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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-FEB-2023

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS04475 [old locus tag: SPAP_0901 ]
  • pan locus tag?: PNEUPAN000315000
  • symbol: mobC
  • pan gene symbol?: mobC
  • synonym:
  • product: plasmid mobilization protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS04475 [old locus tag: SPAP_0901 ]
  • symbol: mobC
  • product: plasmid mobilization protein
  • replicon: chromosome
  • strand: -
  • coordinates: 861465..861821
  • length: 357
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_014494 (861465..861821) NCBI
  • BioCyc: SPAP_RS04475 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGGCAAATAGATTTAGAAATGAAAGAATAGAAATAAAATTAACTAAGGAAGAAAAGGAA
    GTTTTTGAAAAGAAAATGAAACTTGCAAATTGCAAAACCATGTCCCACTTTCTTAGGAAA
    TGTGTATTAGAAAAAGAAATTTATGTTGTAGATTTAGAACCATTTAGAAACTTACAATGG
    CTACTTTCAAATGCAACAAATAATATAAACCAGATCGCCAAGGCTACTAATACAACTGGT
    GTTATTTACAAAAATGAAATTGAAGCAATGAATAAAGAAATAGAAAAATTATCAAGAGAA
    ATATGGCAGATTCATTCCCTACTTCTTAATAAATCAAAAGAAAGTTCTGGTGATTAA
    60
    120
    180
    240
    300
    357

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPAP_RS04475 [old locus tag: SPAP_0901 ]
  • symbol: MobC
  • description: plasmid mobilization protein
  • length: 118
  • theoretical pI: 9.55679
  • theoretical MW: 13930.1
  • GRAVY: -0.629661

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SPAP_0901
  • PFAM:
    Met_repress (CL0057) MobC_2; MobC-like protein (PF19514; HMM-score: 28)
    MobC; Bacterial mobilisation protein (MobC) (PF05713; HMM-score: 27.6)
    and 8 more
    DUF6290; Family of unknown function (DUF6290) (PF19807; HMM-score: 18.7)
    no clan defined Phasin; Poly(hydroxyalcanoate) granule associated protein (phasin) (PF05597; HMM-score: 15.4)
    Snx8_BAR_dom; Sorting nexin 8/Mvp1 BAR domain (PF19566; HMM-score: 15)
    DUF359; Protein of unknown function (DUF359) (PF04019; HMM-score: 14.4)
    6PGD_C (CL0106) DUF2520; Domain of unknown function (DUF2520) (PF10728; HMM-score: 13.5)
    Met_repress (CL0057) DUF1778; Protein of unknown function (DUF1778) (PF08681; HMM-score: 13.2)
    no clan defined TCP; TCP family transcription factor (PF03634; HMM-score: 11.4)
    Mrpl_C; 54S ribosomal protein L8 C-terminal domain (PF18502; HMM-score: 9.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8339
    • Cytoplasmic Membrane Score: 0.0367
    • Cell wall & surface Score: 0.027
    • Extracellular Score: 0.1024
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006307
    • TAT(Tat/SPI): 0.000441
    • LIPO(Sec/SPII): 0.00057
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000013364 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MANRFRNERIEIKLTKEEKEVFEKKMKLANCKTMSHFLRKCVLEKEIYVVDLEPFRNLQWLLSNATNNINQIAKATNTTGVIYKNEIEAMNKEIEKLSREIWQIHSLLLNKSKESSGD

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]