEILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPHKIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIEVAKKLGTGKKVLALAPDNGERYLSTALYEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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