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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 22-FEB-2023
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae AP200
- locus tag: SPAP_RS05840 [old locus tag: SPAP_1180 ]
- pan locus tag?: PNEUPAN002041000
- symbol: SPAP_RS05840
- pan gene symbol?: tdk
- synonym:
- product: thymidine kinase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPAP_RS05840 [old locus tag: SPAP_1180 ]
- symbol: SPAP_RS05840
- product: thymidine kinase
- replicon: chromosome
- strand: -
- coordinates: 1117831..1118430
- length: 600
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_014494 (1117831..1118430) NCBI
- BioCyc: SPAP_RS05840 BioCyc
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0904 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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541ATGGCACAGTTGTATTATCGTTATGGGACCATGAACTCTGGTAAAACGATTGAGATTCTC
AAAGTGGCCTATAACTACGAGGAGCAAGGAAAAGGTGTTGTCATTATGACTTCGGCTCTG
GATACGCGTGACGGTGTTGGCTATGTGTCGAGTCGAATTGGCATGAAACGCCCTGCCCTT
ACGATTGAGGAAACAACGGATATCTTTGGCTATATCCGAGACCTACCAGAAAAACCTTAC
TGTGTTTTGGTCGATGAAGCCCAGTTTCTCAAACGCCACCATGTTTACGACCTAGCTCGT
GTTGTGGACGAGTTAGACATACCCGTCATGGCTTTTGGCTTGAAAAATGACTTTCGCAAT
GAATTGTTCGAAGGTTCCAAATATCTCTTGCTTTTAGCAGACAAGATTGACGAAATCAAG
ACCATCTGTCAGTATTGCAAGAAAAAGGCGACCATGGTGTTGCGAACACAGGATGGACTG
CCCGTTTACGATGGAGAACAGATCCAGATTGGTGGTAATGAAACCTATATTTCGGTTTGC
CGTAAACATTATTTTGCGCCAATGATAACCTCTAACAAGGAGCAAAACTATGACAATTGA60
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600
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPAP_RS05840 [old locus tag: SPAP_1180 ]
- symbol: SPAP_RS05840
- description: thymidine kinase
- length: 199
- theoretical pI: 5.77264
- theoretical MW: 22856.1
- GRAVY: -0.335678
⊟Function[edit | edit source]
- reaction: EC 2.7.1.21? ExPASyThymidine kinase ATP + thymidine = ADP + thymidine 5'-phosphate
- TIGRFAM:
- TheSEED: see SPAP_1180
- PFAM: P-loop_NTPase (CL0023) TK; Thymidine kinase (PF00265; HMM-score: 170.2)and 2 moreAAA_30; AAA domain (PF13604; HMM-score: 14.6)KdpD; Osmosensitive K+ channel His kinase sensor domain (PF02702; HMM-score: 12.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9925
- Cytoplasmic Membrane Score: 0.0008
- Cell wall & surface Score: 0
- Extracellular Score: 0.0068
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004203
- TAT(Tat/SPI): 0.000249
- LIPO(Sec/SPII): 0.000501
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000068153 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPALTIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGLPVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0904 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]