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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 07-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS06650 [old locus tag: SPAP_1343 ]
  • pan locus tag?: PNEUPAN000232000
  • symbol: SPAP_RS06650
  • pan gene symbol?: ntpD
  • synonym:
  • product: V-type ATP synthase subunit D

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS06650 [old locus tag: SPAP_1343 ]
  • symbol: SPAP_RS06650
  • product: V-type ATP synthase subunit D
  • replicon: chromosome
  • strand: -
  • coordinates: 1268997..1269608
  • length: 612
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014494 (1268997..1269608) NCBI
  • BioCyc: SPAP_RS06650 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGTGCGTTTGAATGTAAAACCAACTCGTATGGAATTGAATAACTTAAAGGAACGTTTG
    AAAACAGCTGAACGTGGACATAAGTTATTAAAGGATAAAAGAGATGAATTGATGAGGCGA
    TTTATTTCTTTGATTCGTGAGAATAATCAACTTCGGAAAGAAGTAGAAAGTTATCTAATT
    GATAATCTAAAAGCCTTTGCAGTTGCTAAATCATTAAAGAACTCTCTAATGGTGGAGGAA
    TTATTTTCAATTCCATCGAAAGAAATTGAATTATTTGTTGAGAAAGAAAATATCATGAGT
    GTAACAGTTCCTAGAATGCATATGAATATTACTTCTCAAAATGAGAACAGTGAATACAGC
    TATTTATCTTCTAATAGTGAAATGGATGATGTATTTGCTACAATGAATAGTTTAATTGAT
    AAATTACTAAGACTGGCAGAAGTTGAAAAAACGTGTCAGTTAATGGCTGATGAAATAGAA
    AAAACACGTAGACGTGTAAATGGATTAGAATATTCGATTATTCCAAACTTGTCAGAAACT
    ATTCATTATATAGAATTGAAACTAGAGGAGGCAGAAAGAGCCAATTTAGTTCGGATTATG
    AAAGTGAAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    612

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_RS06650 [old locus tag: SPAP_1343 ]
  • symbol: SPAP_RS06650
  • description: V-type ATP synthase subunit D
  • length: 203
  • theoretical pI: 8.42418
  • theoretical MW: 23865.6
  • GRAVY: -0.472414

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 7.1.2.2?  ExPASy
    non-specified enzyme name
  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds V-type ATPase, D subunit (TIGR00309; EC 3.6.3.14; HMM-score: 153.5)
    and 1 more
    SH3 domain protein (TIGR04211; HMM-score: 8.7)
  • TheSEED: see SPAP_1343
  • ⊞PFAM:
    no clan defined ATP-synt_D; ATP synthase subunit D (PF01813; HMM-score: 174.9)
    and 6 more
    Cep57_CLD_2; Centrosome localisation domain of PPC89 (PF14197; HMM-score: 15.1)
    TSC22; TSC-22/dip/bun family (PF01166; HMM-score: 13.8)
    bZIP (CL0018) bZIP_2; Basic region leucine zipper (PF07716; HMM-score: 13.7)
    no clan defined HALZ; Homeobox associated leucine zipper (PF02183; HMM-score: 13.4)
    Occludin_ELL; Occludin homology domain (PF07303; HMM-score: 12.5)
    GT-B (CL0113) DUF3492; Domain of unknown function (DUF3492) (PF11997; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003819
    • TAT(Tat/SPI): 0.000412
    • LIPO(Sec/SPII): 0.00103
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000251931 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLIDNLKAFAVAKSLKNSLMVEELFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIEKTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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